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34 Cards in this Set

  • Front
  • Back

functions of the endocrine system

1. reproductive functions control


2. growth and development


3. electrolyte, water and nutrient balance


4. cellular metabolism and energy balance


5. mobilization of body defenses

exocrine glands

1. nonhormonal substances like sweat and saliva


2. have ducts to carry secretion to membrane surface

endocrine glands

produce hormone and lack ducts

ductless glands

1. release hormones into tissues


2. high BV and lymphatic drainage

Endocrine only glands

pituitary, thyroid, parathyroid, adrenal, pineal

neuroendocrine glands

hypothalamus

glands in the brain

pineal, hypothalamus, pituitary

neck and chest glands

para and thyroid

abdominal glands

pancreas and adrenal

what are hormones?

1. intracellular chemical signals


2. secreted into interstitial fluid


3. carried by blood to all body parts


4. receptors

hormone-receptor interaction depends on...

1. hormones in blood


2. number of receptors


3. affinity for binding

receptors dynamic

up and down regulation

how are hormones controlled

blood levels and negative feedback loops

humoral stimuli

changing blood levels of ions and nutrients directly stimulate secretion of hormones

neural stimulu

nerve fibers stimulate hormone release

amino acid based hormones

for therapy, must be injected

steroid

made from cholesterol

eicosanoids

not true hormones

hormonal stimuli

1. hypothalamic hormones stimulate release of most anterior pituitary hormones


2. anterior pituitary hormones stimulate targets to secrete still more hormones


3. hypothalamic-pituitary-target endocrine organ feedback loop

hormones in the blood

circulate either free or bound; steroids and thyroid hormones are only bound ones

concentration of circulating hormone reflects

rate of release and speed of inactivation and removal from body

permissiveness

hormone effect requires the action of another

synerginism

amplification of effect

antagonism

hormones have opposite effects

hypothalamus

master of endocrine system

FSH

acts on gonads of both sexes

TSH

acts on release of T3 and T4

Lutenizing hormone

promotes sperm and ovary

oxytoxin

uterine contractions

thyroxine

metabolic rate

parathyroid

acts on bone and kidney

Cushing's disease

hypersecretion

Addison's disease

hyposecretion

diabetes mellitus

high blood glucose levels