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266 Cards in this Set

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Describe the cellular malfunction that occurs in shock.
Oxygen consuption exceeds delivery from bloodstream. Ischemia results, and cells start metabolizing anaerobically, producing lactic acid byproducts. Inflammatory mediators and free radicals accumulate

Acidosis plus hypotension plus cell death
Give 3 examples of obstructive shock
1. Massive PE
2. Tension PTX
3. Cardiac tamponade
4. Aortic stenosis
5. Air embolism
What is the most common type of distributive shock?
Name the 3 others.
1. Septic
2. Anaphylaxis
3. Drugs/Poisoining
4. Neurogenic
Name 2 conditions in which you would see pulsus paradoxus.
(change in pulse strength with respirations:weaker with inhalation)

1. Asthma
2. Cardiac tamponade
What numbers change in positive orthostatic hypertension?
SBP drops >20
HR increases >30
Kussmaul's sign
paradoxical swelling of neck veins with inspiration

1. right ventricular dysfunction
2. impaired venous return
3. Tension PTX
4. Massive PE
Cullen's sign
periumbilical ecchymosis

1. ectopic pregnancy
2. hemorrhagic pancreatitis
3. ruptured spleen
4. leaking AAA
Grey-Turner's sign
flank ecchymosis

1. hemorrhagic pancreatitis
2. leaking AAA
What murmur do you expect to hear with acute papillary muscle rupture?
Acute Mitral regurg.

Systolic murmur radiating to axilla
Name 2 reasons to check a quick bedside glucose in a suspected shock patient?
1. AMS
2. Children (20% of critically ill children were hypoglycemic)
Westermark sign
pulmonary oligemia
vasoconstriction distal to embolus, vasodilation proximal
Hampton's hump
wedge shaped consolidation
What is a normal urine output?
0.5-1cc/kg/hr
What are the ABCDEs of managing shock?
Airway
Breathing
Circulation
Disability (ie spinal cord injury)
Expose (undress and inspect pt)
How much fluid should you start for resuscitation in and adult? Child?
1-2L bolus

20cc/kg bolus

continually monitor for response
What is the 3:1 rule when using LR to replace fluid loss?
Only 30% of LR stays intravascular. Need to replace 3X the volume of blood lost.
What should you do if your attempts at fluid resuscitation do not improve your patient in shock?
consider ongoing/severe blood loss

order angiography or immediate surgical intervention
At what H/H should you consider blood transfusion?

How much will one unit improve the numbers?
Hgb<10
Hct<30

1 unit of blood raises Hgb by 1, Hct by 3
How much of the left ventricle is infarcted if the pt is in cardiogenic shock?
>40%
Name 3 medications commonly given for MI that will make hypotensive cardiogenic shock worse?
1. MSO4
2. NTG
3. Beta Blockers
Compare and contrast dopamine and dobutamine in the context of cardiogenic shock.
Dobutamine- improves contractility and diastolic coronary blood flow without huge increase in HR. Use for SBP >100

Dopamine-can produce a profound increase in HR and increased myocardial oxygen demand. Use the lowest dose possible! Use for SBP 70-100
Electrical alternans on EKG points to what cardiac cause?
Pericardial tamponade
What is a good empiric abx therapy for septic shock in the ER?
Ceftriaxone plus gentamicin
What can you give to increase SVR in the patient with persistent septic (distributive) shock after fluids fail to improve hypotension?
Vasopressors
-dopamine
-norepinephrine

(not dobutamine, which is cardiac specific)
Name the 3 most common causes of anaphylactic shock
1. Abx
2. Radiocontrast agents
3. Hymenoptera stings
What can you give for anaphylaxis besides epinephrine?
Antihistamines
1. diphenhydramine
2. Ranitidine
Corticosteroids
Albuterol
Glucagon (if pt is on BB)
What is the neurologic finding in neurogenic shock?
Unapposed vagal tone from disrupted sympathetic outflow. Acute.
What physical exam findings distinguish neurogenic shock from the others?
Skin is warm and dry (may need dopamine)
Bradycardia (may need atropine)
What can you do quickly to support the pregnant patient in shock?
Place mother in left lateral decubitus position, to take pressure off of IVC, increase return to heart.
How long does the maturation stage of wound healing last?
The scar changes from 24 days up to 1 year after injury
Name the first 3 stages of wound healing.
1. Inflammatory 0-3 days
2. Destructive, epithelialization 2-5 days
3. Proliferative, granulation 3-24 days
What factor has the most negative effect on wound healing in general?
INFECTION

also lack of blood supply, peripheral location
What local anesthetic should you use if you want the fastest numbing action?
Lidocaine (onset almost immediate,lasts 1-2 hours)

Bupivicaine (Marcaine)(onset 10 min, lasts 6-8hrs)
Name the areas where adding epinephrine to local anesthetics to control bleeding is contraindicated.
1. Fingers
2. Toes
3. Ears
4. Penis
What is the maximum adult dose of lidocaine (Xylocaine)?
30cc of 1% lidocaine sol.
Name 3 ways to decrease the pain of injecting a local anesthetic like lidocaine.
1. Inject slowly
2. Warm lidocaine
3. Mix in some bicarb to decrease burning sensation
If a pt is allergic to lidocaine, what can you use instead?
An esther formulation anesthetic, like procaine or tetracaine.

