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15 Cards in this Set

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Sx:
-low FSH, LH, ACTH, TH, GH
-high PRL

Dx?
hypothalamic lesion or compression of pit stalk
how do pt with hypothalamic lesion present?
all ant pit hormones are low, except PRL (incr PRL)
how do pt w/compression of pit stalk present?
all ant pit hormones are low, except PRL (incr PRL)
all pit hormones are low

Dx?
hypopituitarism
Tx person with low TH and high PRL?
-they have high PRL d/t hypothy.

Tx underlying thyroid condition, not hte PRL levels!
which hormones are secreted in pulsatile manner?
all ant pit hormones
when is TSH secretion highest?
from midnight til early morning
low Na
high K
hyperpigmented
prinary AI (Addison's Dz)
Tx hypopituitariam
replace end organ hormone
hypopituitarism
-et?
1. pituitary tumor destroys pituitary

2. Empty Sella Syndrome
--defect in diaphragma sella
==>pit gland replaced by CSF

3. Pituitary apoplexy
--hemorrhage into pituitary tumor
regulation of GH sretion
-GH-RH stimulates
-somatostatin inhibits
systemic effects of acromegaly
1. MCCoD= cardiomegaly/cardiomyopathy
2. HTN
3. DM/insulin rsistance
4. colonic polyps
5. arthritis
6. skin tages
7. incr bone turnover
8. galactorrhea
Sx of Hyperprolactinemia
Women:
-amenorrhea
-galactorrhea

Men:
impotence
what causes central DI?
injure hypothalamus (produces ADH) or pituitary stalk (ADH and oxytocin travel down pit stalk to get to target organ)
causes of polyuria
1. DI
2. high Ca++ and low K+ (always check serum electrolytes!)