Epithelia And Glands

Front 1

tight junction: zona occludens

Back 1

zone surroudns the entire apical perimeter

formed by fusion of outer leaflets of plasma membrane

have intramembrane strands interlinked to form tight seal

Front 2

intermediate junction: belt desmosome; zona adherins

Back 2

just basal to zona occludens

mat of actin filaments located on cytoplasmic surfaces; attach to E-cadherins (ca dependent for promoting adhesion)

~ fascia adherens (zone of intercalated disks)

Front 3

desmosome

Back 3

small adhesive site

keratin loops in and out of dense plaque

desmoplakin dense plaque of intracellular attachment proteins

Front 4

microvilli

Back 4

composed of 30 actin filmaments through core

Front 5

stereocilia

Back 5

very long microviilli

Front 6

cilia (features)

Back 6

core of microtubules; axoneme (9 +2 conformation) [9 double microtubules around 2 core microtubules]

radial spokes: extend toward central sheath + stabilize cilia

central sheath: sheath that surrounds two central microtubules

nexin: elastic protein that connects adjacent microtubules and helps maintain ciliary shape

Front 7

apocrine secretion

Back 7

secretion in which vesicles are released

Front 8

Immotile cilia syndrome (cause, symptoms)

Back 8

Symptoms: sperm immotility/recurrent respiratory tract infections

Cause: cilia lack dynein arms which prevent proper cilia/flagella movement

Front 9

Carcinomas vs adenocarcinomas

Back 9

both arise from epithelial origins

carcinomas arise from surface epithelium

adenocarcinomas: arise from glandular epithelium

Front 10

Bulbous pemphigoid/Vulgaris pemphigus [Symptoms, Cause]

Back 10

cause: formation of blisters

symptoms: autoimmune disorder: abs produced against hemidesmosomes

Front 11

gap junction

Back 11

communication junction, nexus

connected via connexons (six subunit channels)

Front 12

hemidesmosomes

Back 12

present on basal surface of basal epithelial cells and myoepithelial cells

Front 13

basement membrane

Back 13

composed of basal lamina: lamina lucida (adjacent to basal epithelial cells) and lamina densa

integrins bind to laminins (lamina densa) which bind to enactin/type VII collagen to bind to type IV collagen in reticular layer/lamina densa