If the allergic agent is unknown, can use dilute diphenhydramine, though it hurts to inject and doesn't work as well.
What should you use to irrigate a wound?
Normal saline medium pressure is least toxic to tissue
Name 2 kinds of absorbable (internal) sutures.
Vicryl
Chromic
What is the maximum adult dose of lidocaine (Xylocaine)?
30cc of 1% lidocaine sol.
Name 3 ways to decrease the pain of injecting a local anesthetic like lidocaine.
1. Inject slowly
2. Warm lidocaine
3. Mix in some bicarb to decrease burning sensation
If a pt is allergic to lidocaine, what can you use instead?
An esther formulation anesthetic, like procaine or tetracaine.

If the allergic agent is unknown, can use dilute diphenhydramine, though it hurts to inject and doesn't work as well.
What should you use to irrigate a wound?
Normal saline medium pressure is least toxic to tissue
Name 2 kinds of absorbable (internal) sutures.
Vicryl
Chromic
Name 3 types of non-absorbable (external) sutures
1. Nylon
2. Prolene

3. silk-easy knot tying but highest tissue reactivity
When would you consider staples for wound closure?
Straight lesions in areas of low tension (scalp, knee)
How do you suture an ear injury?
Never suture cartilage. Align the cartilage and suture over it.

Drain perichondral hemorrhage and apply pressure dressing.
What is the role of deep sutures?
Reduce wound tension
Close dead spaces where fluid can collect
Contained fully in dermis
What should you do to treat a possible rabies exposure?
HRIG-rabies immune globulin
HDCV-active immunity (given at 0,3,7,14,28 days)
What is the rule of nines?
Documents percentage of body surface involved in burn.
Head-9%
Arm and hand-9%
Anterior trunk (bilat)-18%
What is the "cheater's" way to estimate total body surface area for burns?
The surface of your palm is about 1%
What degree burn is sunburn?
1st degree. Epidermal involvement only. no blisters, erythema blanches to pressure
If you see blisters, what is the most likely degree of burn?
2nd degree. "Superficial partial thickness" Epidermal and dermal involvement with sparing of follicles and sweat glands.
Define a deep partial thickness burn.
Deep dermis is involved, can be difficult to distinguish from full thickness burn. Skin appears waxy and white with red elements. Will likely scar.
What do you suspect when a pt presents to the ER with a severe burn that is painless?
Third degree burn, full thickness, all the way down to subcutaneous fat. Skin is pale, painless and leathery. Will not heal spontaneously unless extremely small. Need grafting.
What is a fourth degree burn?
So deep it involves muscle, tendon and bone. Potentially life threatening, worry about rhabdomyolysis, renal failure, hypovolemia, sepsis.
List 3 signs/sxs that indicate smoke inhalation injury has occured?
1. Singed nasal hairs
2. Carbonaceous sputum
3. Cough/stridor
4. Lacrimation
What is the Parkland formula?
Calculates fluid resuscitation needs after burn. Give LR from the TIME OF INJURY. Half over first 8 hours, the rest over the next 16

4mL x kg x %TBSA
When would you apply cool compress for a burn injury?
ASAP after burn. can reduce thickness of skin damage if applied within an hour of injury.
When would silver sulfadiazine (silvadene) be contraindicated in burn care?
Sulfa allergy
Pregnancy
Facial burn
How bad is the burn if you are considering admission to burn center for treatment?
Partial thickness >15% in adults, 10% kids
Full thickness >2%
Burns involving face, hands, feet, perineum
Circumferential burns
What should you do if your pt has not been vaccinated for HepB, and has just been blood exposed?
HBIG (immune globulin)
initiate HepB vaccination series
What temperature defines fever in the
1. 2mo child
2. >2mo child?
1. 38C (100.4)
2. 39C (102.2)
Why do we take fever in the neonate so seriously?
Inability to combat infection, bloodborne disease due to immaturity of reticuloendothelial system
When do we give the first round of immunizations to children?
2 months (HepB can be started at birth)

Until vaccinations are started, children are especially vulnerable.
What vaccines are recommended to start at 2 mo?
1. Rotavirus (1/3)
2. DTaP (1/5)
3. Hib (1/4)
4. PCV (1/4) (prevnar/pneumovax)
5. IPV (1/2)
6. HepB (1/3) if not already started at birth
It makes sense not to give a live, attenuated vaccine to children under the age of 12 mo because of a developing immune system. What live vaccines are started at 1 year of age?
1. Varicella (1/1 if under 12, 1/2 if older than 13)
2. MMR (1/2)
You find positive blood cultures in a well appearing child with a fever of 38.5C. You cannot find any focus of infection despite exhaustive search. What might be the diagnosis and how do you treat?
Occult bacteremia-usually transient and resolves without abx, however 1-3% chance of developing SBI.
When should you admit a child with a fever for further observation/evaluation?
Child is ill appearing
Child is under 36mo

requires full sepsis workup and admission
Quickly dose an anitpyretic for a 20kg child.
1. APAP: 10-15mg/kg q 4hr. (may give 30mg load in ER). =200-300mg q 4hr.

