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6 Cards in this Set

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Oxidoreductases

Catalyze oxidation-reduction reactions (transfer of electrons between biological molecules).


-Rxn catalyzed by Oxidoreductases, e- donor known as Reductant and e- acceptor known as Oxidant


-Enzymes with dehydrogenase or reductase are ususally oxidoreductases

Transferases

Catalyze the movement of a functional group from one molecule to another.


-Ex. aminotransferase can convert aspartate and α-ketoglutarate as a pair to glutamate and oxaloacetate by moving the amino group from aspartate to α-ketoglutarate


-Kinases are members of this class, they catalyze the transfer of a phosphate group

Hydrolases

Catalyze the breaking of a compound into 2 molecules using the addition of water.


-Ex. phosphatase cleaves a phosphate group from another molecule.


-Ex. peptidases, nucleases, lipases

Lyases

Catalyze the cleavage of a single molecule into 2 products. Do not require water or act as oxidoreductases.




Catalyze the synthesis of two molecules into a single molecule (when performing this function, known as Synthases)

Isomerases

Catalyze the rearrangement of bonds within a molecule. Can be classified as oxidoreductases, transferases, or lyases depending on mechanism of enzyme.




-Catalyze reactions between stereoisomers and constitutional isomers.

Ligases

Catalyze addition or synthesis reactions, generally between large similar molecules, and often require ATP.


-Synthesis reactions between smaller molecules are generally accomplished with Lyases.


-Likely to be encountered in nucleic acid synthesis and repair.