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9 Cards in this Set
- Front
- Back
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Epinephrine Trade Name
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Adrenalin
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Epinephrine Classification
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-natural catecholamine
-sympathomimetic -adrengergic agonist |
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Epinephrine Mechanism Alpha
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-Stimulates alpha, beta 1 and beta 2 receptors
-Alpha agonist:constricts arterioles in skin, mucosa, kidneys, and vicera >>increased sympathetic vascular resistence |
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Epinephrine Mechanism Beta
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-B1 agonist: increases force of contraction(+ inotropic) increases heart rate (+ chronotropic)>>>increased myocardial workload and o2 requirements
-B2 agonist: relaxation of bronchial smooth muscle, dilation of vessels in skeletal muscle; dilation of cerebral, pulmonary, coronary, and hepatic vessles |
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Epinephrine Indications
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-Cardiac Arrest: VF, pulsesless VT, aystole, PEA
-Symptomatic Bradycardia |
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Epinephrine Dosing (Adult)
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Cardiac arrest
-IV/IO: 1mg of 1:10,000 solution, may repeat 1mg q 3-5 minutes -ET 2 to 2.5 times IV dose Symptomatic Brady or hypotension -2 to 10mcg/min |
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Epinephrine Precautions
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-increases myocardial o2 demand
-avoid mixing with sodium bicarbonate |
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Epineprhine Special Considerations
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-should not be given in the same IV line as alkaline solutions-inactivates Epi
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Epinephrine Onset of Action and Duration
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-IV 1-2 minutes
-IV 5 to 10 minutes |