2. Ibuprofen: 5-10mg/kg q 6hr. =100-200mg q 6hr.
Always get a birth history when evaluating a febrile child under 2 years of age. Name 3 risk factors for neonatal sepsis.
1. Premature rupture of membranes
2. Low birth weight
3. Prematurity/Resuscitation at birth
What is paradoxical irritability, and what could it indicate?
Infant cries when handled, is quiet when left alone.

Could be a sign of nuchal rigidity, meningitis.
Why is evaluating the child aged 0-4 weeks old so difficult?
Physical exam unreliable
Very sick child may appear well
Fever may be only sign of SBI
Finding a minor focus of infection does not r/o SBI
You are seeing a 3 week old infant in the ER with a fever of 39C (102.2), and admit her for IV abx (mandated for 0-4 wks old). What 3 organisms are the most likely cause of her infection?
1. Listeria
2. E. coli
3. Group B Strep
It is no longer mandated to admit a febrile child aged 4-8 wks. After a FULL WORKUP for sepsis, what criteria can you use to decide whether to discharge the pt?
Rochester Criteria. All must be ok:
1. Full term, well appearing infant with no medical problems, no previous abx treatment.
2. WBC btwn 5-15,000
3. No WBCs on urinalysis or lumbar puncture
4. Nl CSF gram stain
5. Nl CXR
6. Reliable caregivers and follow-up.
What are the 2 most likely organisms to cause fever in the 4-8 week old child?
1. Strep pneumoniae
2. N. meningitidis
Give a good empiric abx therapy to cover sepsis in
1. 0-4 wk old
2. 4-8 wk old
3. 2-36 mo old
1. Amp/ceftriaxone or Amp/Gent
2. Ceftriaxone (plus Amp if need to cover for Listeria)
3. Ceftriaxone plus Vancomycin
Miosis

Mydriasis
pinpoint pupils

dilated pupils
You do a bedside accucheck glucose level on a pt that comes in to the ER with AMS. What should you do if it comes back <60?
Give 2mL/kg D50W IV
A 100mg IV dose of thiamine is given to help Wernicke's encephalopathy when the pt has evidence of long term alcohol abuse or malnutrition and what other symptom?
Any of the following:
Acute confusion
Decreased LOC
Ataxia
Opthalmoplegia
Memory disturbance
Hypothermia with hypotension
DTs
Name a few drugs that cause QT prolongation
Azithromycin
FQ
TCAs
Amiodarone
Antipsychotics
What does decontamination of the poisoned patient refer to?
Eye and skin contamination
and
Gastric emptying
Give an example of a substance the pt might be contaminated with that could be detrimental to the entire ER staff?
Pesticides
How long should you irrigate the eyes after chemical burn?
2L NS immediately, then check pH.

If alkali burn (worst and deepest), irrigate for 1-2 hours, until pH returns to normal (7)
Name the most serious and most common alkali contamination in the eyes.
Most serious- ammonia

Most common- lime
what is the average amount of fluid used for gastric lavage?

How much of the toxic substance can be removed?
2-3L

35-65%
Gastric lavage is only indicated in select situations. Name the indications
1. Very recent ingestion of potentially lethal substance (within 1 hour)

2. Lethal dose is not absorbed by charcoal
Name 2 substances that do not bind activated charcoal after ingestion.
Lithium
Iron
What is a clear indication for activated charcoal administration?
Ingestion of any drug know to adsorb to the charcoal
or
After unknown ingestion with protected airway
Name 2 cathartics you would use to DECREASE TRANSIT TIME THROUGH THE GUT
Sorbitol
Magnesium citrate
Name 3 contraindications to using a cathartic to minimize absorption of a toxic substance.
1. Ingestion of substance causes diarrhea
2. Children <5yo
3. Intestinal obstruction
4. Ingestion of caustic material
5. Renal dysfunction
What substance is used to do a whole bowel irrigation, and why doesn't it cause severe electrolyte imbalance?
Polyethylene glycol (GoLytely)

is osmotically balanced, does not cause fluid electrolyte shift
Name 3 indications for whole bowel irrigation.
1. Heavy metal ingestion: Li, Fe, Pb (don't bind to charcoal)

