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63 Cards in this Set

  • Front
  • Back

Viability

The probability that a genotype survives from fertilisation to reproductive age

Absolute fitness

Its value is independent of the fitness of other genotypes

Relative fitness

Fitness value id expressed relative to another genotype

Relative fitness representative

w, when w=1 then the genotype has the maximum survival ability

Relative fitness wrt A1A1 homozygote

w11 = W11/W11


w12 = W12/W11


w22 = W22/W11

Selection coefficient (s)

Expressed as reduction in fitness relative to the best genotype, s = 1- w

Higher the selection coefficient

Stronger the selection pressure against that particular genotype

Higher the selection coefficient

Stronger the selection pressure against that particular genotype

Negative selection

Alleles that lower the fitness

Higher the selection coefficient

Stronger the selection pressure against that particular genotype

Negative selection

Alleles that lower the fitness

Positive selection

Alleles that increase fitness

Higher the selection coefficient

Stronger the selection pressure against that particular genotype

Negative selection

Alleles that lower the fitness

Positive selection

Alleles that increase fitness

Balancing selection

When selection favors the heterozygotes (heterozygote advantage) at the expense of homozygotes

Higher the selection coefficient

Stronger the selection pressure against that particular genotype

Negative selection

Alleles that lower the fitness

Positive selection

Alleles that increase fitness

Balancing selection

When selection favors the heterozygotes (heterozygote advantage) at the expense of homozygotes

Frequency dependent selection

Fitness of a genotype depends on its frequency within the population

Higher the selection coefficient

Stronger the selection pressure against that particular genotype

Negative selection

Alleles that lower the fitness

Positive selection

Alleles that increase fitness

Balancing selection

When selection favors the heterozygotes (heterozygote advantage) at the expense of homozygotes

Frequency dependent selection

Fitness of a genotype depends on its frequency within the population

Density dependent selection

Fitnesses are functions of the population size

Higher the selection coefficient

Stronger the selection pressure against that particular genotype

Negative selection

Alleles that lower the fitness

Positive selection

Alleles that increase fitness

Balancing selection

When selection favors the heterozygotes (heterozygote advantage) at the expense of homozygotes

Frequency dependent selection

Fitness of a genotype depends on its frequency within the population

Density dependent selection

Fitnesses are functions of the population size

Negative frequency dependent selection

Relative fitness of a genotype is high when it is rare and low when it is common

Positive frequency dependent selection

Fitness of an allele or a genotype increases as its frequency increases

Genetic Drift

The random change in allele frequencies simply as a result of chance due to sampling error from one generation to next in a finite population

Genetic Drift

The random change in allele frequencies simply as a result of chance due to sampling error from one generation to next in a finite population

Effect of genetic drift

Minimal in large populations whereas maximum in small ones

Genetic Drift

The random change in allele frequencies simply as a result of chance due to sampling error from one generation to next in a finite population

Effect of genetic drift

Minimal in large populations whereas maximum in small ones

Genetic Drift aroses b/c

Founder effect and bottleneck effect

Genetic Drift

The random change in allele frequencies simply as a result of chance due to sampling error from one generation to next in a finite population

Effect of genetic drift

Minimal in large populations whereas maximum in small ones

Genetic Drift aroses b/c

Founder effect and bottleneck effect

Bottleneck effect

Population drastically reduces to a significantly smaller size in a short period of time

Genetic Drift

The random change in allele frequencies simply as a result of chance due to sampling error from one generation to next in a finite population

Effect of genetic drift

Minimal in large populations whereas maximum in small ones

Genetic Drift aroses b/c

Founder effect and bottleneck effect

Bottleneck effect

Population drastically reduces to a significantly smaller size in a short period of time

Founder effect

A new population develops by a few members of the original large population

Genetic Drift

The random change in allele frequencies simply as a result of chance due to sampling error from one generation to next in a finite population

Effect of genetic drift

Minimal in large populations whereas maximum in small ones

Genetic Drift aroses b/c

Founder effect and bottleneck effect

Bottleneck effect

Population drastically reduces to a significantly smaller size in a short period of time

Founder effect

A new population develops by a few members of the original large population

Mutations are

Random, non-directional and non-adaptive

Genetic Drift

The random change in allele frequencies simply as a result of chance due to sampling error from one generation to next in a finite population

Effect of genetic drift

Minimal in large populations whereas maximum in small ones

Genetic Drift aroses b/c

Founder effect and bottleneck effect

Bottleneck effect

Population drastically reduces to a significantly smaller size in a short period of time

Founder effect

A new population develops by a few members of the original large population

Mutations are

Random, non-directional and non-adaptive

Adaptive mutation

Under some circumstances E. coli are able to mutate in a directed way