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19 Cards in this Set
- Front
- Back
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What creates products synthesized in duct systems?
eg. digestive? |
exocrine glands
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how do exocrine glands secrete hormones?
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into interstial fluid that surrounds sec. cells, diffuses into blood and is then transported to target cells
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hormones affect specific target tissue bc target cells have specific____? that are constantly broken down and sythesized?
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receptors
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receptors decrease due to large amounts of hormone making target cells less sensitive to homones; this is called?
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down regulation
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amount of hormone decreases causing receptors to increase making target cells more sensitive
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up regulation
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hormones that circulate in blood throughout the body are called?
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circulating hormones
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hormones that act locally are called?
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local hormones
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hormone that acts on same cell that secreted it?
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autocrine
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hormone that acts on neighboring cells?
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paracrine hormone
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what hormones bind to receptors INSIDE target cells?
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lipid-soluble hormones
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what hormones bind ON THE PLASMA MEMBRANE, bc they can't diffuse?
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water-soluble hormones
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what chemical class of hormones is attached to TRANSPORT PROTIENS?
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lipid-soluble
eg. steroid, thyroid, nitricoxide |
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what chemical class of hormone ciculates in FREE FORM?
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water-soluble
eg. amine, peptide-protien, ecosanoid |
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response of hormone depends on?
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hormone and target cell
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when W-Soluble cells bind to receptors on the p.membrane it activates ?
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second messenger system;
amplification of original small signal |
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responsiveness of target cells depends on what?
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homone concentration and influence of other hormones,
eg. permissive, synergistic (2 greater than 1), antagonistic (opposses other hormone) |
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how does a L-soluble hormone work?
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hormone diffuses in and alters the gene expression. DNA make mRNA, mRNA directs synthesis of specific protiens on ribosomes, and new protiens alter cell's activity
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what 3 things regulate hormone secretion?
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signals from nervous system
chemical changes other hormones |
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most hormones are regulated by?
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negative feedback system
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