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10 Cards in this Set

  • Front
  • Back
Randomized Clinical Trial advantages
strongest cause/effect evidence
control for measured/unmeasured variables
sometimes faster/cheaper than observational studies
Randomized Clinical Trial disadvantages
costly time and moneywise
unsuitable (ethical barriers, rare outcomes)
standardized interventions may be different from common practice
restricts scope/narrows question
Cohort Trial advantages
est sequence of events
multiple predictors and outcomes measured
number of outcomes grows over time
yields incidence, relative/excess risk info
prospective - control over subjects and measurements
retrospective - cheaper, shorter duration
Cohort Trail disadvantages
large samples often required
not suitable for rare outcomes
prospective - more expensive/longer duration
retrospective - less control over subjects/measurements
Cross sectional trial advantages
Short duration
Allows study of several outcomes
good first step for a cohort study
Prevalence info
Cross-sectional trial disadvantages
No sequence of events
not suitable for rare predictors/outcomes
No incidence or risk info
Case-control trial advantages
Useful for RARE conditions
Short duration
relatively inexpensive
small samples
yields odds ratios
Case-control trial disadvantages
bias! (recall, b/c 2 populations sampled, etc)
limited to one variable outcome
no sequence of events
no prevalence, incidence, or excess risk info
Case reports advantages
easy to accomplish
least expensive
short duration
often basis for future research
Case report disadvantages
Prone to bias
No sequence of events
Potential bias in measuring predictors