Endo-Ics-Hypoglycemia

Front 1

-below what BG do Sx of hypoglycemia occur?
-when does impaired cognitive fxn occur (cna't concentration, hard to speak, blurred vision)

Back 1

-Sx of hypoglycemia when BG<55
-impaired cognitive fxn when BG<50

Front 2

def of hypoglycemia

Back 2

*after 8-10 hr of overnight fast:
-plasma glucose<60
-blood glucose<50

*anytime:
-plasma glucose<50
-blood glucose<40

Front 3

***Whipple's triad of clinically-significant hypoglycemia

Back 3

1. Sx with simultaneous documentation of
2. *biochemical hypoglycemia that
3. improve or disappear following ingestion of carbs

*Biochemical hypoglycemia:
--AFter 8-10 h overnight fast:
~plasma glucose<60
~blood glucose<50

--Anytime
~plasma glucose<50
-blood glucose <40

Front 4

drugs that cause hypoglycemia

Back 4

MCC=insulin
2nd MCC=sulfonylureas (glipizide, gliburide, glimepiride)

Front 5

nl vs abnl response to OGTT

Back 5

OGTT=75 grams of oral glucose

nl response: peak glucose and insulin are both 1 hr after intake

abnl: insulin peak is 2 hrs after (thus, not soon enough, BG already high)