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14 Cards in this Set

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What is acquired angioedema-inflammatory reaction? Etiology/Epidemiology?
reaction of vascular dilation and increased permeability

--Usually from a buildup of bradykinin --

caused by ACE inhibitors, bee stings, transfusions

seen in patients with no specific incidence on history, likely taking hypertension medication
What is the treatment for angioedema - inflammatory reaction?
supply O2
epi
steroids
antihistamines (H1 and H2)

(not necessarily IgE mediated)
What is the Etiology of hereditary angioedema - inflammatory reatction? Pathogenesis? Tx?
Type 1 - AD deficiency of C1 esterase inhibitor
Type 2 - nonfunctional C1 esterase inhibitor

characterized by recurrent mucocutaneous edema around face, mouth and throat

Tx - danazol, treat acute attacks with c1 esterase replacement
20 mo, healthy, woke up fine, but during the day developed fever, SOB, lethargy, difficulty swallowing, and slobbering.
Nostrils flared, scared appearing.

DDx?
Dx?
DDx: Infection:
croup, pneumonia, abscess blocking airway

Asthma
Foreign body
Allergic reaction

Dx: Acute epiglottis
20 mo, healthy, woke up fine, but during the day developed fever, SOB, lethargy, difficulty swallowing, and slobbering.
Nostrils flared, scared appearing.

What to do?
What NOT to do?
Do: Head/neck xray
Take to OR, give anesthesia, Inubate or do scope
Etiology and Presentation of Acute Epiglotitis
used to be almost exclusively H flu
now think Group A hemolytic STEP

usually sudden and rapid, with high fever, drooling, respiratory distress, dysphagia, tripod body position
Management of acute epiglotitis
do NOT manipulate child
xray on parents lap if you have to

This is a medical emergency, so trach if you have to

step 1 - establish airway
step 2 - blood culture
Step 3 - start ceftriaxone, steroids, and do other labs

- keep intubated for few days
How do you differentiate Acute Epiglotits vs. Croup
age - younger in acute epiglotitis toxicity
rapidity - faster in acute epiglotitis
cough - present in Croup
18 mo, choked eating MandM's and drinking soda 6 days ago.
xrays were done, and child was sent home.
however, child is still coughing, and wheezing.

DDx?
Dx?
Epidemiology
foreign body obstruction

do not back-blow or finger sweep

male, toddlers, most common
Offending agents for foreign body obstructions
vegetables
penuts
safety pins
plastics (radiolucent)

Suspicion is key in Dx
Why more common in children?
posterior dentition not developed
incomplete protective swallowing mechanisms

symptoms may disappear, but are likely to return
Importance of location in foreign body obstruction
larynx - hoarsness, stridor (items usually flat, thin)

trachea - audible slap/thud. lots of wheezing

bronchial - expiratory wheeze

(Xrays can be inconclusive... if you suspect - then look!)
23 mo, history of neck swelling and drooling over last 24 hours.
patient has had URI sickness, feverish, stick neck, tilted neck, sore throat for 2 days. anorexia
irritable child, mass in right neck, rotates head to left, cant open mouth, lots of mucus, bulge in the back of the throat.

DDX?
Dx?
retropharyngeal abscess

caused by infection from lymphatic chains run through this space
Epidemiology, complications, pathology, and treatmnet of retropharyngeal abscess
6 months to 6 years
becomes fibrotic and atrophies after the age of 6

can cause airway obstruction, and can ruptures and spread.

mostly G+/anarobes
group A BH Strep
staph aureus
bacteroides

if small, give fluids and AB's, observe
if large - incise and drain w// AB's