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24 Cards in this Set
- Front
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Somatrem (Protropin) |
Growth hormone (GH) replacement to treat dwarfism. has identical amino acid sequence of pituitary GH plus an additional amino acid
s/e develops antibodies to itself, hyperglycemia
Give IM or subQ
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Somatropin (Humatrope, Nutropin) |
Growth hormone (GH) promotes bone growth at epiphyseal plates, for dwarfism, AIDs wasting syndrome Medicine may be reconstituted and lasts for < 1wk in refrigerator If not reconstituted, refrigerate <1month Give subQ or IM only dont use if cloudy s/e hyperglycemia, pancreatitis, antibodies to growth hormone
cannot use in pediatric clients whose growth deficiency is b/c of Prader-Will syndrome, are severely obese, or have severe respiratory impairment because death has occurred.
effects child if pregnant |
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Bromocritpine (Parlodel) |
Growth hormone Suppressant Drug for acromegaly. may be used with pituitary radiation or surgery to decrease GH levels. Will decrease lactation and prolactinoma give PO
s/s headache, depression, anxiety, seizures, hallucinations, orthotstatic hypotension, shock, dysrythmia, bradycardia, blurred vision, n/v anorexia, constipation, diarrhea, urinary frequency or retention, or incontinence, rash on face arms effects child if pregnant
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Octreotide acetate (Sandostatin) |
Growth hormone Suppressant Drug for acromegaly, or to treat severe diarrhea associated with metastatic carcinoid and other tumors
can be used alone or with surgery or radiation
give SubQ
effects both mother and child if pregnant
s/s headache, dizziness, weakness, seizure, sinus bradycardia, dysrythmias, CHF, HTN, QT prolongation, ST orT wave changes, hypo/hyper glycemia, hepatitis, GI bleeding, pancreatitis |
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Adrenocorticotropic hormone (ACTH) |
Adrenal stimulating pituitary hormone to secrete cortisol. Is corticotropin. OBTAIN plasma cortisol level before and 30 min after giving Can be used to diagnose adrenal gland disorders, treat adrenal gland insufficiency, and as inflammatory. Used to treat acute Multiple Sclerosis
Interacts with diuretics and anti Pseudomonas penicillins and result is HYPO kalemia. This med with digitalis and Hypokalemia can result in digitalis toxicity Phenytoin, rifampin and barbiturate decrease its effects if diabetic need more insulin
s/e n/v increased appetite, mood swing (euphoria to depression) petechiae, water and sodium retention, hypokalemia, hypocalcemia
interacts with asprin and NSAIDS= hypoprotrombinemia; with thiazide and loop diuretics may increase potassium loss
adverse rxn- edema, ecchymosis, osteoporosis, muscle atrophy, growth retardation, decreased wound healing, cataracts, glaucoma, menstrual irregularities
life threatening- ulcer perforation, pancreatitis
affects child if pregnant |
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Desmopressin acetate (DDAVP) |
Antidiuretic hormone (ADH) promote water reabsorption for diabetes insipidus, hemophilia A, and von Willebrand disease
Can have long duration of action 5 -21 hours
s/s drowsiness, lethargy, seizures d/t hyponatremia, anaphylaxis IV effects both mother and child if pregnant |
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Vasopressin (Pitressin) |
Antidiuretic hormone (ADH) promotes water reabsorption from renal tublues for diabetes insipidus, for relief of intestinal distention. Decreases GI bleeding from esophageal varices. Can be given intranasally.
s/e drowsiness, headache, increased b/p, cardiac arrest, shock, MI, rhinitis, n/v, uterine cramping, tremor
Duration of action is 2-8hours
effects child if pregnant |
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Levothyroxine (Synthroid, Levothroid) |
T4 Thyroid Hormone Replacement to treat hypothyroidism, simple goiter, and chronic lymphocytic (Hashimoto) thyroiditis, myxedema, and cretenism
s/e n/v, diarrhea, cramps, tremors, nervousness, insomnia, headache, weight loss
adverse rxn-tachycardia, HTN, palpitations
drug interaction-may increase cardiac insufficiency with epinephrine, increase effects of anticoagulants, tricyclic antidepressants, vasosupperssors, decongestants, decrease effects of antidiabetics, digitalis, has decreased absortpion with cholestyramine or colestipol
effects preganant mother |
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Liothyronine (Cytomel) |
is T3 Thyroid Hormone Replacement. has a short half life and duration of action and so is not recommended for maintenance therapy. Is used as initial therapy for myxedema and is better absorbed by GI tract and so is faster acting.
effects mother if pregnant
decreases effects of digitalis, insulin and oral diabetic drugs.
s/s cardiac
Estrogen increases the effects of this drug |
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Methimazole (Tapazole) |
Antithyroid drug for hyPERthyroidism. Inhibits thyroid hormone synthesis. Takes one week for effect. S/s rash, urticaria, headache, and GI upset may occur. useful for treating thyrotoxic crisis and in preparation of subtotal thyroidectomy. Is 10 times more potent that PTU drug (below)
may cause goiter, decrease effect of insulin and oral diabetics, digoxin and lithium increase the action of it, phenytoin (dilantin) increases serum T3 level, can cause increase in anticoagulation if used with anticoagulant such as warfarin (coumadin) |
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Propylthiouracil (PTU) |
Antithyroid drug for HYPERthyroidism, Graves disease, inhibits T3 and T4 conversion. May be used after surgery or radioactive iodine treatment, palliative control of toxic goiter.
