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35 Cards in this Set
- Front
- Back
Diazepam
-Drug Class -Actions |
Class-
Anticonvulsant & Sedative & Muscle Relaxant (Benzodiazepine) Actions- Anticonvulsant, Depresses C,P,A nervous systems, Decreases patient recall (amnesic effect) |
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Diazepam
-Indications -Contraindications |
Indications
-Active seizure activity -sedation prior to cardioversion -Prevent/suppress seizure caused by organophosphate poisoning Contra- Shock/hypotension -Alcohol intoxication(synergist) -Acute narrow angle glaucoma ----rel. contra.Head Injury (decreased CNS Function)--- |
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Diazepam
-Adverse effects |
Cardio
-tachycardia, bradycardia, hypotension Respiratory -Apnea, hypoventilation Neuro -Blurred Vision, dizziness, confusion, restlessness, slurred speech Other- worsens glaucoma, Phlebitis |
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Diazepam
-Administration |
5-10mg IVP at 5mg per minute. Titrate to stop seizure activity or until sedation occurs for cardioversion. MR 5mg/min PRN to 20mg
ORGANOPHOSPHATE nerve agent severe poisoning 10 mg IM one time via auto-injector or syringe after mark I has been administered |
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Diazepam
-peds Admin |
0.1-0.3 mg/kg IVP at 1 mg per minute or 0.5 mg/kg PR
-Titrate IV dose to stop seizure activity or until sedation occurs for cardioversion. MR IVP dose PRN up to 5mg(for up to 5yo) and 10mg (older than 5yo ORGANOPHOSPHATE nerve agent, severe poisoning-0.2mg/kg IVP or IM. Max single dose 2mg. Max all dose 10mg |
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Diazepam
-Precautions -Rationale |
(P)Establish largest bore cannula in large vein and run IV wide open while administering medication (R)Drug may cause pain warmth or burning at IV site. Pt. may develop phlebitis, sclerosis or thrombosis of vein
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Diazepam
-Precautions -Rationale cont |
(P) Support respirations (R) May cause respiratory depression
(P)Start NORMAL SALINE IV (R) Diazepam microprecipitates in D5W (P) Inject med as close to IV as possible (R) diazepam is easily absorbed by plastic reducing concentration (P)Flush line before and after med (R) incompatible w/ other meds (P) Administer SLOWLY to elderly (R) Geri's have increased incidence of adverse effects |
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Diazepam
-Note |
May be given for focal seizures if patient has ALOC. May alter Alter LOC. Use caution with pt.'s with head injury. Antidote for respiratory depression is Romazicon (flumazenil)...seizure... Schedule IV storage and records
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Morphine Sulfate
-class -action |
Class- Narcotic Analgesic
Actions- Alters pain perception and produces euphoria Depresses central nervous system by interacting with opiate receptors in the brain Decreases myocardial oxygen demand by: Decreasing preload by causing venous pooling due to peripheral vasodilation, Decreasing afterload by causing peripheral vasodilation resulting decreased systemic vascular resistance |
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Morphine Sulfate
-indications |
Moderate to severe pain, **Especially burns or isolated extremity trauma
Chest pain of suspected myocardial origin Pulmonary edema (not in LA) |
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Morphine Sulfate
-contraindications |
Hypotension-Hypovolemia
Increased ICP- Head Injury Patients at risk for respiratory depression (COPD) |
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Morphine Sulfate
-Adverse affects |
Cardiovascular
-Tachycardia, Bradycardia -HYPOTENSION Respiratory -bronchospasms -apnea -RESPIRATORY DEPRESSION GI- n/v!!! Neuro -blurred vision, dizziness, hallucinations, confusion Other -ITCHING -flushing (red line from IV...histamine response) |
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Morphine Sulfate
-Administration |
2-10mg SLOW IVP at 2mg/min. Titrate to relief of pain. May repeat IV dose PRN to a maximum of 20mg
5-10mg IM as a single dose |
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Morphine Sulfate
-Admin Peds |
0.1mg/kg slow IVP at 2mg/min. Titrate to relief of pain
0.1mg/kg IM as a single dose |
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Morphine Sulfate
-Precautions/Rationale |
(P)Have Naloxone available (R) will reverse the respiratory depression caused by MS
(P) Monitor Vital Signs (R) May cause histamine mediated hypotension. Use shock position and/or fluids to treat hypotension. May cause hypotension in volume depleted or right ventricular infarction patients. (P) Mix 10mg (1ml) Morphine w/ 9ml of NS to produce a concentration of 1mg/1ml |
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Morphine Sulfate
-Note |
Morphine Sulfate is a schedule II med and will require additional storage and record keeping
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Morphine Sulfate
-Ref 806 |
Moderate to severe pain due to ISOLATED extremity injury or burn
Titrate 2-4mg IV/IM if SBP >100 MRx1 PEDS- 0.1mg/kg IV/IM max single dose 4mg. MRx1 |
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Nalaxone
-class -Actions -Indications -contraindications |
Narcan
class-Narcotic antagonist Actions- reverses the respiratory and CNS sedation of narcotics by competing for opiate receptor sites in the brain Indications- Suspected Narco OD with RR<12 or decreased TV Contraindicaitons- not significant in indications listed above |
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Naloxone
-Adverse Effects |
Cardio
-tachycardia -dysrhythmias -hypertension GI- n/v!!! Neuro -tremors -seizures |
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Naloxone
-Admin |
0.8-2mg IVP,IM,IN. MR for all routes every 5min PRN. Titrate IV dose to adequate respiratory rate and tidal volume
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Naloxone
-Admin Peds |
0.1 mg/kg IVP, IM, IN MR dose for all routes every 5 min PRN
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Naloxone
-precautions -rationale |
(P) Monitor patient status continuously, repeated doses may be needed (R) Actions may be as short as 30 min and patients may relapse into resp. depression.
