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48 Cards in this Set

  • Front
  • Back
1. The most common ventricular septal defect is a:
A. persistent truncus arteriosus - always accompanied by ventricular septal defect
B. membranous septal defect
C. common ventricle
D. foramen secundum defect
B. membranous septal defect


Ventricular septal defects
Membranous ventricular septal defects
Most common ventricular septal defect
Membranous portion of ventricular septum fails to form
Muscular ventricular septal defect
Frequently multiple small openings
Caused by excessive cavitation during wall formation
Absence of interventricular septum
Common ventricle
Failure of muscular septum to form
2. The left recurrent laryngeal nerve recurs around the: arch 6
A. left primary bronchus
B. left subclavian artery
C. ductus arteriosus
D. left common carotid artery
C. ductus arteriosus
3. Which of the three primary germ layers forms the endocardial heart tube of the embryo?
A. ectoderm
B. mesoderm
C. endoderm
B. mesoderm

Early development
During week 3 angioblast cords-splanchnic mesoderm
Heart beat and blood flow first detected during week 4
Endocardial heart tubes
Initially anterior to prechordal plate; transported by embryonic folding to ventral portion of neck and then thorax
Fuse to form single tube-become endothelial lining of the heart
Primordial myocardium
Surrounds endocardial tube
Splanchnic mesoderm
Becomes myocardium
4. The hepatic sinusoids of the adult liver are derived from the:
A. posterior cardinal veins
B. supracardinal veins
C. subcardinal veins
D. vitelline veins
D. vitelline veins


Vitelline veins
Plexus around developing duodenum
Hepatic portal vein
Plexus in septum transversum invested by developing liver cords
Hepatic sinusoids and hepatic veings
Hepatic portion of inferior vena cava from right vitelline
Umbilical veins
Right vein regresses
Left vein between liver and sinus venosus regresses
Left vein persists as umbilical vein-carried all oxygenated blood from placenta to embryo
Shunt in liver-ductus venosus-shifts blood from umbilical vein to inferior vena cava bypassing liver
Cardinal veins
Anterior cardinals
Shunt shifts most blood to right anterior cardinal-becomes left brachiocephalic vein
Right anterior cardinal and common cardinal form superior vena cava
Posterior cardinals
Mostly regresses
From foot of azygos vein and common iliac veins
Replaced by supracardinals and subcardinals
Supracardinal veins
Drain body wall via intercostals veins
Subcardinal veins
Drain developing kidneys
5. Which of the following is frequently seen in premature infants?
A. patent ductus arteriosus
B. coarctation of the aorta
C. double aortic arch
D. common atrium
A. patent ductus arteriosus

Patent ductus arteriosus
May be associated with rubella infection during first trimester
May be present in premature infants
Respiratory distress syndrome can contribute
6. The coronary sinus is derived from the:
A. truncus arteriosus
B. bulbus cordis
C. primitive ventricle
D. sinus venosus
D. sinus venosus

Divisions-caudal to cranial

Sinus venosus (right atrium)
Receives blood
Fixed in place by septum transversum
Develops right and left horns
Atrium (right and left atria)
Atriventricular canal (AV valves)
Ventricle (left ventricle)
Bulbus cordis
Proximal: trabeculated portion of right ventricle
Distal: conus cordis; outflow tracts of both ventricles
Truncus arteriosus (roots of pulmonary trunk and aorta)
Distributes blood
Continuous cranially with aortic sac
Fixed in place by pharyngeal arches
7. The proximal part of the aorta is derived from the:
A. truncus arteriosus
B. bulbus cordis
C. primitive ventricle
D. sinus venosus
A. truncus arteriosus
8. The trabeculated part of the right ventricle is derived from the:
A. truncus arteriosus
B. bulbus cordis
C. primitive ventricle
D. sinus venosus
B. bulbus cordis
9. The conus cordis is derived from the:
A. truncus arteriosus
B. bulbus cordis
C. primitive ventricle
D. sinus venosus
B. bulbus cordis
10. A muscular ventricular septal defect is a defect in the _____ septum.
A. aorticopulmonary
B. atrial
C. atrioventricular
D. interventricular
D. interventricular
11. The proximal part of the internal carotid artery is derived from aortic arch:
A. 1
B. 2
C. 3
D. 4
C. 3
12. A portion of the arch of the aorta is derived from aortic arch:
A. 1
B. 2
C. 3
D. 4
D. 4
13. The renal veins are derived from which of the following?
A. vitelline veins
B. umbilical veins
C. subcardinal veins
D. posterior cardinal veins
C. subcardinal veins
14. The right atrium of the adult heart is derived from the:
A. sinus venosus
B. primitive atrium
C. both
D. neither
C. both
15. In the primitive heart tube, the sinus venosus is _____ to the truncus arteriosus.
A. cranial
B. caudal
B. caudal
16. In the primitive heart tube, the bulbus cordis is continuous cranially with the ____ and caudally with the _____.
A. atrium, ventricle
B. ventricle, sinus venosus
C. truncus arteriosus, sinus venosus
D. truncus arteriosus, ventricle
D. truncus arteriosus, ventricle
17. Which of the following persist throughout fetal development?
A. foramen primum
B. foramen secundum
C. both
D. neither
B. foramen secundum

