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5 Cards in this Set

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Ethics committees will
Ethics committees will discuss the following:
1. What is the study trying to achieve?
2. Does the methodology align with aim?
3. Are the objectives for the trial relevant – is there need for this study?
4. What are the possible merits for participants?
5. Are there flaws in the methodology?
6. What are the end points of this study? When are results marked significant?
7. Are there any forms of payment or coercion used? Are they appropriate?
8. How are the results being handled?
9. Is consent attained?
10. Have the participants been/will be informed of objectives, risks, outcomes etc…
Key Developmental Milestones of 2yo
Basic motor skills, such as:
- Walking up stairs, one step at a time with two feet on each step
- Able to jump with two feet together
- Run in a straight line
-Throw a ball
Fine motor skills, such as:
- Scribble circles on paper
Basic language skills:
- Can string words together to create basic sentences to communicate needs, although he may not be easily understandable to strangers
Social skills:
Plays alongside other children, though not necessarily engaging with them
Suspicious that a child may be the victim of child abuse. What signs in
a) in the child, b) the parent (if suspected) could signal child abuse?

If you were almost certain that James was a victim of abuse, what would be your course of action?
a)Lack of stranger anxiety, Toddler may indiscriminately seek affection (social promiscuity), Apathetic and withdrawn behaviour, very watchful and alert, physical injuries

b)appears to be indifferent towards the child, offers conflicting or unconvincing explanation for child's injuries, denies presence of- or blames child for- problems at (pre)school or home

c)
-Involvement of Child Youth and Family.
-Don’t allow child to go home with carers if you think there is serious and imminent danger.
-Don’t need to involve police yourself as CYFs will deal with that aspect
Many genetic studies have been done investigating possible genetic causality and heretibality for T1D and T2D.

Comment on the genetics of the two diseases, noting if one has a stronger genetic component and/or pattern of heritability.
Both Type I and Type II diabetes have a genetic component, but it is larger in Type I.
The inheritance of Type II diabetes is complex, and involves many genes. Concordance is high in monozygotic twins suggesting a high level of heritability, however it is also high in dizygotic twins, which suggests a large contribution from environment.
Type I diabetes involves genes in the HLA region, which is a major locus for control of the immune system. Heritability is very high, especially in monozygotic twins.
Differences between confidentiality & privacy
Confidentiality = Doctor-patient relationship, includes everything discussed between the two people, information which may or may not be considered private information. We aren't allowed to disclose anything that can be traced back to patients (even implicitly) and if we do they can charge us for it, regardless of whether harm occurred.

Privacy
=refers to our right to control what information of ours is disseminated (implying that the info was taken, not given willingly), and applies to everyone. So anyone can sue another person for breach of privacy, but they have to prove harm was done.

Summary:
i.e. Confidentiality protects Communication, Privacy protects the Person (autonomy, control of own information, etc)