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23 Cards in this Set
- Front
- Back
3 d's of geriatric neuropsychiatry
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Demetia = psychiatric and cognitivce
Delirium = abrupt onset of cognitive loss Depression |
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Demetia-related illness that affects younger people with more personality and behavioral problems?
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frontotemporal dementia (FTD)
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amyloidopathy
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AD
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synucleinopathy
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diffuse lewy baody dementia (DLBD) (associated with PD)
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tauopathy
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FTD & progresive supranuclear palsy (SPS)
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Basalis of Meynert
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Cholinergic (damaged in AD)
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Raphe nuclei
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serotonin
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Ventral tegmental area
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dopaminergic
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Lewy Body
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PD & DLBD
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Picks bodies
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FTD
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Loss of posterior columns & spinocerebellar pathways
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Friedreich's ataxia
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Must have a cognitive problem which involves more than 1 cognitivie domain
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dementia
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first thing to go in dementia?
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loss of instrumental daily activities
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depression is very frequent in this dementia disorder
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mild cognitive impairment (MCI)
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Compulsions and disinhibitions are very frequent in this dementia disorder
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FTD
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partients have no evidence of forming a memory trace
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amnestic prodrome (AD!)
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3 key characteristics of DLBD
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1)Parkinsonism
2)fluctuations in alertness/cognition 3)visual ahllucinations -not as severe an amnestic problem as AD; more problems in teh visu-spatial and executive functions |
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Semantic dementia aka?
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Fluent aphasia - loss of word meaning
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FTLD can be caused by ?
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Tau derangements - Picks bodies & Tangles
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with Vit B12 check for increase in?
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MMA & homosystine
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in young people w/AD think
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pre-senilin-1 gene mutation
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In AD (vs. MCI)
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-involves more anterior cingulated gyrus
-lateral pariteal lobes involved -frontal lobe reduction in metabolism |
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Treatment for dementia
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Vit E, Curcumin, Fish oil extract
Cholinesterase inhibitors & NMDA receptor antagonists |