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71 Cards in this Set

  • Front
  • Back

Endocrine glands are ____ organs


-secrete hormones into _____


-have extensive distribution of:

ductless


bloodstream


blood vessels

The endocrine system and the nervoussystem both function to communicate signals

throughout the body to bring abouthomeostasis.

•How does endocrine system compare to thenervous system?


•Both cause ___ in human body


•Endocrine uses ____, Exocrineuses ____


•Endocrine ___ reaction timeExocrine- ___ reaction time

changes


hormones, neurotransmitter


slow, rapid

Ifone system(Endocrine or nervous) goes out of balance your body goes out of:

homeostasis

Endocrine Glands

ductless


secrete into bloodstream


chemicals secreted called hormones


chemicals theymake influence cells far from where they are secreted

Exocrine Glands

haveducts


secrete onto the epithelial surface,


examples of places you can findexocrine glands: sweat glands,mammillary glands, pancreas (exocrine- secretes enzymes into sm intestine) salivary glands

Endocrine glands produce informationalmolecules called

hormones

•Hormones can only affect ____ or____ that have receptors for a specifichormone.

cells (target cells)


organs (target organs)

Cells or organs that do not possessreceptors for a specific hormone:

do not respond to that hormone.

•There are three major classes of hormonesbased on their chemical structure:

1. peptide hormones


2. steroid hormones


3. biogenic amines

1.Mostnumerous in the body


2.Arechains of amino acids




ex. growth hormone

peptide hormones

1.Madefrom lipids (fats)


2.Derivedfrom cholesterol




ex. estrogen

steroid hormones

altered amino acids




ex. thyroid hormone

biogenic amines

Hormone secretion is regulated by a self-adjusting mechanismcalled a

feedback loop

2 types of feedback loops:

negative and positive

Negative Feedback Loop


_____ starts the process like an elevation inblood glucose


the hormone ____ in response to elevate glucose is____


Insulin brings about a ____inblood glucose.

stimulus


secreted, insulin


decrease

Selfregulating loop to control hormones, is ____ in nature

negative

isthe 1st60 seconds of energy you burn before you start burning anything else

glycogen

Type I Diabetes


used to be called:


is a destruction of ____, are destroyed from a ____



juvenile


pancreatic cells that produce insulin, viral infection that causes an autoimmune reaction in the body



Type II Diabetes


_____ based


best thing for it is:


_____ Resistance

lifestyle


diet and exercise and lifestyle changes


insulin

Positive Feedback Loop


-only a _____ in the body


-the stimulusdoesn’t produce an_____ like a negative feedbackloop


-the stimulus _____ the process



few examples


opposite and counteracting effect


accelerates

Ex of positive feedback loop

nursing a child

-The hypothalamusis the link inbetweenthe ____ and is the _____ ofthe endocrine system


-It controls and oversees most _____


-It is located in the inferior region ofthe ____ and just superior to the ______

nervous system and the endocrine system, master gland


endocrine functions


diencephalon, pituitary gland

Thehypothalamus controls most endocrine activity in three ways:


1.Controls release of____ from the _____


2.Secretes _____ from the ____


3.Controls the stimulation and secretion activities ofthe _____

regulatory hormones, anterior pituitary gland


oxytocin (OT) and antidiuretic hormone (ADH), posterior pituitary gland


adrenal medulla



Onlytwo hormones that hypothalamus secretes:

oxytocin and antidiuretic hormone

Thehypothalamus produces regulatory hormones that either_____ pituitary hormone secretion

stimulate or inhibit

•Located just inferior to the hypothalamus

pituitary gland

pituitary gland


--is housed within ________


--connected to the hypothalamus by a thin stalk:


--divided into:

sella turcica of the sphenoid bone


infundibulum


anterior and posterior lobes

Anterior Pituitary


Divided into 3 distinct areas:

1.Pars distalis- larger anterior


2.Pars intermedia- inbetween


3.Pars tuberalis- wraps around tubal area

•Hormones secreted from anterior pituitarygland are ____ byregulatory hormones secretedfrom the ____.


