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59 Cards in this Set
- Front
- Back
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Ingestion of onions by any species results in what type of anemia?
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Heinz Body Anemia
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heinz body anemias are often seen in conjunction with what other erythrocyte morphology change?
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heinz body anemias are often seen with eccentrocyte RBCs
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what should you be looking for on a blood smear of cat who you suspect to have ingested acetaminophen?
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heinz body formation/heinz body anemia
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what should you be looking for on a blood smear of cat who you suspect to have ingested onions?
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heinz body formation/heinz body anemia
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what should you be looking for on a blood smear of cat who you suspect to have ingested propylene glycol?
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heinz body formation/heinz body anemia
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what should you be looking for on a blood smear of dog who you suspect to have ingested multiple pennies and has been unable to pass them?
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heinz body formation/heinz body anemia ---- due to zinc toxicosis
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what diseases in cats tend to lead to the formation of heinz bodies in the RBCs?
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lymphoma
hyperthyroidism diabetes |
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which 2 breeds of dog have hereditary stomatocytosis?
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Alaskan Malamutes
Miniature Schnauzers |
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how does a horse acquire hienz body formation on their RBCs?
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ingestion of WILTED red maple leaves or phenothiazines
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if you see a significant amount of basophilic stipling, what should you be thinking?
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lead poisoning
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T/F: increased heinz body formation will artificially increase the MCHC.
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true
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What happens to a horse if it eats wilted red maple leaves?
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heinz body Formation/ severe hemolytic anemia and usually death
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when do you se howell-jolly body formation?
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normally seen with regenerative anemias
seen in animals with nonfunctioning spleens or those that have had splenectomies seen with increased corticosteroids |
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When is basophilic stipling normal?
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in ruminants (especially in ruminants with a regenerative anemia)
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how does basophilic stipiling appear in the RBC?
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will see small basophilic granules within the RBC --- they are abnormal aggregation of ribosomes
normal in ruminants |
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when may you see basophilic stipling in dogs and cats?
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may see basophilic in dogs and cats with very regenerative anemias
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what 2 things should make you be thinking about lead toxicosis?
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a large amount of basophilic stipling
if the amount of howell-jolly body formation or too many nucleated RBCs is out of proportion with the anemia that is present |
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when do you see increased formation of nucleated RBCs?
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normally seen with regenerative anemias
seen in animals with nonfunctioning spleens or those that have had splenectomies seen with increased corticosteroids |
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what is the most common blood parasite you will see in cats?
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Mycoplasma haemofelis
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T/F: when an animal has mycoplasma haemofelis, it is that parasite that is causing the anemia.
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FALSE -- it is not the parasite that causes the anemia, it is the immune system that is reacting to the parasite that is causing the anemia.
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T/F: Mycoplasma haemocanis is almost never seen in animals that still have a spleen.
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TRUE
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T/F: Mycoplasma haemocanis is almost always seen in animals that still have a spleen.
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FALSE -- it is very rare to see mycoplasma haemocanis in animals with spleens --- more likely to see them in animals with no spleen or a non-functional spleen
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what will the RBC morphology typically look like in a splenectomized patient with Mycoplasma haemocanis?
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Spherocytes + Agglutination + Mycoplasma parasite
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Spherocytes + agglutination may suggest ...
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Mycoplasma haemocanis
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T/F: Cytauxzoon felis is usually fatal in cats.
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True
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a tear drop structure within the RBC should make you think?
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Babesia canis
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Rouleaux formation is normal in what species?
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horses
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Rouleaux formation in small animals is suggestive of ...
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increased globulin
--- commonly seen in dogs with Ehrlichia |
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agglutination of RBCs is suggestive of which disease?
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IMHA
suggests that antibodies are attaching to the RBCs |
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Cat + Macrocytic Anemia
suggestive of? |
suggestive of FeLV -- need to test for FeLV
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Dog + Acanthocytes
what should you be thinking? |
hemangiosarcoma
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Cat + Acanthocytes
what should you be thinking? |
hepatic lipidosis
need a liver aspirate |
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dog got bit by a rattle snake, what do you expect to see on his blood film?
