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31 Cards in this Set

  • Front
  • Back
Thyrotropin-releasing hormone
(TRH)
Hypothalamus
Peptide
Phospholipase C (IP3/Ca++)
Stim secretion of TSH & Prolactin
Corticotropin-releasing hormone
(CRH)
Hypothalamus
Peptide
Adenylyl Cyclase (cAMP)
Stim Secretion of ACTH
Gonadotropin-releasing hormone
(GnRH)
Hypothalamus
Peptide
Phospholipase C (IP3/Ca++)
Stim secretion LH & FSH
Somatostatin or Somatotropin release-inhibiting hormone
(SRIF)
Hypothalamus
Peptide
Inhibits secretion of GH
Dopamine or Prolactin-inhibiting factor
(PIF)
Amine
Hypothalamus
Inhibits secretion of prolactin
Growth-hormone-releasing hormone
(GHRH)
Peptide
Phospholipase C (IP3/Ca++)
Hypothalamus
Stim secretion of GH
Thyroid-Stimulating Hormone
(TSH)
Peptide
Ant. Pit.
Adenylyl Cyclase (cAMP)
Stim synthesis & secretion of thyroid hormones
Follicle-stimulating hormone
(FSH)
Peptide
Ant. Pit.
Adenylyl Cyclase (cAMP)
1. Stimulates sperme maturation in the sertoli cells of the testes
2. Stimulates follicular development & estrogen synth in ovaries
Luteninizing hormone
(LH)
Peptide
Ant. Pit.
Adenylyl Cyclase (cAMP)
1. Stimulates testosterone synth in the leydig cells of the testes
2. Stimulates ovulation, formation of the corpus luteum, estrogen & progesterone synth in the ovaries
Growth Hormone
(HGH)
Peptide
Ant. Pit.
Stim protein synth &overal growth
Prolactin
peptide
Ant. Pit.
Stimulates milk production & secretion in breast
Adrenocorticotropic homone
(ACTH)
Peptide
Ant. Pit.
Adenylyl Cyclase (cAMP)
Stim synth & secretion of adrenal cortical hormones (cortisol, androgens, & aldosterone)
Melanocyte-stimulating hormone
(MSH)
Peptide
Adenylyl Cyclase (cAMP)
Ant. Pit.
Stimulates melanin synthesis (? humans)
Oxytocin
Peptide
Post. Pit.
Phospholipase C (IP3/Ca++)
Stim milk ejection from the breasts & uterine contractions
Vasopressin or Antidiuretic hormone
(ADH)
Peptide
Post. Pit.
V1 Receptor: Phospholipase C (IP3/Ca++)
V2 Receptor: Adenylyl Cyclase (cAMP)
Stimulates H2O absorption in principal cells of collecting ducts & constriction of arterioles
Triiodothyronine (T3) & L-thyroxine (T4)
Amine
Thyroid
Stimulates skeletal grouth; oxygen consumption; heat production; protein, fat, and carbohydrate utilization; perinatal maturation of the CNS
Calcitonin
Peptide
Adenylyl Cyclase (cAMP)
Thyroid
Decreases serum Ca++
Parathyroid hormone
(PTH)
parathyroid
peptide
Adenylyl Cyclase (cAMP)
increases serum Ca++
Cortisol (glucocorticoid)
Steroid
Adrenal Cortex
Stim gluconeogenesis; inhibits inflammatory response; suppresses immune response; enhances vascular responsiveness to catecholamines
Aldosterone (mineralcorticoid)
Steroid
Adrenal Cortex
Increases renal NA reabsorption, K secretion, and H secretion
Dehydroepiandrosterone (DHEA) & Androstenedione (adrenal androgens)
Steroid
Adrenal Cortex
Stimulates spermatogenesis; stimulates male secondary sen characteristics
Testosterone
Steroid
Testes
Stimulates spermatogenesis; stimulates male secondary sen characteristics
Estradiol
Steroid
Ovaries (lesser degree corpus luteum)
Stim growth & development of female reproductive system, follicular phase of menstrual cycle, development of breasts, prolactin secretion, maintains pregnancy
Progesterone
Steroid
Ovaries (lesser degree corpus luteum)
Stim luteal phase of menstrual cycle, maintains pregnancy
Human Chorionic gonadotropin
(HCG)
Peptide
Adenylyl Cyclase (cAMP)
Placenta
stim estrogen & progesterone synth in corpus luteum of early pregnancy
Human placental lactogen (HPL) or Human chorionic somatomammotropin
Peptide
has GH-like and prolactin-like actions during pregnancy
Insulin
peptide
Tyrosine Kinase Mech.
pancreas
Beta cells
decreases blood [glucose]
Glucagon
peptide
Adenylyl Cyclase (cAMP)
pancreas
alpha cells
increases blood [glucose]
Renin
Kidney
Peptide
catalyzes conversion of angiotensinogen to ang I
1, 25- Dihydroxycholecalciferol
Steroid
Kidney
Increases intestinal adbsorption of Ca++, Bone mineralization
Norepinephrine, epiepherine
amine
adrenal medulla
actions of the sympathetic nervous system.