--These regulatory hormones from thehypothalamus to the anterior pituitary travel through a blood vessel network called the _____

regulated


hypothalamus


hypothalamo-hypophyseal portal system

Anteriorpituitary ____ it


Posteriorpituitary ____ it

makes


stores

Regulatinghormones are hormones that:


Inhibitinghormone are regulating hormones that:

causeother things to do stuff


shut down other stuff

Regulatinghormones travel through bloodstream and blood brings them:

toant pituitary and they diffuse through ant pit walls –is slow

There are seven major hormones secreted from the anteriorpituitary:

TSH, PRL, ACTH, GH, LH, FSH, MSH

Increased in pregnancy and during timesof stress and times of low temperature exposure

TSH

Released during pregnancy to regulatemammillary growth and involved in breast milk production

PRL

1.Stimulates the adrenals, specificallythey adrenal cortex

ACTH

Stimulates cell growth and division andalso stimulates the liver to make hormones for long bone growth

GH

Present in male and female, influencereproductive system and gamete production and maturation

LH and FSH

From melanin synthesis which ceases priorto adulthood

MSH

Posterior Pituitary




-derived from:


-Comprised of the following regions:


-Neural connection between the hypothalamus and the posteriorpituitary is the:

embryonic diencephalon


–pars nervosa–infundibular stalk


•hypothalamo-hypophyseal tract

2 hormones that posterior pituitary stores and releases:

oxytocinand antidiuretic

stimulatescontraction of the uterus walls for child birth and stimulates milk ejectionfor breast feeding (in women)—in men: it causes smooth muscles contraction torelease semen during sexual activity

oxytocin

resultsin water retention in body and plays a part in vasoconstriction of bloodvessels

ADH

•The largest gland entirelydevoted to endocrine activities

thyroid gland

Thyroid Gland


•Located just inferior to the _____ and anterior to the ____


•Butterfly shape with _____ connectedby a midline ____



thyroid cartilage, trachea


right and left lobes, isthmus

•Functional unit of the thyroid gland

thyroid follicle

Thyroid Follicle

•Comprised of simple cuboidal cells thatproduce an iodinated glycoprotein called____ that is stored internally as acolloid


thyroglobulin (TGB)

The follicle cells and the internalstorage area for TGB is collectively called the _____

•thyroid follicle

Large endocrine cells located betweenthyroid follicles called:

•parafollicular cells

•parafollicular cells secrete ____ which helps to ____

calcitonin, regulate serum calcium

Smallglands (usuallyfour) embeddedon theposterior surfaceof the thyroidgland

parathyroid glands

Thereare two types of cells that are seen in the parathyroid gland:

chief cells and oxyphil cells

1.secreteparathyroid hormone (PTH) thathelps regulate serum calcium

chief cells

Paired glands anchored on the superiorborder of the two kidneys; also called:

•suprarenal glands

•Divided functionally into an outer _____ andan inner _____

adrenal cortex


adrenal medulla

Adrenal Cortex


Threedistinct layers of cells (from superficial to deep):

Zona glomerulosa


Zona fasciculata


Zona reticularis

producemineralocorticoids,the main one being aldosterone

Zona glomerulosa

produceglucocorticoids, the main one being corticosterone

Zona fasciculata

produce the sex hormones, estrogen- andtestosterone-related hormones

Zona reticularis

•Formsthe inner core of the adrenal gland

Adrenal Medulla

Adrenal Medulla


•Consistsof _____, which are modified cells of thesympathetic division of the autonomic nervous system


--Secretes:

chromaffin cells


norepinephrine and epinephrine

•Both an exocrine (ducted gland) and endocrine (ductless)gland

Pancreas

•About 98–99% of pancreatic cells are _____ that produce alkaline pancreatic secretions into ducts


•The remaining 1–2% of cells are smallclusters of endocrine cells called _____ (islets of Langerhans)


--The hormones of the islet cells closelyregulate the level of _____

pancreatic acini


pancreatic islets


blood glucose

Pancreatic Islets


Comprisedof four different types of endocrine cells, each secreting a different hormone:

alpha cells, beta cells, delta cells and F cells

secrete glucagon


secrete insulin


secrete somatostatin


secrete pancreatic polypeptide

Alpha cells


beta cells


delta cells


F cells

•Secretes melatonin, which is involved in maintainingthe 24-hour circadian cycle and sexual maturation

pineal gland

•Located just superior to the heart andjust deep to the sternum

thymus

•It is located in the posterior region ofthe epithalamus

pineal gland

•Larger in infants and children than inadults

thymus

•Functions in association with thelymphatic system to regulate and maintain body immunity•

thymus