(P) Administer med before consider ET intubation. (R) Patient will wake up and be pissed (P)Recovery position, have suciton available (R) Protect Airway (P) Monitor Vital Signs (does not reverse narcotic induced hypotension. Treat with shock position and fluids (P) Prepare to protect pt. and EMS personnel (R)you just stole a junky's buzz |
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Naloxone-
-Note...Reverses the Narcotics... |
MS, heroin, hydromorphone (vicodin), methadone, oxycodone (oxycontin) fentanyl citrate, paregoric, codeine, propoxyphene
AND Reverses narcotic agonist-antagonist -butorphanol tartrate, pentazocine (talwin), nalbuphine (nubain) |
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Naloxone-
Supplied |
4mg/10ml vial: 2mg/2ml pre-fill syringe
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Naloxone-
Ref 806 |
Resp Distress- Arrest/Hypovent (RR<_8min) Adult-0.8mg -2mg IV/IM MR PRN... Ped- 0.1 mg/kg IV/IM MR PRN
Altered LOC- Suspected narcotic OD w/ hypoventilation (prior to ET) Adult- 0.8-2 mg IV/IM....Ped- 0.1 mg/kg IV/IM |
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Midazolam HCl
-Class -Actions |
(Versed Hypnoval)
Class -Anticonvulsant, Sedative, Hypnotic (Benzodiazepine) Actions -Depresses CNS -Relaxes skeletal muscles -Decreases patient recall (amnesic effect) |
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Midazolam HCl
Indications |
-Suppression of Seizure activity
-Sedation prior to cardioversion/TCP -Facilitates intubation -Agitated Delirium (ETOH and/or drug Pt. ^BP, ^HR, ^Resp from surges of acetylcholamine |
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Midazolam HCl
-Contraindications |
Contra
-Glaucoma -Shock-Hypotension -Patients taking calcium channel blocker or antifungal meds Relative contra -Head Injury -Alcohol intoxication |
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Midazolam HCl
-Adverse Effects |
Cardio
-tachycardia -bradycardia -HYPOTENSION -PVC's Respiratory -apnea, HYPOVENTILATION, laryngospasm, bronchospasm, hiccups Neuro -Blurred vision, dizziness, drowsiness, confusion, restlessness, amnesia Other -Phlebitis |
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Midazolam HCl
-Admin Adults |
Sedation for TCP or Cardioversion
1-2 mg SLOW IVP at 1mg/min. Titrate to produce sedation. 2.5 mg IM or IN. Max total dose is 10 mg Seizure: 2-5mg SLOW IVPat 1mg/min. titrate to supress seizure activity. MR IVP every 3-5 min prn. 5mg IM or IN. MR IM/IN dose x1 in 5 min. Max dose 10mg Agitated delirium- 2-5mg slow IVP at 1mg/min. 5mg IM/IN MR x 1.Maximum total dose 10 mg. |
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Midazolam HCl
-Admin peds |
Seizure-
0.1mg/kg IVP at 1mg/min or 0.1mg/kg IM/IN. Titrate IV dose to suppress seizure activity. MR IVP/IM/IN dose x1 prn. Max total dose 5mg. |
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Midazolam HCl
-Precautions -Rationale |
(P) Monitor respiratory & cardiac status and prepare to support airway, ventilation & circulation. Have BVM and OP ready (R) Midazolam is 3-4x's more potent than diazepam...Significant risk of respiratory depression, especially w/ COPD pt.'s. (P) Continuous pulse ox (R) Monitor for hypoventilation
(P) Admin only 1/2 the recommended dose to debilitated pt.'s and pt.'s over 60yo (R) decreased hepatic metabolism prolongs the sedative effects. |
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Midazolam HCl
-Notes |
-Ped pt.'s may require higher doses than adults, and children<6yo may require more than 6-12yo because of different metabolism.
-The action of Midazolam is potentiated when pt.'s are taking verapamil, ditiazem, ketoconazole, itraconazole, narcotics or have alcohol intoxication. the synergistic effet may result in life threatening resp depression or dysrhythmias |
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Midazolam HCl
-Notes (cont) |
there is an increased risk of digoxin toxicity because of hypokalemia
- The antidote to reverse respiratory depression is Romazicon (flumazenil) -Midazolam is a schedule IV med and will have additional storage and record keeping reqs. |
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Midazolam HCl
-Ref 806 |
Active Seizure- Adult
- titrate 2-5 mg IVP to seizure control. IF unable to start IVP, 5mg IM or IN MRx1 Pediatric 0.1mg/kg IVP to seizure control MR. If unstable to start IV, 0.1mg/kg IM or IN MR x1 |