2. Body packers of drugs in condoms

3. Enteric coated or Sustained release medications
Making the urine alkaline by administering IV sodium bicarbonate will help to maximize elimination of certain intoxications. Name 3 substances this would work in.
1. Salicylates
2. TCAs
3. Methanol
4. Certain herbacides
5. Phenobarbital
Giving boluses of 1-2mEq/kg sodium bicarb will alkalinize the urine. How can you maximize this dose to continually infuse bicarb?
Continuous infusion of D5W and sodium bicarb at double the maintenance dose
Name 3 contraindications to alkalinizing the urine to help excrete toxins.
1. Renal dysfunction
2. Hypokalemia
3. Cannot tolerate volume or sodium overload
Hemodialysis to remove toxins is reserved for potentially life threatening substances that are not easily removed in other ways. Name 3 indications
1. Lithium
2. Theophylline
3. ethylene glycol
4. Methanol
5. Salicylates
Hemoperfusion, the extracorporeal filtration of blood through charcoal filter can remove protein bound toxins. What substance is it most useful for?
Barbituates


digitalis, methotrexate
Describe the 3 characteristics of the opioid toxidrome.
HEROIN/MORPHINE

1. Respiratory depression
2. Miosis
3. CNS depression to profound coma
What repiratory complication is often seen in opioid intoxication?
pulmonary edema
Why do you have a little extra time to give activated charcoal in opioid ingestion?
Decreases gastric motility/emptying
How often can you give doses of naloxone (narcan) to a pt with suspected opioid intoxication?
Up to 2mg q 2-3min 3 times.

is short acting, may need to retreat.
Describe the anticholinergic toxidrome.
Dry as a bone-decreased salivation
Hot as a hare-hyperpyrexia
Red as a beet-cutaneous vasodilation
Blind as a bat-mydriasis
Mad as a hatter-delirium

*may also be tachycardia, urinary retention, myoclonic jerking, decreased/absent BS
Name 3 common anticholinergic meds that cause anticholinergic toxidrome
1. Benztropine
2. Scopolamine
3. Atropine (eye drops with red tops)
Name 3 antihistamines that can cause anticholinergic toxidrome
1. Diphenhydramine
2. Chlorpheniramine
3. Promethazine
4. Hydroxyzine
5. Meclizine
TCAs, hallucinogenic mushrooms, antispasmodics and antipsychotics can all cause what toxidrome in overdose?
Anticholinergic
Describe the cholinergic or insecticide toxidrome
"SLUDGE BBB"
salivation
lacrimation
urination
defecation
gastric emptying
emesis
bradycardia
bronchospasm
bronchorrhea
Name 3 classes of substances that can cause the cholinergic/insecticide toxidrome
1. Organophosphates (irreversible inhibit cholinesterase)
2. Carbamates (reversible inhibit cholinesterase)
3. Cholinergic meds (physostigmine, green top eyedrops)
4. Nerve gasses
Name 4 treatment options when you observe the cholinergic/insecticide toxidrome.
1. 2PAMCl breaks down organophosphates and carbamates
2. Atropine for resp sxs
3. Furosemide for pulm edema
4. Diazepam for seizure
Describe the sympathomimetic toxidrome. What is the most common cause?
"total body overdrive"
-tachycardia, diaphoresis, mydriasis, psychosis
-later hyperthermia, hypertension, seizure, vascular accidents (cocaine)

cocaine
Name 3 drugs that can produce sympathomimetic effects.
1. Pseudoephedrine
2. Ephedra
3. Methamphetamines
4. Amphetamines
5. Cocaine
6. MDMA
7. PCP
Why are beta blockers contraindicated in pts with sympathomimetic toxidrome?
Unapposed alpha receptor stimulation
What is the number one cause of drug ingestion fatality?
TCAs
Name 3 possible findings on EKG in anticholinergic overdose.
1. sinus tachycardia
2. QRS prolongation (>100ms)-give sodium bicarbonate
3. Ventricular arrhythmias-give lidocaine
4. Narrow QRS supraventricular tachydysrrhythmias resulting in hemodynamic deterioration- give physostigmine over 2-5 min
Why can you give charcoal/maybe do gastric lavage in a pt with anticholinergic overdose hours after the ingestion?
Anticholinergic effects include delayed gastric motility
What are the caveats to administering physostigmine for seizure, dysrrhythmia or agitation to a patient with anticholinergic overdose?
Must get EKG beforehand

No prolonged PR interval
No prolonged QRS
Is hemodialysis indicated for anticholinergic overdose?
No, dialysis and hemoperfusion are ineffective.
what does physostigmine do?
the only reversible acetylcholinesterase inhibitor that directly antagonizes CNS manifestations of anticholinergic activity
-useful in intractable seizure
-useful in agitated delerium
-must have EKG checked before giving!
Describe the sedative toxidrome
1. Resp depression
2. Depressed mental status
3. Hypotension and hypothermia
What 2 substances are the most common causes of sedative OD?
1. BZDs
2. Barbituates

then GHB, GBL
How much of a sedative drug must a pt take to achieve severe toxicity? What are the early signs of overdose?
10X the hypnotic dose

Ataxia, incoordination
Nystagmus
Slurred speech
If you see skin lesions with a sedative toxidrome, what substance do you suspect?
Phenobarbital, barbituates

clear vesicles and bullae on erythematous base
Activated charcoal is indicated for all sedative intoxications except?
GHB and GBL
How is a barbituate ingestion treated differently for elimination from the body?
Alkaline diuresis
hemodialysis/hemoperfusion indicated
what is the antidote for BZD overdose?
what is the major risk with administering it?
Flumazenil

increases risk for seizure, get EKG first to make sure it wasn't a TCA OD.
Not as useful in a chronic BZD user
This poison is the leading cause of pediatric ingestion mortality. How are they classified?
Hydrocarbons
Toxic: halogenated and aromatics
Nontoxic:gas, kerosene, paint thinner, lubrication oil, etc.
Many body systems are hit by hydrocarbon ingestion. Which is the most serious?
1. Respiratory distress

