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40 Cards in this Set
- Front
- Back
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Broad spectrum inducers
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CBZ, phenytoin, phenobarbital
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Selective CYP3A4 Inducers
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Felbamate, topiramate, oxcarbazepine
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Inhibitors
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VPA, Felbamate, topiramate, oxcarbazepine
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Inhibitor of glucuronidation
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VPA
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Glucuronidated drugs
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bzd, morphine, antiretrovirals
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AEDs not affecting oral contraceptives
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vigabatrin, bzd, VPA, Gabapentin, pregabalin, tiagabine, levetiracetam, zonisamide
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Reduce effects of oral contraeptives
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CBZ, phenobarbital, phenytoin, primidone, felbamate, xcarbazepine topiramate >200/day
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Side effects of phenytoin
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Ataxia, purple glove syndrome, gum hypertrophy
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Side effect of carbamazepine
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RASH, tremor, myoclonus, hyponatremia, cardiotoxicity, sexual dysfunction,ophthalmoplegia
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Side effect of valproate
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Tremor, encephalopathy, pedal edema, hypoammonemia, pancreatitis
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Side effects of phenobarbital and primidone
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Connective tissure disorders, erectile dysfunction, sedation
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Side effects of gabapentin and pregabalin
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Myoclonus, pedal edema, weight gain
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Side effects of Lamotrigine
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Dose and titration-dependent rash
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Sde effects of Topiramate
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Renal stones, anomia, paresthesia, weight loss, glaucoma, metabolic acidosis
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Side effects of Zonisamide
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Renal stones, parestesia, weight loss
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Side effects of Tiagabine
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Encephalopathy, tremor, headaches, knee buckling, spike wave stupor
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Side effects of Levetiracetam
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Sedation, mood changes, minor infections, decreased rbc
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Side effects of Oxcarbazepine
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Hyponatremia, diziness
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Side effects of Felbamate
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Aplasatic anemia, hepatic failure
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Side effects of Ethosuximide
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Nausea, vomitting
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Hypothalamic hamartoma
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Gelastic seizures
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Hypsarrhythmia
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Infantile spasms/West syndrome
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3 Hz spike and wave
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Absence
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Slow spike and wave
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Lennox-Gastaut
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Fast spike and wave
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4-5 hz. Primary generalized epilepsies
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Polyspike
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myoclonus
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Spike
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<70msec
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Sharp
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70-200 msec
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PLEDs
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Acute stroke or herpes encephalitis
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Triphasic waves
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Hepatic and renal encephalopathy
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Generalized slowing
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Encephalopathy
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Burst suppression
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Anoxic brain injury, barbiturates, hypothermia
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Cellular correlate underlying surface EEG interictal spike
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Paroxysmal depolarization shift
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Delta
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1-3 hz
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Theta
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4-7 hz
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Alpha
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8-12 hz
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Beta
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13+ hz
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Bilateral independent central-temporal spikes in sleep
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Benign rolandic epilepsy
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Teenager fast spike and wave, vpa helps
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JME
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ACTH
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used to treat infantile spasms
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