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26 Cards in this Set

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what is the function of calcium?
muscle contraction
electrical conduction along nerves
MCC of hyperparathyroidism?
benign adenoma of the gland
what is an enlargement of all four parathyroid glands called?
parathyroid hyperplasia
a patient with brittle bones and a shortened QT interval, what do you suspect?
hyperparathyroid
name two causes of > calcium levels
HPT
Lymphoma
how do you Dx parathyroid problems?
PTH levels
Ultrasound
EKG
what is Addison's disease?
A gradual destruction of the adrenal gland; 70% of the cases are autoimmune
what lab results would you expect with Addison's disease
< cortisol
< aldosterone
what is Schmidt's syndrome?
A type II polyendocrine deficiency; usually affect young adults and can include a hypoactive thyroid, slow sexual development, diabetes, and vitiligo
Name some causes of Addison's disease
Autoimmune
TB
Granulomatous disease
Metastases
Withdrawal of steroids
30 minutes after an injection of ACTH, you measure the blood and urine cortisol levels. You observe no change, what do you suspect?
adrenal insufficiency (addison's)
What is Conn's disease?
primary hyperaldosteronism
what causes Conn's disease?
Benign adenoma
Adrenal hyperplasia
what may be the only symptom of Conn's disease?
HTN
how do you treat Addison's?
Hydrocortison for life
what electrolyte lab results would you expect with Conn's disease?
> in Na
< in K
what test should you do if you suspect Conn's?
Measure blood aldosterone and renin levels

In Conn's:
Aldosterone is high
Renin in low
how do you treat adrenal adenoma?
removal
how do you treat adrenal hyperplasia?
Spirinalactone (aldosterone antagonist)
what is Cushing's syndrome
excess production of cortisol by the adrenal glands.
your patient has > serum cortisol and > ACTH, what do you suspect?
Cushing's disease
how do you Dx Cushing's?
Do a 24 hr free cortisol level test

If >100ug, test is positive
paroxysmal attacks of headaches, sweating, palpitations, high B/P
Pheo
thyroid cancer accompanied by recurring cancer of the adrenal glands
MEN II

Hereditary-get fam hx
mucosal neuromas
puffy lips
prominent jaw
MEN IIb
what meds are given after removal of the thyroid?
Synthroid low dose
calcium supplements