CNS:decreased LOC, euphoria
CV:syncope, SCD
GI: N/V, sore throat
What abnormal lab findings might you expect in a hydrocarbon ingestion?
Leukocytosis within 48 hours
Anion gap acidosis
Hypomagnesemia, hypophosphatemia
Elevated LFTs
Decontamination of the GI tract is generally not recommended for hydrocarbon ingestion. What substances are the exception?
"CHAMP"
Camphor (can cause seizures)
Halogenated HCs (arrhythmia and hepatotoxicity)
Aromatic HCs (myelosuppression, malignancy, CNS toxicity)
M Heavy metals
Pesticides
When can you discharge the patient with a nontoxic hydrocarbon ingestion?
Must observe the pt for 6 hours!
Clean CXR
Good oxygenation
What are the main systems affected by TCA overdose?
Cardiac (arrhythmia-wide QRS, tachy, HYPOtension)
GI (anticholinergic effects, delayed emptying)
CNS (ataxia, confusion, hallucination)
RESP (pulm edema, ARDS, aspiration)
Why should you set mechanical ventilation to hyperventilate the pt with a TCA overdose?
Metabolic or resp acidosis
How do you treat a wide QRS dysrhythmia, as in TCA overdose?
1. Urinary alkalinization by administering bicarb via IV

2. second line therapy lidocaine
What is a toxic dose of APAP?
>140mg/kg in 24 hours
or
>7.5g in 24 hours
Name the 4 stages of APAP toxicity.
1. first 24 hours, minimal signs and sxs.
2. days 2-3, RUQ pain, tachycardia, hypotension, abnormal LFTs
3. days 3-4, fulminant hepatic failure, coagulopathy, encephalopathy
4. 4 days to weeks: recovery if survive stage 3
What is the antidote to APAP overdose?
When should it be given?
NAC (N-acetylcysteine/Mucumyst)

Anytime a level measured is above the toxicity line on the nomogram, or level in body is rising.
Check serial levels at 4,6,8 hours out from ingestion. Is 100% effecitve if given within 8 hours of ingestion
Describe the salicylate toxidrome.
Tinnitus
Tachypnea
Vomiting
Fever
AMS
Why is the pt with ASA overdose tachypnic?
Compensating for an anion gap acidosis. there is direct stimulation of respiratory drive centers by the salicylate

Remember to hyperventilate the pt when you intubate them to avoid acidemia
What are the main dangers with ASA overdose?
1.RESP-pulmonary edema, resp arrest
2.CARD-tachycardia, hypotension, dysrhthmia
3.GI-hemorrhage, perf, pancratitis, hepatitis
4.HEME-DIC
5.Hypokalemia (in response to metabolic acidosis and urinary alkalinization)
When monitoring a pt with ASA overdose, how often should you draw serum levels?
every 2 hours until ASA level drops
What is the best method for enhanced elimination of ASA in overdose?
Hemodialysis
Name some reasons for a high anion gap acidosis.
"MUDPILES"
methanol
uremia (renal failure with high BUN)
DKA
Paraldehyde
Iron and isoniazid
Lactic acid
Ethylene glycol and ethanol
Salicylates
Give 2 reasons for prerenal acute renal failure
1.Dehydration, volume depletion, redistribution of body fluids (ascites, shock)
2.Cardiac failure
Give 3 reasons for intrinsic ARF
1.Acute tubular necrosis (ATN)
2.Thrombosis, ischemia to renal tissue (TTP, DIC)
3.Poststreptococcal glomerulonephritis (PSGN)
Give 3 reasons for postrenal ARF
Obstruction in the urinary tract
1.Phimosis
2.Urethral stricture
3.Blood clots, stones, tumors
4.Prostatic hypertrophy
5.Neurogenic bladder
In what patient population is UTI most likely to lead to sepsis?
Neonates and elderly
When does UTI required a surgical consult?
In children under 4 years old
What organism is most implicated in UTI?
E.coli
Define UTI relapse
Define UTI reinfection
Relapse-same organism causes UTI within 1month

Reinfection-sxs recur during 1-6 month period
What is a complicated UTI
Pt has underlying renal or neurological disease
Some people have a genetic predisposition to UTIs, and women get more UTIs. Give 2 reasons
Bacteria in bladder increases 10x after sex
Loss of lactobacillus with age
Spermacide enhances growth of E.coli

Genetic uroepithelial E.coli binding glycolipids
What will pyuria show on microscopic U/A?
>10 WBCs per hpf with few or rare squamous cells

