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29 Cards in this Set

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A 7 year old boy develops a fever of 39 C while playing in his front yard a Dallas summer day. He becomes limp and lethargic, prompting his mother to rush hime to the emergency room. She stats that he never seems to sweat, and that he often feels very warm on hot days. The examining physician notes that the boy has very sparse hair and under-developed, ped-shaped teeth. A possible embryologic explanation for underdevelopment of the hair, teeth, and sweat glands would be?
A defect in gasturlation that produces undergrowth of the ectoderm.
What time of embryogenesis in days after conception is the earliest at which the defect affecting the hair, teethm and sweat glands could occur?
Week 3
The tissue of origin for the cardiac tube is:
Lateral plate mesoderm
The tissue of origin for the forebrain is:
Neural tube
The tissue of origin for the midgut is:
Endoderm
The tissue of origin for the melanocytes is:
neural crest
The tissue of origin for the spinal cord is:
neural tube
The tissue of origin for the body wall is:
Lateral plate mesoderm
The tissue of origin for tracheal epithelium is:
Endoderm
The tissue of origin for the adrenal cortex is:
Lateral plate mesoderm
Make sure to look at the images for questions 11 - 15 in chapter 4!
Make sure to look at the images for questions 11 - 15 in chapter 4!
What anchors the embryo?
connecting stalk
What provides ridigity to the embryo?
notochord
A precursor to a portion of the diaphragm is:
septum transversum
A precursor to a portion of the urinary baldder is:
allantois
What is pinched off by the lateral folds to form the gut?
Yolk sac
The tissue of origin for the skull is:
head mesoderm
The tissue of origin for fingernails is:
ectoderm
The tissue of origin for tracheal epithelium is:
endoderm
The tissue of origin for the retina is:
ectoderm
The tissue of origin for the vas deferns is:
intermediate mesoderm
The tissue of origin for the urinary bladder epithelium is:
endoderm
The tissue of origin for the ovaries is:
intermediate mesoderm
A newborn has a mass on the midline of his back, just above the sacrum. The outer layer of the mass appears translucent, with whitish-grey tissue visible beneath. The legs exhibit poor muscle tone and no withdrawal to pain. The most likely diagnosis is:

The risk of this anomaly to occur in the next pregnancy is:
Spina bifida


3 - 5%
A maternal dietry supplement that could lower the risk for neural tube defects is:
Folic Acid
A normal female has a term newborn with a fleshy tumor protuding from the anal area. A biopsy shows mutilple tissues including hair cartilage and teeth. The most likely explanation of the tumor is:
A sacrococcygeal teratoma, based on tumor location and tissues from all three germ layers.
An anomaly of the primitive streak such as a sacrococcygeal tumor would occur at which time in pregnancy?
2 - 5 days after a woman missed her period
An anomaly called Piebald trait presents with ventral, midline white patches of the skin and hair. The disorder exhibits autosomal dominant inheritance in humans and mice, and has been traced to mutation in the c-kit proto-oncogene. The assumption is that the c-kit gene product is important for melanoblast migration. The location of the white patch is thus due to:
Delayed ventral migration of neural crest cells surrounding the neural tube
The most accurate description of the infant shown in figure 4.8 is: (has a hole where the brain should be, no skull and large eyes)
Anterior neural tube defect occuring at 3 - 4 weeks post fertilzation.