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Eccinocytes
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dog got stung by multiple bees, what do you expect to see on his blood film?
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Eccinocytes
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Schistocytes + Thrombocytopenia =
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strongly suggestive of DIC
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what should you associate Keratocytes with?
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Fe Deficiency Anemia
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Spherocytes on a blood smear should make you think what 2 things?
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IMHA ****
Mycoplasma haemocanis -- does the animal have a spleen/a functional spleen? |
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Splenectomized dog
what should you be looking out for on the blood smear |
Spherocytes + Mycoplasma Haemocanis
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you see Eccentrocytes + heinz body formation on the blood smear of a cat. What do you think the cat may have ingested?
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onions
acetominophen |
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Bleeding Time - Prolonged
ACT - Prolonged APTT - normal PT - normal TT - normal what are these results suggestive of? |
Thrombocytopenia
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Bleeding Time - Prolonged
ACT - Prolonged APTT - Prolonged PT - normal TT - normal vWF - decreased what are these results suggestive of? |
von Willebrand Disease
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Bleeding Time - Prolonged
ACT - normal APTT - normal PT - normal TT - normal vWF - normal what are these results suggestive of? |
acquired platelet disfunction
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Bleeding Time - normal
ACT - Prolonged APTT - Prolonged PT - Prolonged TT - normal vWF - normal what are these results suggestive of? |
Rodenticide
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What is the most common cause of thrombocytopenia?
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secondary immune mediated
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what are the 2 things that typically cause a thrombocytopenia bc they decrease production of platelets in the bone marrow?
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Drugs (estrogen)
Infectious agents (Ehrlichia) Neoplasia (myelopathisis) Immune-mediated (megakaryocytes) |
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Platelets = <50,000
what do you expect to happen with a platelet count this low? |
increased bleeding will occur secondary to trauma
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Platelets = <10,000
what do you expect to happen with a platelet count this low? |
spontaneous bleeding
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what is the most common infectious cause of thrombocytopenia?
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Ehrlichia
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vWF complexes with which coagulation factor?
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Factor VIII
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Bleeding Time - normal
ACT - normal APTT - Prolonged PT - normal TT - normal vWF - normal what are these results suggestive of? |
something is wrong with the intrinsic pathway
likely an inherited disorder -- Factor VIII def resulting in Hemophilia A |
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Hemophilia A is caused a deficiency in what coagulation factor?
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Factor VIII
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Hemophilia B is caused a deficiency in what coagulation factor?
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Factor IX
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severe bleeding occurs in patients with Hemophilia A or B?
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Hemophilia B
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Variable bleeding occurs in patients with Hemophilia A or B?
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Hemophilia A
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Bleeding Time - normal
ACT - normal APTT - normal PT - Prolonged TT - normal vWF - normal what are these results suggestive of? |
implies that the common pathway is not involved and .: Factor VII on the extrinsic arm is the problem
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Bleeding Time - normal
ACT - normal APTT - Prolonged PT - Prolonged TT - normal vWF - normal what are these results suggestive of? |
implies there is a problem with both the extrinsic and intrinsic arm -- possible rodenticide/something affecting Vitamine K dependent factors
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Bleeding Time - normal
ACT - normal APTT - normal PT - normal TT - Prolonged vWF - normal what are these results suggestive of? |
DIC
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Bleeding Time - normal
ACT - Prolonged APTT - Prolonged PT - Prolonged TT - normal vWF - normal what are these results suggestive of? |
implies there is a problem with both the extrinsic and intrinsic arm -- possible rodenticide/something affecting Vitamine K dependent factors
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Bleeding Time - Prolonged
ACT - Prolonged APTT - Prolonged PT - Prolonged TT - Prolonged FDPs - Increased D-dimers - increased Fibrinogen concentration - decreased what are these results suggestive of? |
DIC
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