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97 Cards in this Set
- Front
- Back
the endocrine system is....
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the sub system of the nervous system that controls smooth and cardiac muscle and glands
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what is a unique part of the Autonomic system
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the autonomic ganglion
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autonomic ganglion
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a mass of nerve tissue outside the cns that contains cell bodies.
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The ANS has 2 subdivision
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sympathetic parasympathetic
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the sypathetic system
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part of the ANS - fight or flight. Allows body to deal with extreme situations that would knock it out of homeostasis
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What are the symptoms of a sympathetic response
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The are rapid.
rapid breathing increased heart rate increased blood pressure dry mouth dialated pupils constricted bladder decrease in peristalsis |
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peristalsis
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food moving through gi tract
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where does the sympathetic division originate from
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T1-L2 Its the thoraculmnar outflow
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where is the ganglion in the sympathetic system
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always in front or next to the SC.
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What are the terms for in front and next to for the ganglion
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prevertabral - in front
paravertabral - on side |
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What is the major function of the endocrine system
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to maintain homeostasis
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The majority of homones in the endocrine system are released using
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negative feedback loops
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The nervous system works by
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conduction action potentials that trigger the release of neurotransmitters at a synapse
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the endocrine system works by
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releasing chemicals called hormones
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the effects of the nervous system vs the endocrine system
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the nervous system has short term effects the endocrine system has long term
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The nervous system and the endocrine system generally work...
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together. The control every function in the body
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Hormones are...
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chemical messengers released by endocrine glands
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What do hormones affect
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cells somewhere else in the body
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Target cell
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any cell affected by a hormone
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hormones produce ________ responses than
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slower
than the nervous system |
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what is the time for hormones to work
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some work in a couple of seconds but most take a couple of minutes
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The affects of the endocrine system tend to be much
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broader than the nerovous system
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Why are the affects of the endocrine system broader than the nervous system
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hormones can affect all types of body cells.
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Describe the super system
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The nervous system and the endocrine system working together. The nervous system will stop or start the release of hormones
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What does the release of hormones cause
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the generation of action potentials.
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exocrine glands
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produce a product secreted into a duct and then the duct carries the product into cavities, organs or onto a surface.
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What are 4 examples of an exocrine gland
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digestive, mucous, sebacous, sudoriforous glands
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endocrine glands
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secrete hormones into the blood and then the blood carries them through the body.
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what is 4 examples of endocrine glands
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thyroid pituitary adrenal pineal
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some glands even though they are not endocrine glands.... (what are they)
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secrete hormones.
pancreas kidneys liver stomach small intestines skin heart placenta testes ovarys |
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hormones will only affect
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target cells and will ignore all other cells
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hormone receptor
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a protien on the surface of the target that the hormone binds to
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only target cells have
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hormone receptors
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usually targets have _________ receptors for a given hormone
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2000-100,000
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Down regulation occurs...
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if the amount of a hormone is excessive in the blood
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Down regulation causes
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the number of protien receptors for that hormone to decrease on the target cell
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Up regulation occurs
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whne the hormone levels in the blood are low.
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Up regulation causes
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the number of protien receptors on the target cell to increase
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down regulation makes the target...
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less responsive to the hormone.
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up regulation makes the target...
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more responsive
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What are the 2 general types of hormones
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circulating- leae the cell that produced them and they enter the blood stream
local - act on the cell that made them or on a neighboring cell but do not enter the blood stream |
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which type of hormone does not enter the blood
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local
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what are the 2 types of local hormones
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paracrines- act on neighboring cells
autocrines - act on the cell the made it |
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What are the 2 classes of hormones
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lipidsoluble- easily diffuse through the cell membrane
water soluble- cannot diffuse through on their own. |
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Examples of lipid soluble hormones
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steroids
thyroid hormones nitrisoxide |
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Steroids
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a type of lipid soluble hormone - testoerone, estrogen. Which have diverse funtions produced from cholesterol and have a unique 4 ring structure
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thyroid hormones
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produced from T3 and T4. produced from amino acid tyrosine
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Nitricoxide
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released by cells lining blood vessles causes vasodialation which increases blood flow to a region
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Examples of water soluble hormones
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amines
protiens and peptides eicosanoids |
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amines
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simplest of all hormones histamine seratonin melatonin
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protiens and peptides always have
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betwen 3 and 200 amino acids
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eicosanoids
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a 2D carbon fatty acid (arachiadonic acid) phostoglandins and leukotrines
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Describe hormones action
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They most always annoucnce their arrival to the target cells by binding to protien receptors on the targets surface or inside the target.
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if the hormone is lipid soluble the receptors ....
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are inside
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if the hormone is water soluble the receptors are
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outside
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lipid soluble hormones work by
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direct gene activation they diffuse through the membrane and bind to the receptors that will activate or deactivate DNA
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water soluble hormones act by
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using 2nd messengers
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What is the 1st messenger in water soluble action
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water soluble hormone
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G protien is located.
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is on the surface of the target cell, and is what the water soluble hormone binds to
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The g protien activates
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adenolate cyclase
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adenolate cyclase is...
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a group of enzymes on the inner membrane of the target
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Adenolate cyclase activates..
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ATP
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After ATP is activated what does the ATP activate
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cAMP
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cAMP activates
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protien kinases
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protien kinases
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a group of protiens inside the target. Depending which ones are activated they will determine how the target cell reacts to the hormone. causing it to secrete or stop secreteing.
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phosphodiesterase
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another enzyme that is activated that inactivates cAMP stopping the process
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Most hormones are secreted in...
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short bursts
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when it is the endocrine gland is activley stimulated a hormone secretes...
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more frequently leading to down regulation.
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What leads to up regulation
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when the endocrine gland is not being stimulated the hormone levels drop
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What are the 3 things that help regulate secretion of a hormone
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nervous system chemical changes in blood or other hormones
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The autonomic system has
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many axon colaterals so sypathetic effects are wide spread
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the parasympathetic is system
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is the housekeeping system. Its alwas active when things are normal. Its refered to as feed or breed
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The autonomic ganglion is located
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next to or in the effector
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the post ganglionic fiber is
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short thin unmylenated and also releases ACH. Its the terminal ganglion. little axon branching
effecs are not wide spread |
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parasympathetic seffects are
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opposite of sympathetic
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The type of NT release is used to
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classify autonomic fibers
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skin produces
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vitamin D
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lungs produce
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angiotensin II
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heart produces
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atrial natrieuretic peptide
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liver and kidneys produce
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erythropoietin
leukopoietin thrombopoietin |
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testes produce
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testosterone, inhibin
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ovaries produce
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estrogetn
progestrone relaxin inhibin |
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stomach produces
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gastrin
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small intestine produces
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cholecystokinin (cck)
gastric inhibitory peptide |
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vitamin D
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bone growth development and repair
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angiotensisn II
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raises blood pressure by affecting the kidney
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atrial natrieuretic peptide ANP
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affects filtration rate int he kidney and raises bp
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erythropoietin
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makes read blood cells
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leukopoietin
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makes white blood cells
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thrombopoietin
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makes platlets
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testoterone
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makes sperm and produces masculine sex charactersitics
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inhibin
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stops secretion of FSH
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estrogen and progesterone
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maintain menstrual cycle maintain pregnancy and produce 2ndary sex characteristics of a female
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relaxin
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makes symphasis pubis more flexible during deliver and dilates cervix
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gastrin
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causes stomach emptying
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CCK cholecystokinin
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causes the release of bile and pancreatic juice
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gastric inhibitory peptide
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slows down stomach emptying
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