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8 Cards in this Set
- Front
- Back
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Low endothelial cell density (ECD) is a risk factor for what?
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Cataract and corneal surgeries
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With the ECC machine printout, the Coefficant of variation (CV) is what for a normal endothelium? Active physiological stress to endothelium? Abnormal? What does it represent?
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Normal: 20-30
Stress: 30-40 Abnormal: >40 Level of activity of wound repair. When over active or hyperactive the CV is increased |
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When do you use an ECC?
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Pre-Operative risk assessment (Cat sx or glaucoma filter surgery)
Corneal edema Corneal opacity Corneal dystrophy Iatrogenic endotheliopathy (endothelial problems caused by intraocular sx) CL - related endotheliopathy (CL wear can induce endothelial hypoxia) |
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Why is ECC so important for Pre-op sx?
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Because with sx you generally lose 10-15% of endothelial function. Therefore if you already start with a low number, then you can assess the risk and potential outcome for the pt
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What are some symptoms of endothelial disease?
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Blurred vision
Fluctuating vision Halos around light Photophobia FB sensation CL intolerance |
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What are some signs of endothelial disease?
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Polymegethism, Pleopmorphism, Progressive guttata formation, reduced ECD, increased corneal thickness, loss of trnasparency
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What is the primary goal of tx for endothelial disease? Secondary goal?
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Tx of clinically significant corneal edema
Prevent further damage to the endothelium |
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What are the tx options for endothelial disease?
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Pt education (future sx, CL)
Preventative care Eliminate initiating insult (ie CL endotheliopathy - move them into a higher dk value) 5% sodium chloride solution (or ointment at bedtime) Topical anti-inflammatory Corneal surgery |
