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59 Cards in this Set
- Front
- Back
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What ticks spread RMSF
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rhipicephalus sanguineus (brown dog tick) haemaphysalis (brush tick) amblyomma americonium (Lone star tick) |
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What in general does RMSF cause |
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What is the causative agent of RMSF |
Rickettsia rickettsii |
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Besides neurological and vascular signs, what C/S can RMSF show |
anorexia depression mucopurulent ocular discharge coughing V/D muscle pain |
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What type of neurological signs can RMSF show?
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ataxia vestibular signs stupor seizures coma |
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What is the most prominent clinical findings with RMSF
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poorly localizing joint/muscle/or neurological pain |
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What type of bleeding C/S can be seen with RMSF?
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melena hematuria retinal hemorrhages |
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What can be seen in male dogs with RMSF?
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scrotal edema hyperemia hemorrhage epididymal pain |
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What laboratory signs is the most consistent finding with RMSF? |
thrombocytopenia - mild |
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What biochemical changes/CBC can occur with fulminant RMSF?
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severe anemia severe leukopenia severe thombocytopenia |
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Due to vasculititis, what abnormalities can be noted on biochemical tests/chemistry with RMSF
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low proteins azotemia hyponatremia hypocalcemia bilirubinemia/bilirubinuria |
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How can RMSF be diagnosed?
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serology (IFA 4x increase) PCR |
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TX for RMSF
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doxycycline enroflaxin caution with fluid therapy and vasculitis |
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What occurs after recovery of infection with immunity from RMSF?
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probably life long |
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What do typical Ehrlichia diseases cause
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esp thromobocytopenia |
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What ticks carry ehrlichiosis
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Amblyomma americanum (texas lone star) |
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What are C/S of ehrlichiosis during the acute phase?
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anorexia fever weight loss ocular/nasal discharge lymphadenopathy edema of the scrotum/limbs |
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How long until the acute phase of ehrlichiosis resolves
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transient and resolve in 1-2 weeks w/o TX
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How long until the thrombocytopenia/leukopenia occur post ehrlichiosis infection
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10-20 d post infection |
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What doesn't occur despite severe thrombocytopenia with Ehrlichoisos
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hemorrhages |
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What other disease can C/S mimic for the acute phase Ehrlichiosis? |
RMSF |
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What are C/S of chronic phase of ehrlichiosis
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but can have: bleeding tendencies uveitis severe weight loss abd tenderness neuro signs |
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This echrlichoisis species causes neurological dysfunction, lamenss, arched back posture, reluctance to rise, joint swelling and pain. |
E. ewingii |
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These ehrlichiosis species morula are found in monocytes |
E. canis E. chaffeensis |
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This echrlichoisis species causes neurological dysfunction, lamenss, arched back posture, reluctance to rise, joint swelling and pain. |
E. ewingii |
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___ is elevated in 50-75 % of E. canis seropositive dogs |
serum proteins (hyperglobulinemia) |
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What can a E. canis infection be confused with this neoplasia due to
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due to a monoclonal gammopathy |
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What type of hyperglobulinemia is generally seen on serum protein electrophoresis with ehrlichiosis
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monoclonal or polyclonal |
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Why can dogs with E.canis develop hypoalbunemia
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(possibly reversible) |
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How can Echrlicosis be diagnosed (list) |
- ELISA/IFA (indicate exposure) - PCR amplification of the organisms |
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How is Echrlicosis definitively diagnosed?
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PCR amplification |
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What type of immunity does a previous infection with echlichiosis cause |
- can get disease recurrence, generally less severe |
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TX for Ehrlichia
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Why cannot enrofloxin be used to TX echrlichia
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suppress the infection and may result in clinical and hematological improvement, but does not eliminate the infection |
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How long after TX is improvement noted with ehrlichia
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24-48 hours |
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What echrlichia species infect people |
E. ewingii |
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What organism causes canine anaplasmosis
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anaplasma phagocytophilum |
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What ticks spread anaplasmosis
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Ixodes scapularis(deer tick) |
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What are the resevores for anaplasmosis
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small rodents (white footed mouse) |
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This tick born disease is most common in the fall
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anaplasmosis |
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C/S of anaplasmosis
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reluctance to more lymphopenia thormobcytopenia hypoalbuminemia |
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Where are anaplasma morula found |
neutrophils |
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C/S & biochem changes of anaplasmosis
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fever reluctance to more lymphopenia thormobcytopenia hypoalbuminemia |
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TX for anaplasmosis |
tetracycline |
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What organism causes canine cyclic thrombocytopenia
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A. platys |
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This tick born disease is considered minimally pathogenic
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A. platys |
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What complete blood count abnormalities does A. platys cause
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cyclic bacteremia causing thrombocytopenia q 10-14 d |
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What cells does A. platys infect?
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platelets (single to multiple basophilic inclusion) |
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A. platys is commonly co-infected with this organism |
possibly intensify the clinical disease of E.canis |
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TX for A. playts |
doxy tetracycline |
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Why should caution be used in determining a disease is solely due to A/ platys
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experimental studies have not identified abnormal clinical signs associated with A. platys infection
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What organism causes "atypical canine ehrlichosis"
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What tick born diseases can cats potentially acquire
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anaplasmosis Neorickettsia |
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What type of bacteria are bartonella species
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gram negative |
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Where do bartonella generally live and cause a
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long lasting RBC bacteremia |
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What is the organism causing canine bartonellosis
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bartonella vinsonii |
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What C/S occur with dogs with bartonellosis
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cutaneous vasculitits uvetitis polyarthritis IMHA thrombocytopenia (50% of dogs) |
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DX canine bartonellosis
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serology and PCR antibodies in a sick dog provides strong evidence for prior exposure/potentially active infection Titer >64 |
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TX for canine bartonellosis
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macrolides - MC doxycycline - high dose aminoglycosides - endocarditis |
