Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
14 Cards in this Set
- Front
- Back
|
DSIF function
|
Inhibits elongation
|
|
|
CTD truncation of RNA polymerase results in what activity?
|
No progression of RNA pol
|
|
|
Elongator is what type of transcription factor?
|
Histone acetyl transferase
|
|
|
NELF function
|
Inhibits elongations by binding RNA
|
|
|
P-TEFb function and what is required for it to be active?
|
Function: to antagonize NELF and DSIF.
Cdk9 is required for its kinase activity |
|
|
SII function
|
prevents arrest and promotes nascent transcript cleavage
|
|
|
TFIIF
|
suppresses pausing
|
|
|
N protein function (2 forms)
|
Non-processive: binds to box A and allows RNA processivity
Processive: associates with RNA and allows it to be processive throughout elongation and is site independent. |
|
|
lambda Q function (2 models)
|
Site release and complexes with RNA polymerase
DNA folding |
|
|
What factor is important for initiation?
Termination? |
Initiation: sigma factor determines which start codon is required
Termination is caused by a NusA factor. |
|
|
Cdk9 activity is required for two things:
|
Activation of PTEFb
Tat dependent elongation |
|
|
Rb
|
Represses RNA pol III transcription by binding to the TFIIIB portion
|
|
|
Ck2
|
Phosphorylates TFIIIB subunit and stimulates the assembly of the complex
|
|
|
ERK
|
phosphorylates BRF1
stiumlates the assembly of the complex. |
