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32 Cards in this Set

  • Front
  • Back
T or F, most diabetic patients do not heal properly due to vascular reasons?
False, pecoraro study showed only 10% were vascular, most had neuropathic problems that allowed minor trauma>ulcer>faulty healing and amputation
The single most risk factor for developing foot ulceration is?
Loss of protective sensation
Why is NIDDM not a good acronym for type II diabetes?
Some patients with type II actually require insulin
Type 1 diabetes is also known as?
Juvenile onset diabetes and accounts for only 5% of diabetes diagnosis
Fasting plasma glucose greater or equal to ______
signifies diabetes as well as a a random plasma glucose of greater than or equal to _______
126mg/dL
200mg/dL
Pre-diabetes fasting and random plasma glucose ranges are?
Fasting = between 100mg/dL and 126mg/dL
Random = between 140mg/dL and 200mg/dL
4 main risk factors for developing type II diabetes?
obesity (central obesity especially)
family hx (1st degree relative)
habitual physical inactivity
age
T or F, metabolic syndrome is a problem with insulin resistance and hypoinsulinemia?
False, hyperinsulinemia
b/c your not able to uptake insulin, your body overproduces insulin leading to high amts of glucose in the blood, eventually the insulin runs out
T or F, increased insulin resistance and reduced beta production of insulin occurs the older we get?
true
Explain Advanced Glycation End products or AGE's
Hyperglycemia alters the structure and function of
protein; causing the cross-linking and thickening of
protein molecules
Even modest hyperglycemia results in the significant accumulation of AGEs
This occurs with an uptake of glycosulated LDL, a thickening and stiffening in the VESSEL WALL and an accelerated atherosclerosis
Macroangiopathy
This is associated with a thickening of the CAPILLARY basement membrane and CAPILLARY occlusion especially in the kidney, retina and microvasculature of peripheral nerves
Microangiopathy
Microvascular disease can lead to?
to polyneuropathy, kidney failure, blindness and inhibits the access of phagocytic cells and antibiotics to sites of infection
Cross-linking of periarticular collagen proteins caused by AGE's leads to?
joint stiffness and limited joint mobility
HbA1c is a measure of what?
glycated hemoglobin
tells the physician how well the pt has controlled blood sugar over 3 months
good glycemic control = HbA1c < 6.5%
Nonlocalizing foot pain (burning, especially at rest or at night)
Loss of sensation (insidious (pt’s don’t realize, distal, progessive)
Dry skin
Muscle weakness
“Nonantalgic” gait
Deformity (such as claw toes, foot drop)
and Loss of balance are all signs of?
Neuropathy in the foot
_______is the primary factor in diabetic foot ulceration.
sensory loss
The normal foot should be able to feel a _____gram filament
1 gram
can't feel 10gram, at risk for ulcers
Name 3 mechanisms of injury for the insensate foot:
Single High Stress
Constant Low Stress
Repetitive Stress
Infection
Heat/Cold/Chemical
When bed rest causes a pressure sore or one toe hits the other in a tight shoe, this is an example of?
constant low stress
If you notice layers of callus around a foot wound, what is probably the mechanism of injury?
repetitive walking stress
T or F, infection causes ulcers?
False, ulcers get deeper and develop osteomylitis b/c of infection but its not the cause
Foot ulcerations occur over areas of _______________.
highest pressure
foot deformity and joint limitation are often associated w/ _____________ and plantar ulceration.
high foot pressure
Pressure =
force (body weight)/foot area
Skin temperature measurement is useful in identifying areas of __________
high foot stress and in predicting future ulceration or charcot fracture
A ____ or greater skin temp diffference between feet may indicate the possibility of ulceration.
4
With claw toe formation, you will often see ulcers develop on _____________.
the tips of toes,
these benign looking wounds often lead to ostomylitis
Hammer toe formation will often lead to corns on the ________________.
dorsal surface of toes
Limited joint mobility can often be due to ___________
sensory loss
If someone is hypermobile in dorsiflexion and limited in plantar, they are risk of developing_________
heel ulcers
A charcot foot is an osteoarthropathy that involves the bone and joints giving the foot a characteristic _________ shape
rocker bottom