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22 Cards in this Set

  • Front
  • Back
Name 4 basic types of tissues
Structural characteristics of epi
-lots of cells tightly linked
-junct. complexes (contacts)
-gap junct.(communication)
-basal cell mitosis
-no bld vessels
Functional characteristics of epi
-transcelluar transport:
*diff of O2 & CO2->lungs
*carrier proteins mediated transport->intestines
*vesicle transport of meds
-selective permeability=tight junct.
Simple cuboidal epi
-same ht./wd.
-spherical nuc in cntr.
-in glands/kidney/ovary
-lines ducts
Simple squamous epi
-nuc in cntr
bld vess,capillaries,bowmans capsule
-in lungs endothelial layer for fluid & gas exchange
Simple columnar epi
-ovid nuc @ base
-secretion,absorption (goblet cells)
-ducts of glands
-lines GI tract
-has microvilli
Pseudo strat. columnar epi
-not all cells on surface
-several layers of nuclei
-crowded cells
-all touch BL
-protective lining,secretory,absorption
-resp tract/epididymus/vas def./trachea/nasal passage
-has stereocillia
Strat. squamous epi
-more than 1 cell layer
-lines mouth,esoph,GI tract
2 types:
Strat. cuboidal epi
-sweat ducts
-2 layers
Strat columnar epi
-salivary glands
Transitional epi
Classes of glands
-endocrine->directly to bld,cell stimulates itself
-paracrine->target cell close by
-exocrine-> have ducts
Exocrine gland classification
(goblet cell/pancreas)
-simple/compound ducts
-tubular/tubulo/alveolar shaped secretion unit
-mucous/serous sec. prod
-mode of sec:
holocrine-whole cell w/ sec is released (sebaceous gland)
apocrine-cytoplasm releases w/ contents (mammory glnd)
Surface specialization of epi
-stereocillia: long microvilli,only in epididymus & cochlea
made of glycocalyx
*brush border=kidney,coats surfaces,has actin filiments in core
*striated border=intestines/ actin filiments
-cillia:ovaduct,have core of microtubules
Junctions that allow for cell comm. & binding
-zona occludens
-zona adherins
-macula adherins
-gap junct.
Zona occludens
-diffusion barrier
-H2O can't pass b/t cells
-keeps memb. proteins from moving to base of cell w/ claudins,laminin,occludens
-binds to microfiliments
-linkers Zo1,Zo2,Zo3 are
affected by cytomegalovirus & cholera:PM becomes permeable
Zona adherens
-below tight junct.
-helps cell w/ mech. & structure
-fuzzy area on inside of PM
-dep on Ca
-bind to E cadheren & actin
-intermediate junct.
Macula adherens
-throughout cell along PM
-made of desoplakin & pakoglobins
-in cadhern family
-Ca dep
Functions of basal lamina
-structure attachment for epi
-interactions w/ other cells
-selective barrier
-movement durig dev
2 zones of BL
zona lucida (rara):
-next to PM
-has laminin
-collagen 4
zona densa:
-next to reticular lamina
-proteoglycan(has extensions of GAGs) ->makes perlacan-> has chains of hep sulfate
-coll 4
Lamina reticularis
-attaches to lamina densa
-made of:
coll 4 anchoring fibrils
fibrillin microfibrils
coll 2 reticular fibers
attachment to base of cell to BL & underlying extracellular matrix