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22 Cards in this Set

  • Front
  • Back
Formula for Attack rate
# with risk and disease
___________________
# at risk
What is used in outbreak situations to determine source of agent and disease?
Attack rate for each food served
What are the challenges for determining the source of an outbreak?
Correlated consumption
Cross-contamination
Recall
Quanity
Susceptibility
What is ASSOCIATION?
in Epi, look for association between exposure and disease.
Is association valid?
Is there evidence for causality?
What is meaning of association?
Disease (outcome) is more/less common in people more/less exposed to some "agent"
Important rules of association
If exposure causes an OUTCOME - then always an assn
If an exposure and an outcome are ASSOCIATED, then
- there may be a causal association
- the assn MAY BE DUE TO
*Bias
*Confounding
What are sources of Epidemiologic Data?
*Specifically collected data
- epi studies
*Data collected for gen purposes
- dis surveillance
- hosp/clinic records
- ins records
- employer and school records
- special surveys
- vital records
What are MEASURES of epi
1. (Point) prevalence
2. Cumulative incidence
a. Attack rate
b. Period Prevalence
3. Incidence rate (incidence density)
What is Point Prevalence?
How much disease exists?
N=size of population(at risk)
x= Number of cases in pop.

Prevalence=x/N(x/N*100%)- either % or proportion
example of point prevalence
23.6 mil people - 7.8% have diabetes
What does Cumulative Incidence describe?
How high is the risk?

This is 2. under Measures
Equation for CI
N=size of population at risk
x=Number of NEW cases
T=time period of new cases
T CI=x/N ((x/N*100%)
Use CI to describe a disease situation
The 10 year CI of dental caries was 0.4
CI=Risk
What is 1. under measures
1. Point Prevalencd - how much disease does EXIST
2a. Under Measures describes Attack Rate. Formula?
2.Cumulative Incidence
a. Attack Rate
AR=x/N (x/N x 100%)
During Time period (implicit for plausible incubation period)
Give example of ATTACK RATE
2 out of 144 passengers developed H1N1 influenza
Describe PP (Period Prevalence)
N=size of pop at risk at beginning of F/U
x= number of existing and new cases
T= time period of follow-up
T PP=x/N (x/N x 100%)
Give example of Period Prevalence
30% had the flu during 2008/09 flu season
What does Incidence Rate describe?
How frequently does the disease/outcome develop
What is formula for IR
pt = # of persons at risk during time of observation
x = Number of cases arising from persons at risk during time of observation
IR = x/pt
What do incidence rates measure
Natural measure of frequency( = number of events per population per time)
A rate is normalized so should be independent of number of people or length of time observed.
Example of Incidence Rate
'in 2006, the incidence of diabetes in Texas was 10.2 per 1000 population'