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6 Cards in this Set
- Front
- Back
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who created insulin
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Banting and Macloed
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first person to receive insulin
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Leonard Thompson- 14- yo
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key concepts for T1D
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-genetic and famial clustering
-presence of high-affinity auto-abs and T cells - strong HLA association -recurrence of disease in pancreas transplanted b/w identical twins |
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T1D is characterized by what
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immune-mediated destruction of pancreatic beta cells resulting in insulin deficiency
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patients with T1D are prone to what
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ketoacidosis-- high levels of ketones in blood
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onset of T1D is associated with what
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infiltration of islets of Langerhans by monuclear cells and CD 8 T cells
-termed insulitis |
