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97 Cards in this Set

  • Front
  • Back
the endocrine system is....
the sub system of the nervous system that controls smooth and cardiac muscle and glands
what is a unique part of the Autonomic system
the autonomic ganglion
autonomic ganglion
a mass of nerve tissue outside the cns that contains cell bodies.
The ANS has 2 subdivision
sympathetic parasympathetic
the sypathetic system
part of the ANS - fight or flight. Allows body to deal with extreme situations that would knock it out of homeostasis
What are the symptoms of a sympathetic response
The are rapid.

rapid breathing
increased heart rate
increased blood pressure
dry mouth
dialated pupils
constricted bladder
decrease in peristalsis
peristalsis
food moving through gi tract
where does the sympathetic division originate from
T1-L2 Its the thoraculmnar outflow
where is the ganglion in the sympathetic system
always in front or next to the SC.
What are the terms for in front and next to for the ganglion
prevertabral - in front
paravertabral - on side
What is the major function of the endocrine system
to maintain homeostasis
The majority of homones in the endocrine system are released using
negative feedback loops
The nervous system works by
conduction action potentials that trigger the release of neurotransmitters at a synapse
the endocrine system works by
releasing chemicals called hormones
the effects of the nervous system vs the endocrine system
the nervous system has short term effects the endocrine system has long term
The nervous system and the endocrine system generally work...
together. The control every function in the body
Hormones are...
chemical messengers released by endocrine glands
What do hormones affect
cells somewhere else in the body
Target cell
any cell affected by a hormone
hormones produce ________ responses than
slower

than the nervous system
what is the time for hormones to work
some work in a couple of seconds but most take a couple of minutes
The affects of the endocrine system tend to be much
broader than the nerovous system
Why are the affects of the endocrine system broader than the nervous system
hormones can affect all types of body cells.
Describe the super system
The nervous system and the endocrine system working together. The nervous system will stop or start the release of hormones
What does the release of hormones cause
the generation of action potentials.
exocrine glands
produce a product secreted into a duct and then the duct carries the product into cavities, organs or onto a surface.
What are 4 examples of an exocrine gland
digestive, mucous, sebacous, sudoriforous glands
endocrine glands
secrete hormones into the blood and then the blood carries them through the body.
what is 4 examples of endocrine glands
thyroid pituitary adrenal pineal
some glands even though they are not endocrine glands.... (what are they)
secrete hormones.

pancreas kidneys liver stomach small intestines skin heart placenta testes ovarys
hormones will only affect
target cells and will ignore all other cells
hormone receptor
a protien on the surface of the target that the hormone binds to
only target cells have
hormone receptors
usually targets have _________ receptors for a given hormone
2000-100,000
Down regulation occurs...
if the amount of a hormone is excessive in the blood
Down regulation causes
the number of protien receptors for that hormone to decrease on the target cell
Up regulation occurs
whne the hormone levels in the blood are low.
Up regulation causes
the number of protien receptors on the target cell to increase
down regulation makes the target...
less responsive to the hormone.
up regulation makes the target...
more responsive
What are the 2 general types of hormones
circulating- leae the cell that produced them and they enter the blood stream

local - act on the cell that made them or on a neighboring cell but do not enter the blood stream
which type of hormone does not enter the blood
local
what are the 2 types of local hormones
paracrines- act on neighboring cells
autocrines - act on the cell the made it
What are the 2 classes of hormones
lipidsoluble- easily diffuse through the cell membrane

water soluble- cannot diffuse through on their own.
Examples of lipid soluble hormones
steroids
thyroid hormones
nitrisoxide
Steroids
a type of lipid soluble hormone - testoerone, estrogen. Which have diverse funtions produced from cholesterol and have a unique 4 ring structure
thyroid hormones
produced from T3 and T4. produced from amino acid tyrosine
Nitricoxide
released by cells lining blood vessles causes vasodialation which increases blood flow to a region
Examples of water soluble hormones
amines
protiens and peptides
eicosanoids
amines
simplest of all hormones histamine seratonin melatonin
protiens and peptides always have
betwen 3 and 200 amino acids
eicosanoids
a 2D carbon fatty acid (arachiadonic acid) phostoglandins and leukotrines
Describe hormones action
They most always annoucnce their arrival to the target cells by binding to protien receptors on the targets surface or inside the target.
if the hormone is lipid soluble the receptors ....
are inside
if the hormone is water soluble the receptors are
outside
lipid soluble hormones work by
direct gene activation they diffuse through the membrane and bind to the receptors that will activate or deactivate DNA
water soluble hormones act by
using 2nd messengers
What is the 1st messenger in water soluble action
water soluble hormone
G protien is located.
is on the surface of the target cell, and is what the water soluble hormone binds to
The g protien activates
adenolate cyclase
adenolate cyclase is...
a group of enzymes on the inner membrane of the target
Adenolate cyclase activates..
ATP
After ATP is activated what does the ATP activate
cAMP
cAMP activates
protien kinases
protien kinases
a group of protiens inside the target. Depending which ones are activated they will determine how the target cell reacts to the hormone. causing it to secrete or stop secreteing.
phosphodiesterase
another enzyme that is activated that inactivates cAMP stopping the process
Most hormones are secreted in...
short bursts
when it is the endocrine gland is activley stimulated a hormone secretes...
more frequently leading to down regulation.
What leads to up regulation
when the endocrine gland is not being stimulated the hormone levels drop
What are the 3 things that help regulate secretion of a hormone
nervous system chemical changes in blood or other hormones
The autonomic system has
many axon colaterals so sypathetic effects are wide spread
the parasympathetic is system
is the housekeeping system. Its alwas active when things are normal. Its refered to as feed or breed
The autonomic ganglion is located
next to or in the effector
the post ganglionic fiber is
short thin unmylenated and also releases ACH. Its the terminal ganglion. little axon branching
effecs are not wide spread
parasympathetic seffects are
opposite of sympathetic
The type of NT release is used to
classify autonomic fibers
skin produces
vitamin D
lungs produce
angiotensin II
heart produces
atrial natrieuretic peptide
liver and kidneys produce
erythropoietin
leukopoietin
thrombopoietin
testes produce
testosterone, inhibin
ovaries produce
estrogetn
progestrone
relaxin
inhibin
stomach produces
gastrin
small intestine produces
cholecystokinin (cck)
gastric inhibitory peptide
vitamin D
bone growth development and repair
angiotensisn II
raises blood pressure by affecting the kidney
atrial natrieuretic peptide ANP
affects filtration rate int he kidney and raises bp
erythropoietin
makes read blood cells
leukopoietin
makes white blood cells
thrombopoietin
makes platlets
testoterone
makes sperm and produces masculine sex charactersitics
inhibin
stops secretion of FSH
estrogen and progesterone
maintain menstrual cycle maintain pregnancy and produce 2ndary sex characteristics of a female
relaxin
makes symphasis pubis more flexible during deliver and dilates cervix
gastrin
causes stomach emptying
CCK cholecystokinin
causes the release of bile and pancreatic juice
gastric inhibitory peptide
slows down stomach emptying