Atrium
Portioning by 2 septa
Septum primum-from roof of common atrium
Foramen primum (ostium primum)-(obliterated)
Foramen secundum (ostium secundum)
Septum secundum –to right of septum primum
Foramen ovale
18. Which of the following is an opening in septum secundum?
A. foramen primum
B. foramen secundum
C. foramen ovale
D. interventricular foramen
C. foramen ovale
19. During the partitioning of the heart into right and left, the endocardial cushions fuse with:
A. septum primum
B. bulbar ridges
C. both
D. neither
C. both
20. The primordial interventricular septum becomes the muscular portion of the adult interventricular septum.
A. true B. false
A. true

Ventricle
Primordial interventricular septum
Muscular ridge
Midline near apex
Beomces muscular part of IV septum
21. Septum secundum forms within the developing:
A. left atrium
B. right atrium
C. left ventricle
D. right ventricle
B. right atrium
22. Which of the following divides the atrioventricular canal into left and right passages?
A. septum primum
B. septum secundum
C. truncal ridges (and bulbar) - continuous with one another; derived from neural crest
D. endocardial cushions
D. endocardial cushions


Portioning of atrioventricular canal
Endocardial cushions-form dorsal and ventral walls
Divide AV canal into left and right canals
23. Ostium secundum defects are due to faulty development of:
A. truncal ridges
B. bulbar ridges
C. endocardial cushions
D. septum primum
D. septum primum
24. Interventricular septal defects are seen in which of the following conditions?
A. persistent truncus arteriosus
B. unequal division of the truncus arteriosus
C. both
D. neither
C. both

(see ventricular septal defects in #1)

Persistent truncus arteriosus
Failure of truncal ridges and aorticopulmonary septum transversum
Common vessel drains heart and supplies systemic, pulmonary, and coronary circulation
Always accompanied by ventricular septal defect

Transportation of the great vessels
Most common cause of cyanotic heart disease
Most common arrangement
Aorta anterior and to right of pulmonary trunk
Aorta arises from right ventricle
Pulmonary trunk arises from left ventricle
Accompanied by atrial septal defect and occasionally persistent ductus arteriosus
May be due to failure of aortiocopulmonary septum to spiral during development

Unequal division of truncus arteriosus
Faulty partioning
Includes IV septal defect
May include stenosis of valves
Pulmonary valve stenosis or infundibular stenosis results in hypertrophy of the right ventricle

Teratology of Fallot
Most common abnormality involving conotruncal region
Four defects due to unequal division
Pulmonary stenosis
Ventricular septal defect
Overriding aorta
Right ventricular hypertrophy
25. Which of the following occurs if the aorticopulmonary septum fails to spiral?
A. persistent truncus arteriosus
B. unequal division of the truncus arteriosus
C. transposition of the great vessels
D. Tetralogy of Fallot
C. transposition of the great vessels
26. Constriction of the aorta proximal to the entry of the ductus arteriosus results in the condition known as postductal coarctation of the aorta.
A. true B. false
B. false
27. The left subclavian artery is derived from the:
A. left 7th intersegmental artery
B. left aortic arch 4
C. both
D. neither
A. left 7th intersegmental artery
28. The brachiocephalic trunk is derived from the left horn of the aortic sac.
A. true B. false
B. false
29. The ductus arteriosus is derived from the ___ 6th aortic arch.
A. left
B. right
A. left
30. The maxillary artery is derived from aortic arch:
A. 1
B. 2
C. 3
D. 4
A. 1
31. The hepatic portal vein develops from the:
A. umbilical veins
B. vitelline veins
C. subcardinal veins
D. posterior cardinal veins
B. vitelline veins
32. The left brachiocephalic vein connects the ______ vein with the _______ vein.
A. left anterior cardinal, left common cardinal
B. left anterior cardinal, right anterior cardinal
C. left common cardinal, left posterior cardinal
D. left posterior cardinal, right posterior cardinal
B. left anterior cardinal, right anterior cardinal
33. The superior vena cava is derived from the _____ common cardinal vein.
A. left
B. right
C. both
D. neither
B. right
34. The ___ umbilical vein normally regresses early in development, leaving only one umbilical vein to deliver blood from the placenta to the fetus.
A. left
B. right
B. right
35. Which of the following contribute to the formation of the inferior vena cava?
A. subcardinal veins
B. supracardinal veins
C. sacrocardinal veins
D. all of the above
D. all of the above

