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71 Cards in this Set

  • Front
  • Back
where does the embryology of they thyroid gland begin??
As an epithelial proliferation at the juncture between the anterior 2/3 and posterior 1/3 of the tongue… later the forame cecum
What is the the theyroglossal duct
canal that connects thyroid to tongue during thryroid migration
where is a thryroglossal cyst found
at any point along the migratory path of the thryroid gland… always near or in the midline of th eneck. 50% are close to or inferior to the body of the hyoid bone
what is the ultimobranchial body?
a remnant of the 5th pharyngeal pouch that gives rise to the parafollicular or C cells of the thryorid gland that secretee calcitonin
what does the isthmus cover
2nd 3rd and 4th tracheal rings
Where do the lateral lobes of the thryoid exted to?
attachments of the sternothyroid muscles
What do the sternothyroid muscles prevent
the upward pathologic enlargment of the theyroid gland.
what can enlargements of the medial portion of the thyroid gland affect?
trachea, esophagus and recurrent and external laryngeal nerves
what are the main blood suplliers to the theyroid
superior and inferior, sometimes thyroid ima
what is the thyroid ima abranch of
usually brachio cephalic trunk
where to the superior and middle thyroid veins drain to?
internal jugular
where does the inferior theyroid vein drain to?
brachiocephalic
where does the lymphatic drainage of the thyroid gland go
ultimately deep cervical lymph nodes
how is autonomic nerve supply provided to the thyroid gland?
via direct branches from the sympathetic chain
Where do the parathyroid glands arise from
Epithelium of the third pharyngeal pouch yeild inferior parathyroid glands and the thymus the fourth pharngeal pough forms the superior parathyroid glands
what is the arterial, venous and lymphatic supply of the thrymus
Inferior thyroid arteries and internal thoracic arteries; inferior theyroid and brachiocephalic veins; and tracheobronchial and superior mediastinal nodes
Specific location of the superior parathryoids
Posterior surface of the thrydoid gland, anterior to the false capsule of the thyroid
Specific location of the inferior parathryoids
Posterior surface of the thrydoid gland, posterior to the false capsule of the thyroid
how can parathyroid tumors be found in the thorax?
The primordia of the thymus gland does not release the inferior parathryoid.
what is the venous, lymphatic and autonomic nerve supply of the parathyroid
same as the thyroid
Which parathyroids are more easily injured durin ga thyroidectomy
The superior b/c they're anterior to the "false capsule" and the left b/c they lie closer to the tracheo-esophogeal groove
What forms the pancreas
the dorsal and ventral pancreatic buds originating from the endodermal lining of the duodenum
When the duodenum rotates to the right where does the ventral pancreatic bud move?
dorsally
What forms the uncinate process
ventral bud (also the head) rest of the pancreas is dorsal bud
When are islets of langerhans developed?
3rd month of fetal life
where are the islets of langerhand sfound?
throughout the pancreasst but majority in tail and adjacent body
What does the head of the pancreas lie on?
inferior vena cava and renal veins
Pt. with painlesss jaundice
may have a tumor in the head of the pancreas blocking the common bile duct
What is posterior to the neck of the pancreas?
portal vein- tumor may obstruct
what does the body of the pancreas lie across
aorta, inferior vena cava and the left renal vein and recheas the left kidney and supra renal gland
pt. with bachache
lesion of the body of pancrease… peptic ulcer epigastric pain now goes to back
arterial supply of pancrease
anterior and posterior arterial arcades from gastroduodenal and superior mesenteric vessels. Also spelic and left gastroepiploic
Venous drainage of pancrease
splenic vein and its tributaries
Lymphaitc drainage of pancreas
nodes adjacent to head, neck, body and tail
Where is the suprarenal gnald derived from?
outer mesoderm, inner medulla ectoderm of nerual crest
at birth the suprarenal gland
is bigger than the kidney; the primitive or fetal cortex makes up the bulk of the gland; but by 2nd week has lost 1/3 of weight due to losss of primitive cortex
Zones of permanent cortex
zona glomerulosa, sona fasciculata and zona reticularis, not complete until a baby is 3 years old
Why is the cortex yellow?
presence of stored lipids esp cholesterol and fatty acids
Masculinization of eternal genitalia in females infants
congenital adrenal hyperplasia, males infants will be normal and may go undetected. Later in childhood both sexes have rapid growth due to androgen excess. Can be correlated with enzymatic deficiencies of cortisol biosynthesis
Chrommaffin cells or pheochromocytes
endocrine cell sof the medulla of adrenal glands
innervation of medula of adrenal gland
preganglionic sympathetic
righ adrenal gland
located on upper pole of kidney, pyramidal shaped
left adrenal gland
lies between upper pole of kidney and renal vessesls, is crescent shaped
blood supply of adrenal glands
superior suprarenal artery from inferior phrenic and middle suprarenal artery from aorta and inferior suprarenal artery from renal.
what is the venous drainage of the surprarenal glands?
central suprarenal vein
Lymphaitc drainage of adrenals
lumbar nodes
what is produced in male interstitial cells
adrogens (testosterone is one)
Inhibin
another hormone produced by interstitial cells in males involved in maintaining normal sperm production
corpus luteum
remaining follicular cells that release estrogens and profestins esp. progesterone
Embryology of pituitary gland
oral ectoderm forms rathke's pouch and diencephalon forms infundibulum
what forms the adenohypohysis
aka anterior lobe of pituitary from cells on anterior surface of rathke's pouch
what forms pars intermedia
cells on posterior surface of rathke's pouch
what forms neurohyphysis
aka posterior lobe of the pituitary… from distal portion of infundibulum
Diseases of pituitary
1. excessive or insufficient secretion 2. pituitary tumor compresses surrounding structures
are the internal carotid artery or cranial nerves usually involved in pituitary tumor?
no neither are the laterally located cavernous sinuses
what type of opitic disturbance in pituitary tumor?
optic chiasma compression to bitemporal hemianopsia
supriorily a tumor may compress
the hypothalamus
inferior the a pitiuitary tumor may compress
it may excavate the hypophyseal fossa and enter the sphenoid sinus
regions of anterior lobe of pitiuitary
pars distallis and pars intermedia
posterior lobe o fpituitary serves as
a storage and release site for hormones
What does the posterior pitiutary contain
axons of the hypothalamic neurons in supraoptic and paraventricular nuclei
pituicytes
post synaptic terminal cells in posterior pituitary
adh is manufactured in
supraoptic
oxytocin in manufactured in
paraventricular nucleus
blood supply of hypothalamus and hypophysis
hypophseal portal system
blood supply of hypophysis
superior and inferior hypohyseal artires
anterior lobe of pituitary blood supply
sinusoids of hypohyseal portal vessels
how does the hyopthalamus influence the hypohpysis?
via humoral substances (releasing hormones) that reach the anterior lobe via the portal system
where is th epineal gland located
dorsal aspect of the diencephalon, it is part of th eepithalamus
what is the pineal gland's primary secretion
melatonin
what stimulates the pineal gland
light via collateral fibers from the visual pathway---- SAD