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26 Cards in this Set

  • Front
  • Back
Nitroglycerin

pharmacology & actions
NTG/Nitro

1. Cardiovascular effects
A. Reduced venous tone causes pooling in periph veins, decreased blood return to heart
B. decreased periph resistance
C. Dilation of coronary arteries

2. Generalized Smooth Muscle Relaxation
NTG

indications
A. angina

B. cx, arm or neck pain thought possibly to be related to coronary ischemia, can be used diagnostically

C. pulmonary edema: to increase venous pooling lowering cardiac preload & afterload

D. Food impaction located in the esophagus (may relieve muscle spasm)
NTG

precautions and side EFX
A. throbbing H/A, flushing, dizziness, ad burning under the tongue

B. marked hypotension, NTG contraindicated if any ED meds on board from last 24 hours (doctor call in)

C. generalized vasodilation may cause reflex tachy

D. less then 90 systo
NTG

admin
Standing order
Cx Pn
0.4 mg (1/150 grain) SL spray or tab
total 3 dose every 5 min

Nitropaste 2 inches to cx wall by standing order if needed

Pulmonary Edema
0.4mg (1/150grain) SL spray or Tab
may then apply nitropaste: 2inches to cx wall

OR

1 NTG every 3-5min X 2 (total 3)

Food Impaction
0.4 mg SL spray or Tablet
-repeat by MD order
NTG

special notes
A. use with caution in hypotensive pt

B. upright may increase threapuetic effect as well as adverse effects
NTG

Storage
loose potency easily, should be stored in a dark glass container with a tight lid, and not exposed to heat
Aspirin

pharmacology & actions
ACETYLSALICYCLIC ACID / ASA

A. In 2mg/kg oral or IV doses, produces rapid antithrombolic due to inhibition of Thromboxane A2

B. All platelets in circulation are inhibited by ASA at the time of exposure. life span 8-10 days, 5 days later 50% platelets inhibited
ASA

Indications
A. anticoagulant effect, ASA therapy should be given as soon as possible after the onset of cardiac Cx Pn in MI cases

B. Associated symptoms of suspected MI: nauseau, SOB, diaphoresis, palpitations
ASA

precautions & side effects
contraindications

1. allergy to ASA
2. active bleeding
ASA

Admin
Cardiac Cx Pn
Standing order

4 X 81 mg cheqable tabs (baby ASA) total 324 mg, have pt chew ASA completely

IF PT HAS TAKEN 324 MG IN THE LAST 2 HOURS, DO NOT ADMIN
Dopamine

Indications
INTROPIN

1. cardiogenic shock
2. other shock (NOT hypovolemia)
Dopamine

precautions and side effects
A. may induce tachyarrhythmias (decrease or stop infusing)

B. high doses cause extreme periph vasoconstriction, low doses = low bp due to periph dilation

C. antidepressents, sympathomimetics potentiate effects

D. inactivated by sodium bicarb or other alkaline solutions
Dopamine

admin
MD ORDER

start at 10mcg/kg/min
2-20mcg/kg/min
Dopamine

Notes
A. most common side effects include ectopic beats, n/v angina

B. hypertensive crisis in some individuals

C. treat hypovolemia first, contraindicated for hypovolemic shock
Fentanyl

pharmacology & actions
SUBLIMAZE

A. synthetic opiod analgesic
100mcg fent = 10mg morphine

B. Does not cause hypotension

C. Duration
30-60 min IV
60-120 min IM
Fent

Indications
A. Pain
1. best choice when hypotension is a concern
2. when short term analgesia is preferred

B. RSI treatment
1. Adjunct for sedation, blunts ICP elevations
Fent

Contraindications
patients with known intolerance to fent (rare)
Fent

Precautions
A respiratory depression
1. peak effect/respiratory depression occurs 5-15 min after IV dose
2. pts should be on continuous pulse ox

B. synergistic effects concomitant benzodiazepine admin (versed)

C. In large dose and rapid admin, may cause muscle rigidity (respiratory muscles) EMERGENCY = SUXX do not use narcan

D. use reduced dose in the elderly, debilitated
Fent

side effects
A. may cause N/V

B. Will cause Miosis (pupilary constriction)
Fent

Admin
STANDING ORDER

A. Narcotic Analgesia
1. 50 mcg = 1cc
2. Adult
50-100mcg IV/IM [SLOWLY over 1-2min]

start with 25-50mcg in elderly/debilitated

administer in 50-100mcg increments minimum every 5 min

Call above 300 MCG

Peds
Standing Order
1mcg/kg repeat in 10 min
Fent

Notes
Rapid IV admin may cause cx wall rigidity leading to respiratory depression or apnea seen 5-15 minutes after admin
Morphine Sulfate

pharmacology and action
MS

A. Analgesia

B. Pupil Constriction

C. Respiration: decreased rate and tidal volume

D. Periperal vasodilation
1. causes no problems if supine and not volume-diluted
2. May cause problems if
a. upright
b. hypovolemic
c. decreased cardiac output (after MI)

3. Cardiac effect of vasodilation
a. Decreases myocardial O2 consumption
b. Decreases LV End Diastolic Pressure
c. Decreases cardiac work
d. May increase incidence of arrhythmias

Max effect within 7 min IV
MS

Indications
Use in management of acute pain
MS

Precautions and Side Effects
A. Hypotension is a contraindication to use. pn causes hypotension (consult MD)

B. Use Fent in pts with abdominal pain

C. Use with caution in patients with respiratory difficulties, because their respiratory drive must ot be depressed

D. Do not use with major blood loss

E. May cause vomiting, administer slowly
MS

Admin
Standing Order
Adult
0.1 mg/kg starting dose typically 5mg IV or IM
repeat every 5-10 minutes
Administer up to 20mg without MD consultation

Peds
Standing order
0.1-0.2 mg/kg IV or IM
MS

Special Notes
side effects are more pronounced in elderly patients, give slowly and have bvm and narcan available