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15 Cards in this Set
- Front
- Back
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What might contribute to many birth defects of the cardiovascular system in infants?
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the complexity of septation, cardiac outflow separation, remodeling of the peripheral vasculature, and pre- to post- natal changes
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Where does the heart develop from?
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the cardiogenic mesoderm that originally lies above the cranial end of the developing neural tube
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What causes the heart region to be in its anatomically correct position?
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1. enlargement of the cranial
2. the originally paired cardiac tubes fuse (originally with "ventricular" above "atria") 3. growth of cardiac tube flexes into s-shape tube, rotating the ventricles downward and pushing atria upward |
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What is the area where cardiac progenitor cells localize within the cranial lateral plate mesoderm on both sides of the embryo?
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cardiac crescent
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What is a complex process which converts this simple tube into a four chambered heart?
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septation
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What is a key part of the septation process?
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the separation of cardiac outflow (truncus arteriosus) into a separate pulmonary and aortic arch outflow
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T/F. During embryonic development there is little remodeling that has to take place.
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False; there is extensive remodeling of the initially right and left symmetrical cardio system and a contribution from the neural crest to some vessels
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What is the first functioning organ in humans?
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heart
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What does the embryonic appear like?
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a single heart tube
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what does the embryonic single heart tube contain?
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contractile myocardium surrounding an inner endocardial (endothelial) tube
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T/F the heart is symmetric
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False, the heart is asymmetric
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When does much of the cardiac development?
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while the heart is pumping blood
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When does the heart begin beating rhythmically?
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day 22
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When does blood begin pumping?
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day 24-25
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Why does much cardiac development (remodeling and septation) need to take place?
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to provide nutrients, oxygen and waste disposal during embryonic development
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