s/s may cause severe liver damage, liver failure, and death may cause goiter, decrease effect of insulin and oral diabetics, digoxin and lithium increase the action of it, phenytoin (dilantin) increases serum T3 level, can cause increase in anticoagulation if used with anticoagulant such as warfarin (coumadin) |
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Strong iodine solutions (Lugol's solution, potassium iodide solution)
potassium iodide (SSKI) |
Antithyroid drug that can supress thyroid function for pt who has undergone subtotal thyroidectomy d/t Graves disease.
will reduce size and vascularity of thyroid gland. dilute drug and administer AFTER meals, sip through straw to avoid discoloration of teeth. Maximum effect after 10 to 15 days |
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Caltcitrol (Rocalcitrol) |
Vitamin D analog for hypocalcemia associated with hypoparathyrodism and for pseudohypoparathyroidism can manage hypocalcemia in chronic renal failure
s/s anorexia, n/v, diarrhea, cramps, drowsiness, headache, dizziness, lethargy, photophobia, can get tetany (hypocalcemia)
drug interaction- increase cardiac dysrythmias with digoxin, verapamil; decrease calcitrol absorption with cholestyramin
increases serum calcium with thiazide diuretics, calcium supplements adverse reactions- hypercalciuria, hyperphosphatemia, hematuria
monitor serum calcium levels weekly during early therapy
effects child in pregnancy |
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Calcitonin (Calcimar (salmon) and Cibacalcin(human)) |
Decreases serum calcium in hypERcalcemia, HyPERparathyroidism, Padgets disease (osteitis deformans). Calcitonin decreases serum calcium by binding at receptor sites on osteoclast. s/e headache, tetany, chills, fever, nasal congestion, N/V, diarrhea, diuresis, nocturia, rash, tingling of hands, dyspnea, anaphylaxis affects child in pregnancy |
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Etidronate (Didronel) |
decreases calcium in hypercalcemia caused by antineoplastic therapy, for Pagets disease
affects child in pregnancy |
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Calcium gluconate |
Electrolyte replacement- calcium product
DO NOT give IM
s/e shortened QT, heart block, dystrhythmias, cardiac arrest IV, hypercalcemia, coma, N/V, anorexia, polyuria, pain at IV site, severe venous thrombosis |
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Calcium chloride |
Electrolyte replacement, calcium product
same as calcium gluconate
DO NOT give IM
s/e shortened QT, heart block, dystrhythmias, cardiac arrest IV, hypercalcemia, coma, N/V, anorexia, polyuria, pain at IV site, severe venous thrombosis |
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Prednisone |
Glucocorticoid to decrease inflammatory occurences, as an immunosuppressant, to treat dermatologic disorders
caution if have fungal infection, diabetes
s/e nausea, diarrhea, abdominal distention, increased appetite, sweating ,headache, depression, flush, mood change
drug interaction- increase effect with estrogens, diltiazem, ketoconazole; decreased effect with barbiturates phenytoiin, rifampin. Use with asprin and NSAIS increase GI toxicity. Use with diuretics and amphotericin B increase potassium depletion, se with cardiac glycosides increase risk of dysrythmias, and digitalis toxicity |
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Hydrocortisone |
SHORT ACTING Glucocorticoid for adrenocortical insufficiency and inflammation. Acetate form can be injected into joints
s/e burning, folliculitis, pruritus, dermatitis, maceratio, hyperglycemia, glucosuria
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Methylprednisolone (Solu-Medrol) |
INTERMEDIATE ACTING Glucocorticoid for inflammatory conditions such as arthritis, bronchial asthma, allergic reactions and cerebral edema
s/e depression, sweating, headache, mood change, circulatory collapse, thrombophlebitis, embolism, HTN, fungal infection, intraocular pressure, diarrhea, nausea, GI hemorrhage, thrombocytopenia, acne, poor wound healing, petetchia, fractures, osteoporosis |
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Dexamethasone (Decadron) |
LONG ACTING Glucocorticoid. Potent antiinflammatory drug. For acute allergic disorders, asthma attack, cerebral edema and unresponsive shock. For diagnosis of Cushings syndrome and depression. Give with food if oral dose
used for ophthalmic disorders
s/e burning, stinging, poor vision, corneal ulcerations, increased Intraocular pressure, optic nerve damage |
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Fludrocortisone acetate (Florinef acetate) |
Mineralocorticoid. for adrenocortical insufficiency, Addisons disease, or salt losing andreno genital sundrome. Used only for its mineral corticoid effects.
s/e flushing, sweating, headache, paralysis, dizziness, seizures, HTN, circulatory collapse, thrmobophlebitis, embolism, CHF, edema, tachycardia, weight gain, hyperglycemia, hypokalemia, cataracts, GI ulcers, anaphylaxis, fractures, osteoporosis, weakness |
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Glucocorticoid client teaching |
TAKE with food b/c glucocorticoids irritate gastric mucosa and cause peptic ulcer
EAT foods rich in postassium (fresh and dried fruit, veg, meat and nuts) as these drugs promote K loss.
take as prescribed, dont abruptly stop (dose is tapered) dont take during pregnancy as harms fetus certain herbal laxatives and diuretics may interact and may increase severity of hypokalemia
watch for respiratory infection b/c these drugs suppress immune system
be careful if have surgery and carry a MedicAlert card stating this is taken
teach client to use nebulizer and avoid overuse or rebound effect occurs
teach overdose s/s of Cushings syndrome (moon face, puffy eyelids, edema in feet, increased bruising, dizzines, bleeding, menstrual irregularity
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Mineral corticoids |
secret aldosterone which is controlled by renin angiotensis system. Maintain fluid balance by promoting reabsorption of sodium from renal tubules
Monitor serum potassium and for hypokalemia |
