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122 Cards in this Set

  • Front
  • Back

What makes up tissue

Group of specialized cells

Caudal

Towards the animals tail

Cranial

Towards the animals head

Rostral

Towards the animals nose

Dorsal

Towards the vertebral column

Ventral

Away from the vertebral column ; towards the abdomen

Plantar

Distal, caudal region of the pelvic limb

Plantar

Distal, caudal region of the pelvic limb

Palmer

Distal, caudal region of the thoracic limb

Proximal

Towards near to a point of origin or articulation

Distal

Away from a point of origin or articulation

Deep

Away from the surface of a region of the anatomical component towards its center

Superficial

At the surface or near the surface of a region of the anatomical component towards its center

Prone

Ventral down and dorsal is outermost

Supine

Dorsal is down and ventral is outermost

Planes

Imaginary lines that go through animals

Median plane

Divides the animal into equal mirror image parts

Sagittal plane

Parallel to the median plane

Dorsal plane

Plane that divides animal into dorsal and ventral halves

Transverse plane

Plane that is at a 90 degree angle to the median plane

Medial plane

Towards the median

Medial plane

Towards the median

Lateral plane

Away from the median

Anatomy

The science of form and structure

Physiology

The science of the integrated functions of the body and all of its parts including biochemical and biophysical processes

What is a cell

Basic unit of an animal

3 main parts of a cell

A. Cell membrane


•creates a barrier to control both entry and exit of particles and messages



B. Cytoplasm


•cellular fluid and the organelles



C. Nucleus


•contains the genetic material

4 types of tissue

A. Epithelium


•tissue that covers the surface of the body, lines a cavity, forms glands



B. Connective tissue


•tissue that connects other tissues, provides structural support and protection



C. Muscle tissue


•specialized tissue that facilitates movement



D. Nervous tissue


•consists of neurons, which conduct electrical impulses, and supportive neuroglia cells

4 types of epithelial tissue

A. Squamous- on surface suffering a lot of abrasions


1.simple squamous


2.stratified squamous



B. Cuboidal


•highly secretory, found where lots of secretion occurs i.e glands



C. Columnar- important for secretion and adsorption, found in digestive tract


1. Pseudo stratified columnar- appears to have more than one layer, found in respiratory tract



D. Transitional epithelial


•found in bladder, large amorphic cells

3 types connective tissue

A. Connective tissue proper


•classified as loose, includes fat and tissue, and dense tightly packed (tendons/ligaments)



B. Fluid connective tissue


•blood and lymph


*blood-RBC & WBC


*lymph-extra cellular fluid will have WBC



C. Supporting connective tissue


•includes cartilage and bone

3 types of muscle tissue

A. Skeletal (striated)


•movement is voluntary, facilitates skeletal movement, found in biceps



B. Smooth


•movement is involuntary also make up sphincters (anus)



C. Cardiac (striated)


•movement is involuntary branched and connected, only found in heart

Components of the cell membrane

A. Phospholipid bilayer


1. Protein moiety outside & inside the cell (hydrophilic)


2. Fatty acid tail between protein moiety (hydrophobic)


3. Creates a barrier to regulate cellular environment


4. Increase surface area



B. Large proteins


1. Transport substances across membrane


2. Binding/docking site for extra cellular messengers (hormones)


3. Assist in cell-to-cell contact


•cell adhesion molecules adherence of membrane to membrane


4. Cell type recognition

Components of the cell membrane

A. Phospholipid bilayer


1. Protein moiety outside & inside the cell (hydrophilic)


2. Fatty acid tail between protein moiety (hydrophobic)


3. Creates a barrier to regulate cellular environment


4. Increase surface area


5. Facilitate movement



B. Large proteins


1. Transport substances across membrane


2. Binding/docking site for extra cellular messengers (hormones)


3. Assist in cell-to-cell contact


•cell adhesion molecules adherence of membrane to membrane


4. Cell type recognition

Microvilli

•Small finger like extensions used for better absorption


•is part of the phospholipid bilayer

Cilia

•Long finger like extensions used to move material past cell surface


•is not part of the phospholipid bilayer

2 types of protein channels

1. Leaky channel


•unregulated



2. Gated channel


•regulated

Carrier protein

Carries a substance across the membrane (glucose transporter)