WBC casts
Name 3 risk factors for pyelonephritis
1. Renal calculi
2. Anatomic abnormality
3. Recent instrumentation
4. Prostatitis or Prostatic hypertrophy
What is the rule of 2s for pyelonephritis?
Deciding whether or not to admit the pt. Can go home if:
2L fluid
2 doses pain meds on board
2g ceftriaxone
fever drops 2 points
tolerates 2 glasses of water
2 weeks of reliable outpt treatment
What is the easiest way to determine whether a suspected scrotal abscess is localized to the scrotal wall or involves intrascrotal organs?
Ultrasound
Fournier's gangrene often causes a scrotal abscess. What caused this and how will you treat?
Start empiric broad abx therapy, is usually polymicrobial (G+/G-)
Consult urology
Starts from indroduction of bacteria through scrotal skin, urethra, rectum
What is the ER treatment for balanoposthitis?
Cleansing and antifungal cream. Do not break adhesions from reattatchment of foreskin.
What is the treatment for phimosis, or unretractable foreskin?
Circumcision
What is the danger with paraphimosis?
Glans edema and venous engorgement. Can lead to arterial compromise.
What must you do before discharging the child with a penile hair tourniquet?
Assure urethral integrity and distal penile blood flow.
What tissue tears during penile "fracture"?
How will you know?
Tunica albuginea
Penis will be swollen, discolored, tender
How is penile fracture treated?
Urology consult-they will come and evacuate hematoma, suture tunica albuginea back together.
What should you find on physical exam in a pt with Peyronie's disease?
Thickened dorsal plaque.

refer to urology.
What is dupuytren's contracture?
fixed flexion contracture of the hand, fingers cannot be fully extended.

Associated with Peyronie's disease
blue dot sign
how do you confirm the diagnosis?
torsion of the appendix testis

Doppler ultrasound
How do you treat torsion of the appendix testis?
Most calcify and degenerate in 2 weeks, surgery generally not necessary.
What is the most likely cause of epididymitis?
<40 yo STD- DOXYCYCLINE/ROCEPHIN
>50 urinary pathogen: E.coli, Klebsiella due to BPH or strictures. CIPRO/LEVAQUIN
What is "chemical" epididymitis, and who gets it?
Epididymitis in young boys secondary to retrograde reflux of sterile urine into tail of epididymis.
Describe 3 signs/sxs of epididymitis.
1. Testicular pain/swelling
2. Abdominal/inguinal canal pain
3. Pain relief with recumbent position
What dangerous condition can epididymitis left untreated progress to?
Epididymoorchitis or scrotal abscess.
Name a congenital anomaly that can predispose to testicular torsion. Which side is more likely to torse, and how do you fix it?
cryptorchidism, or undescended testis

LEFT
Anchor testis to gubernaculum
What age group of men is most likely to get testicular torsion?
Men <30. Peak age 12-18 years old.
Prehn sign
Elevation of the painful or swollen testis does not produce relief. Sign for testicular torsion
When do you worry testicular torsion has been picked up late in the game?
Scrotum is swollen. Acutely, there is often no swelling.
When performing the "opening of a book" maneuver to detorse a testicle, how do you know when you have fixed the problem?
Pain relief for the pt. May need to untwist several revolutions
Name 3 populations of patients likely to get renal and ureteral stones.
1. Hyperparathyroidism
2. Men 3rd-5th decade of life
3. Genetic predisposition

Highest frequency during warmest 3 months of the year!
What is the most common composition of renal/ureteral stones?
Calcium oxalate or phosphate
What type of renal stone is associated with infection by urea-splitting bacteria?
Struvite
Name the 2 most common areas of obstruction caused by renal/ureteral stones
1. Uretopelvic junction
2. Uretovesicular junction
The pt with renal stones often presents with N/V, diaphoresis and flank pain that radiates where?
Ipsilateral testicle or labia
Does hematuria have to be present on U/A to diagnose renal/ureteral stones?
No, absent in 10% of cases
What is the preferred imaging for renal/ureteral stones?
CT of abdomen and pelvis
When should you admit the pt with renal/ureteral stones?
Associated infection
Fever
Persistent vomiting
Rule out the common and the deadly. What are the 3 most life threatening gyn emergencies?
1. Ruptured ectopic
2. Ruptured hemorrhagic cyst
3. Ruptured tuboovarian abscess
Name 3 risk factors for spontaneous abortion?
1. Maternal age
2. Paternal age
3. Parity
How much blood is estimated to be lost when a woman says she has soaked a pad with blood?
20-30 mL
Describe the appearance of the cervix with threatened and spontaneous abortion.
Threatened- cervix is closed, with mild bleeding

Spontaneous-cervix is open and passing blood clots, conception products
What is Fitz-Hugh-Curtis Syndrome?
Complication of PID, causing inflammation of Glisson's capsule, a thin layer of CT around the liver. =elevated LFTs

Will see violin string adhesions.
At what level of B-HCG should a fetus be visible within the uterus?
2000-3000

