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14 Cards in this Set

  • Front
  • Back
Hypothalamus and pituitary gland
- form a unit regulating the release of hormones from other "peripheral glands"
Negative feedback loops

Problems
-maintain the hormones from the peripheral glands wtihin a range associated with normal regulation of functions

-problems: mild dysfunction to incapacitatind disease may result if one of these hormones is out of normal range
Delivery of hypotalamic factors controlling the anterior pituitary is via...
portal circulation
Delivery of hypothalamic factors regulating theposterior pituitary is via..
supraoptic and paraventricular neurons
"primary"
- if pathological amt of hormone arises from dysfunction in the peripheral gland making the hormone
"secondary"
- if cause arises form a pathology in the pituitary, the hypothalamus, or elseware
"inappropriate relationship"
- if hormone level is not in the normal range, and apituitary hormone promoting its release is in the normal range, then the level of the pituitary hormone may not be approrpiate
- may indicate a pathology is present in the pituitary or in a mechanism regulating pituitary function
Hypothesis that hypothalic hormones that regulate anterior pituitary function
- hypothalamic hormones acting on the anterior pituitary may have other functions (not accepted yet/future)
PRF: Prolacting Releasing factor

(Hypothalamus)
+Prolactin--> Breast

DA: Dopamine --> neg Prolactin

(Anterior Pituitary)
GnRH: Gonadotrophin RH

(Hypothalamus)
+ FSH: Follicle stimulating H+ --> gonads

+LH: Lutenizing Hormone --> gonads


(Anterior Pituitary)
TRH: Thyrotropin RH

(Hypothalamus)
+ TSH: Thyroid stimulating hormone --> Thyroid


(Anterior Pituitary)
CRH: Corticotropin RH

(Hypothalamus)
+ ACTH: Adrenocorticotrophic hormone --> Adrenal cortex


(Anterior Pituitary)
GHRH: Growth Hormone Releasing Hormone

(Hypothalamus)
+ GH: Growth hormone --> liver and other tissues

SS: Somatostatin --> neg Growth hormone


(Anterior Pituitary)
Supraoptic and Paraventricular neurons

(Hypothalamus)
Oxytocin --> uterus, breast

ADH: Antidiuretic hormone or vasopressin --> Kidneys and blood vessels

(Posterior pituitary)