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8 Cards in this Set
- Front
- Back
What is a pheochromocytoma?
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Functional and often maligmant tumor of the adrenal medullary chromaffin cells
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Which adrenal gland is affected most with pheo?
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R adrenal
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What do medullary chromaffin cells produce (aka pheos)?
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NE and epinephrine
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Signalment of pheochromocytoma?
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Older animals
Generalized weakness/lethargy M>F |
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In exam room - C/S that should make you think of pheochromocytomas?
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tachycardia
weakness hypertension - hemorrhage or retinal detachment |
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How are pheochromocytomas diagnosed?
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U/S
CT/MRI Genrall there is no calcification of the adrenal glands. |
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What labratory test should be performed if a pheo is a DDX?
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blood pressure
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TX for pheocromocytoma?
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1. SX - complications common - 31% mortality rate
2. lysodrin/mitotane - ineffective for adrenal medullary masses 3. phenoxybenzamine - block alpha adrenergic response to E & NE (causes vasodilation and hypotension). |