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35 Cards in this Set

  • Front
  • Back

Structural Causes of oropharyngeal dysphagia

Cervical Osteophytes - high dysphagia


Cricoid webs - HIgh dysphagia


Zenker diverticulum - Aspiration, regurg foul smelling food


Thyromegaly

Neurologic/Myogenic causes of oropharyngeal dysphagia

ALS


CNS tumor


Stroke


MD


Myasthenia Gravis


Parkinson disease


Demntia


Sjogren syndrome

Structural Causes of esophageal dysphagia

Dysphagia lusoria


Epiphrenic/Traction diverticulum


Esophageal strictures


Eosinophilic esophagitis


Esophageal webs or rings


Neoplams

Motility disorders associated with esophageal dysphagia

Achalasia


Diffuse esophageal spasm


Scleroderma

Factors associated with reflux

Cigarette smoking


Large meals


Eating late at night


EtOH


Chocolate


Citrus furits


Coffee


Fatty and fried foods


onions


perppermint

Medications associated with reflux

Anticholinergic agents


ASA and other NSAIDs


CCBs


Nitrates


Progesterone

Odynophagia

Symptom of esophageal ulceration


Usually caused by infectious esophagitis or pill-induced esophagitis


Test with upper EGD

What causes achalasia

Degeneration of the myenteric plexus resulting in loss of inhibitory neurons in the LES

Primary presenting symptom of alchalasia

Chest pain secondary to simultaneous esophageal wall contractions

Findings of CXR of alchalasia

dilated esophagus with air/fluid level

How to screen for alchalasia

Barium swallow with birds beak appearance


Confirm with manometry

What is pseudoachalasia

Obstruction of the LES secondary to malignant lesion

When to perform EGD for suspected alchalasia

To exclude mechanical obstruction

Treatment of choice for alchalasia

Surgical myotomy is first line


Nissen fundoplication (second line)


Neumatic dilatationif not a surgical candidate


Botox is last line


Nitrates and CCB are not recommended

How to diagnose diffuse esophageal spasm

Manometry with intermittent, high amplitude (>30 mmHg), simultaneous, nonperistaltic contractions in response to swallowing.

What is "corkscrew esophagus"

Caused by multiple simultaneous contractions on barium swallow


Characteristic of diffuse eso spasm

Treatment for diffuse eso spasm

CCB is first line


trazodone and imiptramine show improvement in small studies


BoTox as last resort

hypomotility syndromes occur most frequently in what setting

GERD

What is the treatment of hypotonic motility disorders

controlling acid reflux



Can fundoplication be performed on patient's with hypotonic motility disorders

No. would make dysphagia worse afterwards

What is scleroderma esophagus

aperistalsis of the esophageal body and hypotensive lower esophageal sphincter

Common organisms that cause infectious esophagitis

Candida albicans


HSV


CMV

What class of medications put immunocompetent patient's at risk for atypical eso infections

swallowed aerosolized corticosteroids

What are some atypical infectious causes of esophagitis

HPV


Trypanosoma cruzi


Myco tuverculosis


Treponema pallidum

What infection causes isolated esophageal ulcers

CMV

What infection causes multiple esophageal ulcers

HSV

Treatment of CMV esophagitis

ganciclovir

Treatment of HSV esophagitis

Acyclovir

What medications commonly cause pill esophagitis

Tetracycline


Fe


Bisphosphonates


K-Dur


NSAIDs


Quinidine

If medications that commonly cause pill esophagitis have to be given how can esophagitis can be avoided

Large bolus of water


Avoid recumbent posture for 30-60 minutes after ingestion

How does Eosinophilic esophagitis present

solid-food dysphagia


food impaction

What risk factors are associated with eosinophilic esophagitis

Asthma


Systemic and seasonal allergies


Males

How is eosinophilic esophagitis diagnosed?

>15 eos/hpf AND exclusion of GERD

How and why must GERD be excluded before diagnosing eosinophilic esophagitis

GERD can actually cause EE


Failure to improve with 6 weeks of PPI or perform ambulatory pH monitoring

Treatment of Eosinophilic esophagitis

swallowed aerosolized corticosteroids usually works well


Refractory disease may need eso dilation, systemic corticosteroids or food elimination diet