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50 Cards in this Set
- Front
- Back
hypothesis
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suggested explanation, open to falsification, testable-scientific method
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negative controls
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expect to fail. controls for false positives
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positive controls
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expect to succeed controsl for false negativest
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transcription
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RNA to protien
1. dna unwinds 2. RNA polymerase binds to promotor 3. RNA polymerase "reads" base and inserts nucleotides 4. RNA polymerase "slides down" the DNA chain 5. repeat 3-4 until it hits end and falls off. |
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translation
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DNA to RNA
1. ribosomes binds to RNA start codon 2. ribosomes reads one codon triplet 3. one amino acid is added to teh amino acid in the chian 4. ribosome "slides down" the chain 5. repeat 2-4 until the stop codon |
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DNA
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deoxyribonucleic acid-base, sugar(deoxyribose), phosphate group. stores information becuase: -stable, its able to store infomration, compact, editable, able to dupicat, regulation mechanisms
chain of nucleotides; g, c, a, t |
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RNA
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AUCG evolved from early life, more control, RNA does a lot of things too
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gene
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basic physical and functional unit of heredity, instructions to make protiens, made of DNA, inherited
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promoter
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recognized by RNA polymerae, serves several functions: where to start, when to make it, how much/ how fast to make, under what conditions to make it
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genome
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total set of genes carried by a cell/ individual
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chromosome
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self replication genetic structures which contain cellular DNA
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euchromatin
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lightly packed
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heterochromatin
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tightly packed
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operons
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certain sugars bind to inhibitor and pulls off inhibitor allowign the bactieria to make enzymes allowing the body t metabolize allowing the sugars
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negative feedback
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blocks the process of trasncription or translation so it cant finisha nd create a cell
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mutation
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changes in base pair sequence
-germline- happens early on -somatic-damaged DNA eg. sunburn |
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sexual reproduction
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meiosis: forms gametes
fertilization: form zygote |
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homologus pairs
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not identical
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sister chromatid
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are identical
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non-sister chromotids
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not identical
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bacterial conjugation
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not really sexual reproduction, dna shared through pilus, can result in tranfser of antibiotic resistance virulence
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translocation
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pieces of chromosome switch
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inversion
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chromosome piece breaks and flips
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aneuploidy
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makes mroe chromosome than necessary
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polygenic disorders
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multiple genes, environmental factors, heart disease, high blood presure, alzheimers disease, arthritis, diabetes, cancer, and obesity
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mitochondrial disorders
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caused by mutation in mitochondrial DNA
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blending model
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offspring are a blend of the parents, the blend of characterisitcs is passed on to the next geneartion, variation is washed out over time.
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principles of inheritance (mendel)
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1segregation, pairs of alleles segregate into seperate gametes, each gametes contributes 1 alleles, phenotype is dominate trait
2independent assortment, alleles contribute 1 trait, all alleles are independent |
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incomplete dominance
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intermediate phenotype
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codominance
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blood type, A, B, I bother alleles are expressed at on etime
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multiple alleles
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alleles with multiple on one chromosome both expressed
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pleiotropy
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one gene cotnrols multiple traits
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epistatsis
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ex. albinism. one gene indirectly affects another
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allele
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one form or coding of a gene
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locus
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site on a chromsoome where agene is located
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genotype
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two alleles, one is dominate one is recessive, genotype directs phenotype
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phenotype
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observable trait, cannot always determine denotype by observing phenotype
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rule of multiplication
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probability of two or more independent events occuring together, "and", slimmer chance
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rule of addition
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probabily of events occuring if there are multiple ways of succeeding, "or", "better chance"
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autosomal dominant
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DD and Dd have disease phenotype, only dd genotypes are disease free, assumes no new mutations( for all, not just A dom), affected offspring never born to unaffected parents
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autosomal recessive
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only 'rr' gentotypes are affected, typically not seen in every generation. affected offspring can be born to unaffected parents
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lamarack theory
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simplest forms of life arose spontaneously. progressive change- a ladder or scale of nature. need drove change. inheritance of aquird characterisitcs
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natural selection
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left unchecked, members of any species increase in number, as numbers increase resources are consumed, scarcity and competition, survival of the few- individuals bearing favorable charactiristics
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fitness
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survival or mortality selection, mating success or sexual selction, family size or fecundity selection
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stablizing selection
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favors intermediate phenotype, extremes are disadavation, birth weight
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directional selection
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favors one end of phenotype, usually during environmental change, pepper moth
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diversifying selection
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favors borth extremes, usually during environmental changes,
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balancing selection
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maintians balance between advantagesous and disadvantageous alleles, sickle cell anemia
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frequency dependence selection
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type of frequence dependent on selction. postiive fitness increases as population increases, negative- fitness decreases as it becomes common
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protobionts
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spontaneous, abiotically production of organic molucules, concentrate molecules to allow chemical reaction such as polymarization
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