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15 Cards in this Set

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MCC death in acromegaly
cardiac failure
elevated HVA
Adrenal neuroblastoma in kids
two hormones that are diabetogenic?
GH and Cortisol
Describe autoimmunity of Graves
Type II hypersensitivity
IgG antibody that stimulates the TSH receptor
what contributes to pretibial myexedema and exopthalmos in Graves?
glycosaminoglycan buildup since fibroblasts behind orbit and in shin express TSH receptor
hyperplasia of follicles with scalloping of the colloid
Graves
germinal centers and Hurthle cells
Hashimotos
Hashimotos HLA and risks?
HLA DR5 and non-Hodgkin's B-cell lymphoma
very tender, painless thyroid
Subacute DeQuervain's thyroiditis (after a flu like illness)
fixed hard as wood non tender painless thyroid
Riedel's fibrosing thyroiditis

What does it mimic?
anaplastic carcinoma but patients are younger and there are no malignant cells
risk of what due to childhood radiation
Papillary carcinoma of the thyroid

what do you see?
orphan annie nuclei and psammoma bodies and nuclear grooves (great prognosis)
RAS mutation in what thyroid cancer?
Follicular carcinoma
What carcinomas spread hematogenously?
choriocarcinoma, Renal cell carcinoma, follicular carcinoma, hepatocellular carcinoma
sheets of cells in amyloid stroma
medullary carcinoma

what does it produce?
what is it associated with?
oncogene?
Calcitonin
MEN 2a and 2b
RET mutation
resorption of bone leading to fibrosis and cystic spaces
osteitis fibrosis cystica

which dz?
primary hyperparathyroidism