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29 Cards in this Set
- Front
- Back
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Estrogens
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Estradiol
Ethinyl estradiol Diethylstilbesterol |
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Medroxyprogesterone
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Progestin
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Levonorgestrel
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Progestin
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Megestrol Acetate
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Progestin
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Norethindrone
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Progestin
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Nogestrel
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Progestin
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Naldrolone
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Anabolic Steroid
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Oxandrolone
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Anabolic Steroid
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Action of Anabolic Steroids
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Weight gain
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Methyltestosterone SE
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Cholestatic Jaundice
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Diethylstilbesterol SE
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Vag adenoCA in daughters
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Clomiphene Class & action
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Antiestrogen
Stimulates ovulation |
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Clomiphene MOA
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Selectively blocks E-receptors in pituitary--> complex alters E-responsive gene expression--> decrease neg feedback
Antag @ hypothalamus; weak Agonist @ ovaries |
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Fulvestrant Class/Action
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Pure Antiestrogen
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Tamoxifen Class
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Anti-estrogen
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Tamoxifen Action
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Inhibits breast cell prolif
Decreases bone resorption Endometrial hyperplasia |
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Tamoxifen MOA
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Binds ER and alters gene response
Antag in breast Agonist in bone and uterus |
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Tamoxifen SE
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Menopausal symptoms,
Edema Endometrial hyperplasia Cancer |
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Raloxifene Class
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Anti-Estrogen
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Raloxifene Action
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Inhibits breast cell prol
Decreases bone resorption |
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Roloxifene MOA
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Antag in breast and uterus
Agonist in bone |
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MIfepristone Class
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Progesterone Receptor
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MIfepristone Action/MOA
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Abortifacient
Progestin & Glucocorticoid receptor Antagonist |
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Ulipristal Action
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Emergency Contraception
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Ulipristal MOA
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Progesterone Agonist & Antagonist
Block or delay ovulation or delay maturation of endometrium |
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Aromatase inhibitors
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the TROZOLEs( Anatrozole and letrozole)
Exemestane |
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Aromatase inhibitor Action
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Inhibit E synthesis
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Difference between TROZOLES and Exemestane MOA
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TROZOLES are competitive inhibitors while Exemestane is and irreversible inhibitor
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Raloxifene SE
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DVT
PE Hot flash |
