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12 Cards in this Set

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Hypocalcaemia

Prolonged QT interval

Causes of prolonged QT interval

Hypokalaemia, hypocalcaemia hypomagnesemia


Type 1A Antiarrhythmic drugs (quinidine procainamide)


Severe CNS abnormalities (i.e subarachnoid haemorrhage)

QT interval is associated with

Torsade de pointes ( Polymorphic ventricular tachycardia)

High altitude causes hyperventilation and respiratory alkalosis which leads to

Hypocalcemia due to enhanced calcium-albumin binding


An elevation in extracellular PH increases the binding of calcium to album and thereby lowering the plasma ionized calcium concentration

Succinylcholine associated with

Life-threatening malignant hyperthermia and hyperkalaemia in predispose patients

Succinylcholine is

A Muscle relaxant (a nicotine acetylcholine receptor agonist) popular for use in endotracheal intubation in emergency departments because if it’s fast effects and short term action

Dantrolene

Ryanodine receptor antagonist


Inhibits abnormal calcium release from sarcoplasmic reticulum


Lowers elevated temperature in malignant hyperthermia, thyroid storm, neuroleptic malignant syndrome and sepsis

Hypothermia ECG changes

Osborn J-wave

Hypothermia

Cutaneous microvasculature erythrocyte sludging

Rewarming in hypothermia

Should be at rate > 2 Celsius/ hr to reduce mortality

Complication of rapid rewarming is

Hypotension

Drug that increases risk of hypothermia

Clonidine