Always repeat levels to see whether there has been a fetal demise, should double q2-3 days
What is the major cause of morbidity and mortality with ectopic pregnancy?
Hemorrhage
This problem is caused by spasm of the adnexal organs or developmental abnormalities of pelvic organs, allowing them to twist
Ovarian torsion
What is the difference between visceral and parietal abdominal pain?
Visceral-dull, poorly localized, often midline. Stimulation of stretch receptors in hollow or solid viscera
Parietal-sharp, well localized pain, irritation of peritoneal fibers
If you are concerned about a SBO, what piece of history is especially important to ask about?
Past surgeries, any possibility of adhesions?
Name 2 common recurrent abdominal pain complaints where the pt will tell you "this feels the same as last time"
Renal colic
Diverticulitis
Name 2 causes of abdominal pain that have nothing to do with GI!
Pneumonia
MI (esp elderly, DM)
Carnett's sign
Have pt do a sit up to determine source of abdominal pain. If relief with ab flexion, pain is intra-abdominal. If pain is increased, is extra-abdominal/peritoneal.
Hover sign
Pt feels pain when you "hover" your hand above the abdomen. Indicates nerve origin rather than abdominal cause
High pitched, tinkling bowel sounds
Bowel obstruction
What does involuntary guarding on physical exam of the abdomen indicate?
Peritoneal irritation
Where will pain from acute cholecystitis refer?
From RUQ to right shoulder
History of gradual onset periumbilical pain (visceral) that progresses to constant RLQ pain (parietal)
Appendicitis
When a pt presents with vomiting as a symptom associated with abd pain, what history is important to elicit about the timing?
Pain before vomiting-appendicitis

Pain after vomiting-Boerhaaves, Mallory-Weiss
Point 1/3 medially from ASIS to umbilicus.
McBurney's point.
tenderness here indicates appendicitis
What will the position and demeanor of the pt be when peritoneal irritation is present?
Pt will prefer to lie still
Name 2 exceptions to the idea that appendicitis should elicit pain over McBurney's point.
1. Pregnancy-appendix displaced, RUQ pain

2. Retro-cecal appendix-pain on rectal examination
Rosving's sign
Pain in RLQ elicited when palpating LLQ.

appendicitis
Obturator sign
RLQ pain with internal/external rotation of right hip

appendicitis
Iliopsoas sign
RLQ pain with hyperextension of the right hip
If you suspect appendicitis, what is your first choice for imaging to confirm?
CT
Even if it's not appendicitis, have 2/3 chance of finding another problem on CT.
What is an appendolith?
Pathognomonic for appendicitis, a fecal ball causing infection
What is the most common diagnosis for ER abdominal pain in the pt >50 yo?
Biliary tract emergency
What does biliary colic indicated?
cystic duct obstruction

post-prandial RUQ pain
radiates to back/shoulder
lasts 30min-several hours
Name 3 risk factors for cholelithiasis
1. Female
2. Obesity
3. Post massive wt loss
4. DM
5. Race: NA>hispanic>white
6. Hemolytic disorders
Cholelithiasis can be difficult to distinguish from dyspepsia, what could you do to separate the two?
Antacid challenge?
What can you do for the pt with suspected cholelithiasis in the ER? They may need to schedule elective surgery for later.
IV hydration
IV analgesia
IV anti-emetics
What happens in cholecystitis?
Obstruction in cystic duct causes inflammation, distension, edema of GB.
Name the 4 typical agents that may cause bacterial infection in cholecystitis.
1. E.coli
2. Klebsiella
3. Enterobacter
4. Enterococci

and anaerobes
Why does acute acalculous cholecystitis have higher morbidity and mortality?
Tend to be sicker, get gangrene and perforation.
Name 3 risk factors for biliary sludging, causing acalculous cholecystitis.
1. DM
2. HIV
3. TPN, prolonged fasting
4. Vascular disease
You'll probably get a spectrum of labs when you suspect cholecystitis. When will LFTs be useful in the diagnosis?
If they are >5x elevated, suspect choledocholithiasis.
Name 3 indications for urgent surgical consultation for cholecystitis.
1. Empyema
2. Emphysematous cholecystitis
3. Perforation
4. Associated pancreatitis or peritonitis
Name 3 risk factors for choledocholithiasis
1. prior biliary injury
2. PSC
3. Cystic biliary disease
4. sphincter of oddi dysfunction (SOD)
5. Asians with parasites
Choledocholithiasis causes obstruction of conjugated bilirubin getting out of the liver. What consequences do you expect systemically?
1. Jaundice- a late finding
2. clay colored stools
3. Dark/tea-colored urine
What diagnostic test could you order for choledocholithiasis that would also be therapeutic?
ERCP with endoscopic sphincterotomy
What is ascending cholangitis?
bacterial infection superimposed on an obstruction of the biliary tree. leads to bacteria reflux into lymphatics and hepatic vessels
-stones
-neoplasm
Charcot's triad
1. RUQ pain
2. fever
3. jaundice

