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21 Cards in this Set

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Formation of respiratory diverticulum Begins at....... and outgrowth from .......

4th week of IUL


ventral of foregut

Appears as an endodermal

Endoderm lining RT give rise to .... ,.....



C.T , cartilage & smooth M arised from....

— Epith + glands


splanchnic mesoderm surrounds endo

How Resp diverticulum separate from foregut.....

1) Open Esophaguses and trachea septal


2) esophago-tracheal ridges fuse to form septal


3) trachea divide to form lung buds

Failure of septum fusion results in

— Esophago-tracheal fistula


— esophageal atresia

Abnormal connection between trachea and oesophagus....

fistula

Closed esophageal end ...results of inability to swallow amniotic fluid by foetus

atresia

A B C ??

A. Atresia & fistula


B. Atresia


C. Fistula

orifice communication b/w respiratory diverticulum & foregut — seen during Development of larynx

Laryngeal orifice

Muscles & cartilages


— From which arches....


— supplied by X

—4th & 6th pharyngeal arches


—X CN nerve




superior laryngeal-4th arch


recurrent laryngeal-6t

Phases of lung development

Pseudoglandular month (1-4)


Canalicular. Mn (4-7)


Terminal sac. Mn (7- birth)


Alveolar. (Birth-8 years)


What’s the phase of


- terminal bronchioles formed ....


- resp bronchiole formed....


- Terminal sacs (primitive alveoli)....


- Mature alveoli with well-developed epith-endoth ....

Pseudoglandular


Canalicular


Terminal sac


Alveolar

Phase of SURFACTANT production ...

— Terminal sac period (27-28 wk)

+ capillaries establish close contact with sacs to establish blood- air barrier

After birth, why size of lungs increase??

due to increase in the number of respiratory bronchioles and alveoli , but not due to increase in size of alveoli

Which phase .


- no gas exchange ....


- highly vascular lung tissue...


- thin cuboidal epithelial....


- thin Type I epithelial cells....

Pseudoglandular


Canalicular


Terminal sac


Alveolar

Lungs at birth filled with fluid from ...,... and this fluid cleared at birth

- amniotic fluid, tracheal glands


aspiration of amniotic fluid caused by

Breathing movements

Fetal breathing movements


And amniotic fluid need for lung development

Surfactant deficiency results in

- infant respiratory distress syndrome


- hyaline membrane disease

In case of Surfactant deficiency


What will U give

exogenous surfactant


glucocorticoids

pleural cavities formed by

- intraembryonic coelom


- pericardio-peritoneal canals

Visceral pleura covered by... but parietal pleura covered by ....

Splanchnic mesodermal


Splanchnic mesodermal

pulmonary arteries Develop from which arch ??

6th aortic arch (pulmonary arch)