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5 Cards in this Set
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- Back
- 3rd side (hint)
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Salmonella
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Enteroinvasive.
Gram-negative rod, facultative anaerobe, lactose-negative. Two species: salmonella typhi and salmonella typhimurium Typhoid fever = essentially a disease of the RES Salmonella typhimurium infetion = gastroenteritis Invasion of host cells and survival within macrophage is essential for virulence. Inject effector proteins directly into host cell via Type III secretion. Vaccines for s. typhi are available. |
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Shigella
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Enteroinvasive. Causative agent of bacterial dysentery.
Gram-negative rod, lactose negative. Several species, most virulent = Shigella dysenteriae |
Blood and mucus in stool (indicative of invasive organism causing disease).
Development of HUS may occur. Inbasion confined to lining of colon and ileocecal valve. Shiga toxin: enterotoxic, cytotoxic to several cell lines, inhibits protein synthesis in eukaryotic cells by cleaving 28S rRNA in ribosomes, associated with HUS |
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Camplyobacter jejuni
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Gram-negative curved rods. Grown on enriched medium, microaerophilic conditions.
Major cause of human gastroenteritis world-wide. Contaminated chickens. |
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Yersinia
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Gram negative bacilli
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Acute watery diarrhea, mesenteric lymphadenitis (mimics appendictis)
Mostly affects children. |
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Listeria monocytogenes
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Gram positive coccobacilli (can be confused with GBS)
Grows at 4 degrees Celsius. |
Can have neonatal infetions- may lead to listeria meningitis.
Lysteriolysin O disrupts vacuole membrane within macrophage and allows it to replicate in the cytoplasm. |
