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10 Cards in this Set
- Front
- Back
Randomized Clinical Trial advantages
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strongest cause/effect evidence
control for measured/unmeasured variables sometimes faster/cheaper than observational studies |
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Randomized Clinical Trial disadvantages
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costly time and moneywise
unsuitable (ethical barriers, rare outcomes) standardized interventions may be different from common practice restricts scope/narrows question |
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Cohort Trial advantages
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est sequence of events
multiple predictors and outcomes measured number of outcomes grows over time yields incidence, relative/excess risk info prospective - control over subjects and measurements retrospective - cheaper, shorter duration |
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Cohort Trail disadvantages
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large samples often required
not suitable for rare outcomes prospective - more expensive/longer duration retrospective - less control over subjects/measurements |
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Cross sectional trial advantages
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Short duration
Allows study of several outcomes good first step for a cohort study Prevalence info |
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Cross-sectional trial disadvantages
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No sequence of events
not suitable for rare predictors/outcomes No incidence or risk info |
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Case-control trial advantages
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Useful for RARE conditions
Short duration relatively inexpensive small samples yields odds ratios |
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Case-control trial disadvantages
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bias! (recall, b/c 2 populations sampled, etc)
limited to one variable outcome no sequence of events no prevalence, incidence, or excess risk info |
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Case reports advantages
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easy to accomplish
least expensive short duration often basis for future research |
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Case report disadvantages
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Prone to bias
No sequence of events Potential bias in measuring predictors |