Receptors

Large proteins that span across the cell membrane to transmit a signal

Lactase

Enzyme that cleaves lactose

Lactase

Enzyme that cleaves lactose

Lipase

Enzyme that cleaves lipids

2 types or categories of large membrane proteins

1. Integral


•proteins that are firmly inserted into the membrane. May also span across the membrane, called transmembrane proteins (channels that allow entry/exit of molecules)



2. Peripheral


•bound to the surface of the cell membrane

2 types or categories of large membrane proteins

1. Integral


•proteins that are firmly inserted into the membrane. May also span across the membrane, called transmembrane proteins (channels that allow entry/exit of molecules)



2. Peripheral


•bound to the surface of the cell membrane

Passive transport

Does not require energy

2 types or categories of large membrane proteins

1. Integral


•proteins that are firmly inserted into the membrane. May also span across the membrane, called transmembrane proteins (channels that allow entry/exit of molecules)



2. Peripheral


•bound to the surface of the cell membrane

Passive transport

Does not require energy

Active transport

Requires the use of energy to transport across the cell membrane



•ATP-primary


•Kinetic-secondary

Diffusion

Passive molecular movement of solutes the rate is determined by:


•concentration gradient


*greater conc->lower conc



•size of molecules


*smaller=faster



•charges of the molecules



•temperature


*hotter temp=faster movement


•lipid solubility


*greater lipid content= ^ diffusion

Facilitated diffusion

Carrier system where one molecule passively crosses the membrane when another membrane passively helps it across the membrane

Glucose transporter

Function is to transport glucose across the plasma membrane

Glut 1

•RBC


•strong concentration


•increases uptake

Glut 2

•liver


•Bidirectional


•in->glycolysis


•out->gluconeogenesis

Glut 3

•neurons


•concentration gradient =>increases uptake

Glut 4

•Hormone responsive


•found in muscle and fat


•only activated when insulin is present

Osmosis

Passive movement of water molecules toward a solution containing a higher solute concentration

Osmotic pressure

Driving force that moves water from the side that contains a lower solute concentration to a higher solute concentration

Hydrostatic pressure

Physical, volumetric pressure created from osmosis

Isotonic

Same solute concentration on either side of the membrane barrier

Hypotonic

Bathing solution has a lower solute concentration



RBC lyse

Hypertonic

Bathing solution has a higher solute concentration



RBC crenation

Primary transport

Movement across the cell membrane that consumes energy in the form of ATP

Secondary transport

Movement across the cell membrane that consumes energy in the form of stored ionic concentration gradient

Secondary transport

2 carrier protein systems:


A. Antiporter-go in different directions



B. Symporter-go in the same direction

Vesicle

Phospholipid membrane spherical organelle

Vesicle

Phospholipid membrane spherical organelle

What are the functions of vesicles

A. Containment


B. Transportation

Endocytosis

Extracellular materials that move into a cell in a vesicle formed from the plasma membrane

Endocytosis

Extracellular materials that move into a cell in a vesicle formed from the plasma membrane

Exocytosis

Expulsion of materials from a cell through a vesicle that fuses with cell membrane

Receptor mediated

Small molecule binding to the surface of plasma membrane stimulating vesicle formation

Receptor mediated

Small molecule binding to the surface of plasma membrane stimulating vesicle formation

Ligand

Molecule that binds to a receptor

Receptor mediated

Small molecule binding to the surface of plasma membrane stimulating vesicle formation

Ligand

Molecule that binds to a receptor

Phagocytosis

Cellular engulfing of a large substance upon receptor notification

Receptor mediated

Small molecule binding to the surface of plasma membrane stimulating vesicle formation

