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23 Cards in this Set

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3 d's of geriatric neuropsychiatry
Demetia = psychiatric and cognitivce

Delirium = abrupt onset of cognitive loss

Depression
Demetia-related illness that affects younger people with more personality and behavioral problems?
frontotemporal dementia (FTD)
amyloidopathy
AD
synucleinopathy
diffuse lewy baody dementia (DLBD) (associated with PD)
tauopathy
FTD & progresive supranuclear palsy (SPS)
Basalis of Meynert
Cholinergic (damaged in AD)
Raphe nuclei
serotonin
Ventral tegmental area
dopaminergic
Lewy Body
PD & DLBD
Picks bodies
FTD
Loss of posterior columns & spinocerebellar pathways
Friedreich's ataxia
Must have a cognitive problem which involves more than 1 cognitivie domain
dementia
first thing to go in dementia?
loss of instrumental daily activities
depression is very frequent in this dementia disorder
mild cognitive impairment (MCI)
Compulsions and disinhibitions are very frequent in this dementia disorder
FTD
partients have no evidence of forming a memory trace
amnestic prodrome (AD!)
3 key characteristics of DLBD
1)Parkinsonism

2)fluctuations in alertness/cognition

3)visual ahllucinations

-not as severe an amnestic problem as AD; more problems in teh visu-spatial and executive functions
Semantic dementia aka?
Fluent aphasia - loss of word meaning
FTLD can be caused by ?
Tau derangements - Picks bodies & Tangles
with Vit B12 check for increase in?
MMA & homosystine
in young people w/AD think
pre-senilin-1 gene mutation
In AD (vs. MCI)
-involves more anterior cingulated gyrus

-lateral pariteal lobes involved

-frontal lobe reduction in metabolism
Treatment for dementia
Vit E, Curcumin, Fish oil extract

Cholinesterase inhibitors & NMDA receptor antagonists