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71 Cards in this Set
- Front
- Back
where does the embryology of they thyroid gland begin??
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As an epithelial proliferation at the juncture between the anterior 2/3 and posterior 1/3 of the tongue… later the forame cecum
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What is the the theyroglossal duct
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canal that connects thyroid to tongue during thryroid migration
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where is a thryroglossal cyst found
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at any point along the migratory path of the thryroid gland… always near or in the midline of th eneck. 50% are close to or inferior to the body of the hyoid bone
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what is the ultimobranchial body?
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a remnant of the 5th pharyngeal pouch that gives rise to the parafollicular or C cells of the thryorid gland that secretee calcitonin
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what does the isthmus cover
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2nd 3rd and 4th tracheal rings
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Where do the lateral lobes of the thryoid exted to?
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attachments of the sternothyroid muscles
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What do the sternothyroid muscles prevent
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the upward pathologic enlargment of the theyroid gland.
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what can enlargements of the medial portion of the thyroid gland affect?
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trachea, esophagus and recurrent and external laryngeal nerves
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what are the main blood suplliers to the theyroid
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superior and inferior, sometimes thyroid ima
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what is the thyroid ima abranch of
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usually brachio cephalic trunk
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where to the superior and middle thyroid veins drain to?
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internal jugular
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where does the inferior theyroid vein drain to?
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brachiocephalic
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where does the lymphatic drainage of the thyroid gland go
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ultimately deep cervical lymph nodes
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how is autonomic nerve supply provided to the thyroid gland?
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via direct branches from the sympathetic chain
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Where do the parathyroid glands arise from
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Epithelium of the third pharyngeal pouch yeild inferior parathyroid glands and the thymus the fourth pharngeal pough forms the superior parathyroid glands
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what is the arterial, venous and lymphatic supply of the thrymus
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Inferior thyroid arteries and internal thoracic arteries; inferior theyroid and brachiocephalic veins; and tracheobronchial and superior mediastinal nodes
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Specific location of the superior parathryoids
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Posterior surface of the thrydoid gland, anterior to the false capsule of the thyroid
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Specific location of the inferior parathryoids
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Posterior surface of the thrydoid gland, posterior to the false capsule of the thyroid
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how can parathyroid tumors be found in the thorax?
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The primordia of the thymus gland does not release the inferior parathryoid.
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what is the venous, lymphatic and autonomic nerve supply of the parathyroid
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same as the thyroid
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Which parathyroids are more easily injured durin ga thyroidectomy
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The superior b/c they're anterior to the "false capsule" and the left b/c they lie closer to the tracheo-esophogeal groove
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What forms the pancreas
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the dorsal and ventral pancreatic buds originating from the endodermal lining of the duodenum
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When the duodenum rotates to the right where does the ventral pancreatic bud move?
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dorsally
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What forms the uncinate process
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ventral bud (also the head) rest of the pancreas is dorsal bud
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When are islets of langerhans developed?
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3rd month of fetal life
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where are the islets of langerhand sfound?
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throughout the pancreasst but majority in tail and adjacent body
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What does the head of the pancreas lie on?
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inferior vena cava and renal veins
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Pt. with painlesss jaundice
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may have a tumor in the head of the pancreas blocking the common bile duct
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What is posterior to the neck of the pancreas?
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portal vein- tumor may obstruct
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what does the body of the pancreas lie across
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aorta, inferior vena cava and the left renal vein and recheas the left kidney and supra renal gland
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pt. with bachache
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lesion of the body of pancrease… peptic ulcer epigastric pain now goes to back
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arterial supply of pancrease
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anterior and posterior arterial arcades from gastroduodenal and superior mesenteric vessels. Also spelic and left gastroepiploic
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Venous drainage of pancrease
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splenic vein and its tributaries
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Lymphaitc drainage of pancreas
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nodes adjacent to head, neck, body and tail
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Where is the suprarenal gnald derived from?
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outer mesoderm, inner medulla ectoderm of nerual crest
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at birth the suprarenal gland
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is bigger than the kidney; the primitive or fetal cortex makes up the bulk of the gland; but by 2nd week has lost 1/3 of weight due to losss of primitive cortex
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Zones of permanent cortex
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zona glomerulosa, sona fasciculata and zona reticularis, not complete until a baby is 3 years old
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Why is the cortex yellow?
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presence of stored lipids esp cholesterol and fatty acids
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Masculinization of eternal genitalia in females infants
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congenital adrenal hyperplasia, males infants will be normal and may go undetected. Later in childhood both sexes have rapid growth due to androgen excess. Can be correlated with enzymatic deficiencies of cortisol biosynthesis
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Chrommaffin cells or pheochromocytes
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endocrine cell sof the medulla of adrenal glands
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innervation of medula of adrenal gland
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preganglionic sympathetic
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righ adrenal gland
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located on upper pole of kidney, pyramidal shaped
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left adrenal gland
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lies between upper pole of kidney and renal vessesls, is crescent shaped
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blood supply of adrenal glands
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superior suprarenal artery from inferior phrenic and middle suprarenal artery from aorta and inferior suprarenal artery from renal.
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what is the venous drainage of the surprarenal glands?
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central suprarenal vein
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Lymphaitc drainage of adrenals
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lumbar nodes
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what is produced in male interstitial cells
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adrogens (testosterone is one)
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Inhibin
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another hormone produced by interstitial cells in males involved in maintaining normal sperm production
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corpus luteum
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remaining follicular cells that release estrogens and profestins esp. progesterone
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Embryology of pituitary gland
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oral ectoderm forms rathke's pouch and diencephalon forms infundibulum
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what forms the adenohypohysis
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aka anterior lobe of pituitary from cells on anterior surface of rathke's pouch
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what forms pars intermedia
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cells on posterior surface of rathke's pouch
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what forms neurohyphysis
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aka posterior lobe of the pituitary… from distal portion of infundibulum
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Diseases of pituitary
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1. excessive or insufficient secretion 2. pituitary tumor compresses surrounding structures
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are the internal carotid artery or cranial nerves usually involved in pituitary tumor?
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no neither are the laterally located cavernous sinuses
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what type of opitic disturbance in pituitary tumor?
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optic chiasma compression to bitemporal hemianopsia
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supriorily a tumor may compress
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the hypothalamus
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inferior the a pitiuitary tumor may compress
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it may excavate the hypophyseal fossa and enter the sphenoid sinus
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regions of anterior lobe of pitiuitary
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pars distallis and pars intermedia
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posterior lobe o fpituitary serves as
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a storage and release site for hormones
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What does the posterior pitiutary contain
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axons of the hypothalamic neurons in supraoptic and paraventricular nuclei
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pituicytes
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post synaptic terminal cells in posterior pituitary
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adh is manufactured in
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supraoptic
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oxytocin in manufactured in
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paraventricular nucleus
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blood supply of hypothalamus and hypophysis
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hypophseal portal system
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blood supply of hypophysis
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superior and inferior hypohyseal artires
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anterior lobe of pituitary blood supply
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sinusoids of hypohyseal portal vessels
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how does the hyopthalamus influence the hypohpysis?
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via humoral substances (releasing hormones) that reach the anterior lobe via the portal system
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where is th epineal gland located
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dorsal aspect of the diencephalon, it is part of th eepithalamus
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what is the pineal gland's primary secretion
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melatonin
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what stimulates the pineal gland
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light via collateral fibers from the visual pathway---- SAD
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