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39 Cards in this Set

  • Front
  • Back
What is produced from the oxidation of fuels oxidized by oxygen w/ production of water and ATP?
NADH and FADH2
What are NADH and FAD doing in Os Phos?
Electron carriers
The energy released from the passage of protons back across the inner mitochondrial membranes down the gradient used to make what?
ATP
What is the name of process to make ATP?
Chemiosmotic Theory
what causes the protons to leave the interior of the mitochondria?
the elctron flow
Oxidation is?
transferring of electrons
Redox is?
making ATP
What is embedded in the mitochondria matrix that helps that passes electrons to Complex III for pumping?
CoEnzyme Q
Cytochrome C is which complex?
Complex IV
Another name for Coenzyme Q?
Ubiquinone
Hyper Complex I has what effect on ATP release?
Decreases
FAD transfers electrons to FeS centers which pass them on to?
(Complex II:Succinate Dehydrogenase)
CoQ
Are protons pumped when electrons are transferred to CoQ?
(Complex II:Succinate Dehydrogenase)
No
The lack of protons pumped in the electron transfer to CoQ results in and increase or decrease of ATP?
Decrease
(ATP Synthase)
The F1 portion of the ATP synthase consists of what and how many dimers?
3 alpha/beta-dimers
(ATP Synthase)
Do the operators (alpha/beta dimers) work in sync or independent?
Independent
(ATP Synthase)
(ATP Synthase)
Influx of what causes the interaction of the Gamma subunit with the alpha/beta dimers to change?
Proton influx
(ATP Synthase)
(ATP Synthase)
The energy poduced from the proton flow causes a conformational change creating what?
ATP
(ATP Synthase)
What needs to happen to allow the release of ATP locked in the Beta portion of the dimer?
Catalysis of the Gamma subunit
Brown Adipose Tissue is found where on infants?
Neck, back and kidneys
What is contained within Brown Adipose Tissue that produces heat?
Uncoupling protein called THERMOGENIN that uncouples mitochondria
What activates Thermogenin?
Norepinephrine release from cold chills or food intake
What is a Symport and an example of one?
Translocase which moves 2 ions in same direction across the membrane.
ie as Proton moves with a Pyruvate into the mitochondrial matrix there is no net change in charge
What is a Antiport and an example of one?
a charged molecule is exchanged for a different charged molecule
ie ATP-ADP Translocase where ATP in the mitochondrial matrix is exchanged for ADP
What is a Uniport and an example of one?
Only one molecule is transported
ie a Calcium channel which can allow Calcium to enter the mitochondria
Transport across the inner mitochondrial membrane is executed by?
Translocase
What binds Hexokinase in the outer mitochondrial membrane?
Voltage Dependent Anion Channels
Is hexokinase a cytosolic protein?
Yes
The binding of hexokinase to Voltage Dependent Anion Channels on the outer membrane of the mitochondrial membrane permits what to happen?
Hexokinase now has access to newly exported ATP
Creatine Phosphate plays what role in energy buffering in the brain, skeletal muscles and heart?
Contains high energy phosphate bonds. A net transfer of high energy phosphate from it to ADP to form ATP. As the ATP levels return to resting levels, creatine phosphate is regenerated.
What form of energy is stored in the cardiac muscle?
Creatine Phosphate
Creatine Phosphate is used to generate more and where?
ATP in the heart
As heart rate increases, what happens to ATP?
It is depleted
In aerobic conditions, within few seconds of exercise, when ATP depletes, what takes over its production?
Creatine Phosphate
Creatine Phosphate plays what role in energy buffering in the brain, skeletal muscles and heart?
Contains high energy phosphate bonds. A net transfer of high energy phosphate from it to ADP to form ATP. As the ATP levels return to resting levels, creatine phosphate is regenerated.
What form of energy is stored in the cardiac muscle?
Creatine Phosphate
Creatine Phosphate is used to generate more and where?
ATP in the heart
As heart rate increases, what happens to ATP?
It is depleted
In aerobic conditions, within few seconds of exercise, when ATP depletes, what takes over its production?
Creatine Phosphate