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8 Cards in this Set
- Front
- Back
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Promotor region
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10-35 nucleotides up from the transcription start site
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Holoenzyme
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Combination of sigma facotr and RNA polymerase in ecoli
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Sigma factor
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Binds and recognizes the promoter region
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Histone acetyl transferase
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Adds acetyl onto histone tails, weakening the electrostatic attractions and exposing DNA
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TFIID
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Contains TBP, binds to the TATA box
Positioned near transcription site |
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TFIIA, TFIIB
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Attach once TFIID has bound
Required for RNA polymerase II to bind |
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RNA polymerase II
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Synthesizes DNA in a 5'-3' direction adding nucleotides to the free 3' end
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Other transciption factors required
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TF E,F,H
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