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25 Cards in this Set

  • Front
  • Back

3 classes of chemical structure

Amino acid derivitate- thyroid hormones catecholamines


Peptide- pancreas insulin and glucogon oxytocin


Steriods- cholesterol androgen cortisol

Epinephrine action

Primary action- muscle glycogen - lactate


Secondary action- liver glycogen to glucose

Function of epinephrine

Activate adenyl c yclase in the presence of Mg to hydrolyse ATP to cAMP


Hydrolysis triglycerides to form FFA

Function of cAMP

Convert inactive protein kinase to active protein kinase

Function of ATP

Convert inactive phosphorylase kinase in the presence of Ca to phosphorylase kinase

Phosphorylase a

Formed from phosphorylase b


Covert glycogen to glucose

Glucogon

Acts only on the liver


Proglucogon until amino acids are removed

Progesterone

Produce by the corpus luteum and the placenta

Function of progesterone

Implementation of the zygote


Inhibit uterine contraction


Allow pregnancy to go to full term


Prevents spontaneous abortion


Stimulate the growth of breast and uterus


Increase body temperature

Estrogen

Estrone estradiol estriol


Ovary- E1 and E2


Placenta- E1 E2 E3 in second a third trimester

Function of estrogen

Influence t he proper development maintenance and functions of reproductive organs


sexual activity cycle


Secondary sec characteristics

Estrogen on cardiovascular system

Increase HDL


increase platelet aggregation


Decrease clotting time


Help in the menstrual cycle yo prevent haemorrhage

Estrogen effects on metabolism

Lipogenesis


Allows for the distribution of fat across the body for shape and form


Increase in HDL


Increase blood triglycerides


Increase protein synthesis

Effects of estrogen on reproductive system

Maintenance of the menstrual cycle


Promote growth of breast uterus overy and vagina


Synthesis of progestron rceptors

Androgen

Testosterone


Produce by laying cells and adrenal cortex

Active metabolite of androgen

5 alpha dihydotestosteron

Function of androngen

Imfluence the proper development maintenance and function of reproductive system and secondary sex characteristics

Androgen effects on specific tissue

Sperm formation and delevery


Enlargement and thickening of the vocal cords


Hair distribution


Increase muscle and bone mass due to its ability to retain nitrogen from protein bone maturation


Male behavior


Cessation of growth

Cortisol as an anti-inflammatory

Interferes with normal cellular processes


Wound healing


Inflammation


Growth

Use of cortisol in surgery

Suppression of immune system for organ transport


Allergies and asthma


Increase resistance

Aldosterone

Acts on DCT


increase Na


Decrease H and K

Cortisol

Catholic actions


Increase amino acids

A chain on the insulin

21 aa


Interchain disulphide ridge


Two mechanisms that protect insulin

Down regulation


Negative corperactivity- once insulin bind the other receptors will have a lessor affinity for insulin

Fasting blood glucose level

6.7 mmol/l


120mg/dl