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19 Cards in this Set
- Front
- Back
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Broad Spectrum AEDs
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Valproate
lamotrigine topiramate levetiracetam zonisamide primidone |
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Narrow spectrum AEDs
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carbamazepine, oxcarbazepine
phenytonin, tiagabine gabapentine, pregabalin clonazepam |
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Mechanism involves Sodium Channels
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Phenytonin (N)
Carbamazepine (N) Oxycarbamazepine (N) Topiramate (B) Zonisamide (B) Felbamate (B) Lamotrigine (B) Primidone |
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Mechanism involves a Gabatransaminase
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Valproate (N)
Vigabatrin (irreversible inhibitor) |
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Mechanism involves GABA Cl- Channels
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Phenobarbitol
Clonazepam (N) |
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Mechanism Involves vesicles and protein 2A
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Levetiracetam (B)
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Mechanism involves Ca2+ channels
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Pregabalin (N)
Vabapentin (N) |
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Mechanism involves GABA reuptake inhibition
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Tiagabine (N)
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Mechanism involves Potassium Channels
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Ezogabine (remember, its the newest one)
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Mechanism allosteric modulation of GABA receptors
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Lorazepin (N)
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Can be used to treat spinal cord injuries and fibromyalgia.
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Pregabalin (N)
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Best for seizures in infants
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phenobarbitol
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best for secondarily complex, tonic clonic, and partial seizures
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Carbamazepine
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best for absence seizures
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ethosuximide
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causes aplastic anemia
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carbamazepine and felbamate
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teratogenic
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valproate and phenytonin
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causes hepatotoxicity
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valproate and felbamate
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causes sedation
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lorazepam and phenobarbitol
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Makes absence seizures worse
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Carbamazepine
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