Indicates cholangitis
Reynold's pentad
Charcot's (RUQ pain, jaundice, and fever) plus
4. shock
5. AMS

indicates 100% mortality if cholangitis is not treated.
Name the 2 most common causes of acute pancreatitis
1. Alcoholism
2. Gallstones

blunt trauma, infection, super high hypertriglyceridemia, autoimmune
What patient population is at highest risk for pancreatitis?
Middle aged AAs
What imaging should you order to investigae suspected complications of pancreatitis, remembering pancreatitis itself is a clinical diagnosis?
CT
Name 3 complications of pancreatitis that would warrant getting a CT.
1. Pseudocyst
2. Abscess
3. Hemorrhage
What enzyme to you expect to be most elevated in acute pancreatitis?
Lipase
Who should you call to drain a peri-pancreatic abscess?
Interventional radiology
Name 3 things you can do for the pt with acute pancreatitis in the ER to begin their recovery.
1. NPO
2. IV hydration
3. anti-emetics
4. Analgesics
5. PPIs
6. Observation for EtOH withdrawal
Name 3 hallmarks of SBO
1. Colicky pain
2. Abdominal distension
3. Vomiting of undigested food progressing to vomiting of feculent material
s/p surgery is the most common preceding finding in adult SBO. Name 3 ways children can get SBO.
1. Meckels Diverticulum
2. volvulus
3. Intususception
What is the reasoning behind giving IV fluids to the pt with SBO in the ER?
When obstruction occurs, bowel becomes ischemic. Pump up the vessels with fluid to prevent vascular ischemia.
Name the 2 main causes of PUD
1. H.pylori
2. NSAIDS
Why do we give standard PPIs to postsurgical patients?
Decreased incidence of stress/inflammation associated PUD
Where are most peptic ulcers located?
Duodenum>stomach
What imaging will you order if you suspect perforated PUD?
Abdominal series (plain film) looking for free air. Always order lat decub also.
What imaging should you order to investigate complaints of renal colic?
CT urogram without contrast
When should you consult urology for a renal/ureteral stone?
When it is >5mm
Name 3 risk factors for diverticulitis
1. low fiber diet
2. steroid use/NSAIDs
3. Age >40
Who would you admit for an acute exacerbation of diverticulitis?
1. Peritoneal signs
2. SIRS
3. Complication (perf, abscess)

get IV abx and bowel rest
What abx regimen would be sufficient for an acute exacerbation of diverticulitis?
Metronidazole
or
Cipro
Name 3 risk factors for mesenteric ischemia/infarction
1. Age
2. Hypercoagulable state, prior DVT
3. Afib
4. CHF
5. Atherosclerosis
6. Liver disease
What is the most common location for mesenteric ischemia/infarction?
SMA occlusion by thrombus or embolus
Describe the presentation of the pt with mesenteric ischemia/infarction.
1. Severe, poorly localized abd pain
2. Pain refractory to narcotic analgesics
3. Abd exam is normal
What is ascending cholangitis?
bacterial infection superimposed on an obstruction of the biliary tree. leads to bacteria reflux into lymphatics and hepatic vessels
-stones
-neoplasm
Charcot's triad
1. RUQ pain
2. fever
3. jaundice
Reynold's pentad
Charcot's (RUQ pain, jaundice, and fever) plus
4. shock
5. AMS

indicates 100% mortality if cholangitis is not treated.
Name the 2 most common causes of acute pancreatitis
1. Alcoholism
2. Gallstones

blunt trauma, infection, super high hypertriglyceridemia, autoimmune
What patient population is at highest risk for pancreatitis?
Middle aged AAs
What is ascending cholangitis?
bacterial infection superimposed on an obstruction of the biliary tree. leads to bacteria reflux into lymphatics and hepatic vessels
-stones
-neoplasm
Charcot's triad
1. RUQ pain
2. fever
3. jaundice
Reynold's pentad
Charcot's (RUQ pain, jaundice, and fever) plus
4. shock
5. AMS

indicates 100% mortality if cholangitis is not treated.
Name the 2 most common causes of acute pancreatitis
1. Alcoholism
2. Gallstones

blunt trauma, infection, super high hypertriglyceridemia, autoimmune
What patient population is at highest risk for pancreatitis?
Middle aged AAs
Name 3 risk factors for AAA
1. SMOKING
2. Elderly male
3. Atherosclerosis
4. HTN
5. 1st degree relative with AAA
6. CT/collagen tissue disease
What do you suspect when you find unequal or absent femoral pulses on PE of the pt with abdominal pain? What imaging test will you order?
AAA rupture

Bedside US. Do not send unstable pt to CT
What is the most common cause of upper GI bleed?
Name 3 others
PUD

1. Erosive gastritis/esophagitis
2. Esophageal/gastric varices
3. Mallory-Weiss tears
What is the most common cause of lower GI bleed?
Name 3 others
Diverticular disease

1. AVMs
2. IBD
3. Anorectal disease (hemorrhoids, fistula, fissure)
4. Neoplasia
How can labs help you distinguish upper vs lower GI bleed?
BUN elevated in UGI bleed
List the 4 mechanisms of diarrhea.
1. Increased secretions
2. Decreased absorption
3. Increased osmotic load
4. Increased motility
What time length divides acute and chronic diarrhea?
3 weeks