Inferior vena cava-4 segments
Hepatic segment-from hepatic vein (right vitelline)
Prerenal segment-right subcardinal
Renal segment-subcardinal and supracardinal anastomoses
Postrenal-from right supracardinal veins
36. Which of the following allow blood to bypass the lungs during fetal life?
A. ductus arteriosus
B. ductus venosus
C. both
D. neither
A. ductus arteriosus

Liver bypass
Ductus venosus-connects umbilical vein with inferior vena cava
Physiological sphincter regulates flow
Lung bypass
Blood from inferior vena cava directed through foramen ovale into left atrium
Crista dividens
Provides highly oxygenated blood for distribution to head, neck, heart, and upper extremities
Blood from right ventricle to pulmonary trunk
Part of lungs (10%)
Most through ductus arteriosus to descending aorta
37. Which of the following develops from the ductus venosus?
A. medial umbilical ligament
B. ligamentum teres hepatis
C. median umbilical ligament
D. ligamentum venosum
D. ligamentum venosum

Umbilical vein-ligamentum teres hepatic; from umbilicus to portal vein in liver
Ductus venosus-ligamentum venosum; within liver between portal vein and inferior vena cava
Umbilical arteries-medial umbilical ligament and superior vesical arteries (bladder)
Foramen ovale-fossa ovalis
Functional closure at birth
Anatomic closure by 3 months
Ductus arteriosus-ligamentum arteriosum by 12 weeks
38. The foramen ovale functionally closes at birth primarily because of bradykinin.
A. true B. false
B. false

Closure of foramen ovale
By increased pressure in left atrium and decreased pressure in right atrium
Holds valve closed
39. The foramen ovale allows blood to bypass the ____ circulation.
A. systemic
B. pulmonary
C. neither
B. pulmonary
40. At the time of birth the foramen ovale closes functionally ____ the ductus arteriosus.
A. earlier than
B. later than
C. at the same time as
A. earlier than


Foramen ovale-fossa ovalis
Functional closure at birth
Anatomic closure by 3 months

Ductus arteriosus
Pulmonary resistance lower than systemic resistance
Flow through ductus arteriosus ceases
Functionally closed within 2-3 days; anatomic closure by 4 months
41. The trachea is lined with pseudostratified ciliated columnar epithelium derived from:
A. ectoderm
B. endoderm
C. somatic mesoderm
D. splanchnic mesoderm
B. endoderm
42. The smooth muscle connective tissue and cartilage of the primary bronchus are derived from:
A. ectoderm
B. endoderm
C. somatic mesoderm
D. splanchnic mesoderm
D. splanchnic mesoderm
43. Which of the following is responsible for separating the respiratory diverticulum from the primitive foregut?
A. laryngotracheal groove
B. posterior esophageal folds
C. tracheoesophageal septum
D. bronchopulmonary segment
C. tracheoesophageal septum
44. Children born with respiratory distress syndrome frequently have immature type II cells in the alveoli.
A. true B. false
A. true

Respiratory distress syndrome (RDS); hyaline membrane disease
Associated with prematurity
Insufficient surfactant causes alveoli to collapse
45. At which of the following developmental stages is the fetus absolutely not viable?
A. terminal sac
B. alveolar
C. canalicular
D. pseudoglandular
D. pseudoglandular

Developmental stages
Pseduoglandular-5-17 weeks; terminal bronchioles only; no respiration possible
Canalicular-16-25 weeks; respiratory bronchioles and alveolar ducts
Terminal sac-24 weeks-birth; primitive alveoli with type I and II cells
Alveolar-late fetal-8 years; mature alveoli; additional respiratory structures (bronchioles, ducts, sacs, and alveoli)
46. Kupffer cells of the adult liver are derived from:
A. ectoderm
B. endoderm
C. somatic mesoderm
D. splanchnic mesoderm
D. splanchnic mesoderm
47. Which of the following arteries supplies derivatives of the foregut?
A. left umbilical artery
B. superior mesenteric artery
C. celiac trunk
D. intercostal arteries
C. celiac trunk
MATCH THE FOLLOWING WITH ITS EMBRYONIC ORIGIN.

48. stomach
49. duodenum
50. transverse colon

A. foregut
B. midgut

C. hindgut
D. foregut and midgut

E. midgut and hindgut
48. stomach A. foregut

49. duodenum D. foregut and midgut


50. transverse colon E. midgut and hindgut