Ligand

Molecule that binds to a receptor

Phagocytosis

Cellular engulfing of a large substance upon receptor notification

Purpose of phagocytosis

•immune cells to clear foreign substance from the body



•immune cells to clear damaged tissue


*forms a phagosome


-marked for death

Lysosome

•Digestive vesicle- programmed to hold until it's ready to release


•contains digestive enzymes

Pinocytosis

•Engulfing small amounts of fluid


•no receptors involved

Transmembrane (electrical) potential

•Potential difference across a cell membrane


•cells are polarized in charge


•measured in volts

Potential difference

Separation of + and - charges across the membrane

Resting potential

Transmembrane potential in an undisturbed cell

Action potential

Rapid, short-lived reversal in intracellular electrical potential

Depolarization

Resting membrane potential changes from negative to positive

Nucleus

Contains genetic material; DNA

Nucleolus

Contain genetic material for ribosomes

Ribosome

Specialized large protein that contains RNA

Ribosome

Specialized large protein that contains RNA

Function of ribosome

Synthesize proteins

Ribosome

Specialized large protein that contains RNA

Function of ribosome

Synthesize proteins

mRNA

•Messenger RNA


*genetic code to make a protein

Endoplasmic reticulum

Phospholipid bilayer that is continuous with the nuclear membrane

Endoplasmic reticulum

Phospholipid bilayer that is continuous with the nuclear membrane

Smooth ER

1. Stores Ca


2. Stores glycogen


3. Site of cholesterol synthesis


4. Site of lipid synthesis

Endoplasmic reticulum

Phospholipid bilayer that is continuous with the nuclear membrane

Smooth ER

1. Stores Ca


2. Stores glycogen


3. Site of cholesterol synthesis


4. Site of lipid synthesis

Rough ER

1. Site of protein synthesis


2. Ribosomes attach to the surface

Endoplasmic reticulum

Phospholipid bilayer that is continuous with the nuclear membrane

Smooth ER

1. Stores Ca


2. Stores glycogen


3. Site of cholesterol synthesis


4. Site of lipid synthesis

Rough ER

1. Site of protein synthesis


2. Ribosomes attach to the surface

Golgi apparatus

1. Packages synthesized molecules


2. Responsible for post synthesis modifications

Mitochondria

1. Energy making organelle


2. Responsible for producing ATP

Mitochondria

1. Energy making organelle


2. Responsible for producing ATP

Brown fat

•Found in neonates or hibernating animals


•loaded with mitochondria

Mitochondria

1. Energy making organelle


2. Responsible for producing ATP


3. Producing heat

Brown fat

•Found in neonates or hibernating animals


•loaded with mitochondria

White fat

Throughout a lifetime

Osteogenic cell

Produces progenitor cells

Functions of osteogenic

1. Make more Progenitor Cells


2. Transform into an osteoblasts

Osteoblast

Secrete bone matrix

What does the Bone matrix consist of?

1. Organic


•collagen (filler to trap minerals)


•glycosaminoglycan (scaffold)


1/3 of the bone matrix



2. Inorganic


•mineral-(Fe, Na, Mg)


*calcium phosphate- 80%


*calcium carbonate- 20%

Osteocyte

Mature bone cell



Origin=hematopoietic cell line



Lysosomal enzymes-break down organic part



Phosphoric acid-break down mineral

Osteon

Circular region of living bone tissue

Central canal

Houses a blood vessel


A. Bringing nutrients to tissue


B. Taking waste away from tissue

Lacunae

Location of the cell body of an osteocyte

Canaliculi

Walled in cytoplasmic extensions of osteocytes


•connect to the central for the transfer of nutrients & waste

What makes up the inner and outer parts of the bone cell and what are they made up of?

Periosteum & Endosteum which are made up of osteogenic cells

Osteology

Study of bones

Functions of bones

1. Protection


•skull & vertebral column


•rib cage


•pelvis


2. Shape/Form


•external structure and appearance


3. Leverage


•assist in movement by providing an attachment site for muscles


4. Blood formation


•platelets, RBC, and WBC in red marrow


5. Lipid storage


•in yellow marrow


6. Mineral storage


•65% inorganic substances