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11 Cards in this Set

  • Front
  • Back
what are the 4 main symptoms of Meningitis?

-All 4 are not usually found together, but if none of these are found, then usually not dealing with meningitis
HA
nuchal rigidity
fever
change in mental status
What are the 3 most common bacterial causes of Meningitis and what is their gram stain morphology?(starting with most common)
Streptococcus Pneumoniae, (+) cocci
Neisseria meningitidis, (-) diplococci
Hemophilis influenzae type B, (-) rod
Where did the infection come from?

Haemophilus influenzae
-transfer via ...

Neisseria meningitidis
-normal flora of ...
-recent ... infection is a risk facter

Streptoccus pneumoniae
-normal flora of ...
-secondary to sinusitis, otitis media, bacteremia
respiratory droplets
nasopharynx
viral
nasopharynx
Treatment for Bacterial Meningitis (if we don’t know what it is.)
-give ... first if we suspect Meningitis
-give ... because resistance is increasing.

Infants (0-3 months)
-... + ... + ... (>1 mo.)

3 months to 50 years
- ... + ...

>50 years
-... + ... + ...

-depending on what stage they are in, steroids might be given to reduce inflammation.
-Tylenol to get fever down, cooling blanket
antibiotics
vancomycin

ampicillin
3rd generation cephalosporin
vancomycin

3rd gen. cephalosporin
vancomycin

Ampicillin
3rd. gen. cephalosporin
vancomycin
...:

Common mold
Inhalation of airborne spores
Taken up by alveolar macrophages
Causes allergies in healthy people
Allergic bronchopulmonary ...
-asthmatics
Sinusitis, pneumonia
... in immunocompromised patients
Predilection for invading blood vessel walls
-Cause cerebral vascular thrombosis and hemorrhagic infarction
Aspergillus
aspergillosis
Meningitis
...:

-Encapsulated yeast, present in soil and bird droppings (pigeons)
-Inhaled
-... (polysaccharide) capsule inhibits phagocytosis by alveolar macrophages
-Capsule is highlighted by India ink preparation
-... – changes in structure and size of polysaccharide capsule to evade immune response
-Occasionally causes headaches, meningoencephalitis in healthy patients
-Opportunistic pathogen in pts with immunosuppression (HIV/AIDS, leukemia, lymphoma, SLE, Hodgkin’s dz, sarcoidosis, transplant recipient, corticosteroid use)
Cryptococcus neoformans
Mucoid
Phenotypic switching
...:

Immunocompetent – self limited flu like illness

Transplacental transmission
-stillbirth, abortion, blindness, mental retardation
-part of TORCH (...)

AIDS pts, particularly with low CD4 count
-... infection
*irregular ring ring-enhancing lesions on CT and MRI scans
-Septic shock
Toxoplasma gondii
toxoplasmosis, rubella, cytomegalovirus, herpes
CNS
The mucoid capsule of which organism is highlighted by an India ink preparation?

a. toxoplasmosis
b. echinococcus granulosis
c. taenia solium
d. cryptococcus
e. acanthamoeba
d. cryptococcus
...:

-60 percent are in pts younger than 20 YO
-Dura is fused to the periosteum on the inner surface of the skull
-Vessels in dura can be injured especially with skull fractures
-Trauma to the temporal bone -> leads to tearing of ... artery
-... are uncommon over the age of 50 --> dura is strongly adherent to skull
-Blood accumulates and separates dura from skull
-... has smooth inner contour
-Classically -> pts have a lucid interval and subsequent headache, vomiting, seizure, loss of consciousness
Epidural Hematoma
middle meningeal
Epidural hematomas
Hematoma
...:

-Dural bridging veins travel from the surface of the cerebral hemispheres through the subarachnoid space and subdural space and empty with dural vessels into the ... sinus
-These veins are susceptible to tearing within the ... space as a result of trauma
-In the elderly the brain shrinks in size and the bridging veins are stretched out increasing the risk for ... after head trauma
-... are also susceptible to subdural hematomas because their bridging veins have thin walls
-Most patients with ... develop symptoms within 48 hrs after the injury – headache, confusion
Subdural Hematoma
superior sagittal
subdural
subdural hematoma
Infants
subdural hematomas
...:

Most frequent cause of significant ... is rupture of a saccular (berry) aneurysm
-thin-walled outpouching of vessel

Other causes include extension of traumatic hematoma, rupture of a hypertensive intracerebral hemorrhage into the ventricles, vascular malformation, coagulopathy, tumors
Subarachnoid Hemorrhage (SAH)
SAH