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39 Cards in this Set
- Front
- Back
What is produced from the oxidation of fuels oxidized by oxygen w/ production of water and ATP?
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NADH and FADH2
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What are NADH and FAD doing in Os Phos?
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Electron carriers
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The energy released from the passage of protons back across the inner mitochondrial membranes down the gradient used to make what?
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ATP
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What is the name of process to make ATP?
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Chemiosmotic Theory
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what causes the protons to leave the interior of the mitochondria?
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the elctron flow
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Oxidation is?
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transferring of electrons
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Redox is?
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making ATP
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What is embedded in the mitochondria matrix that helps that passes electrons to Complex III for pumping?
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CoEnzyme Q
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Cytochrome C is which complex?
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Complex IV
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Another name for Coenzyme Q?
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Ubiquinone
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Hyper Complex I has what effect on ATP release?
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Decreases
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FAD transfers electrons to FeS centers which pass them on to?
(Complex II:Succinate Dehydrogenase) |
CoQ
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Are protons pumped when electrons are transferred to CoQ?
(Complex II:Succinate Dehydrogenase) |
No
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The lack of protons pumped in the electron transfer to CoQ results in and increase or decrease of ATP?
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Decrease
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(ATP Synthase)
The F1 portion of the ATP synthase consists of what and how many dimers? |
3 alpha/beta-dimers
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(ATP Synthase)
Do the operators (alpha/beta dimers) work in sync or independent? |
Independent
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(ATP Synthase)
(ATP Synthase) Influx of what causes the interaction of the Gamma subunit with the alpha/beta dimers to change? |
Proton influx
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(ATP Synthase)
(ATP Synthase) The energy poduced from the proton flow causes a conformational change creating what? |
ATP
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(ATP Synthase)
What needs to happen to allow the release of ATP locked in the Beta portion of the dimer? |
Catalysis of the Gamma subunit
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Brown Adipose Tissue is found where on infants?
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Neck, back and kidneys
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What is contained within Brown Adipose Tissue that produces heat?
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Uncoupling protein called THERMOGENIN that uncouples mitochondria
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What activates Thermogenin?
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Norepinephrine release from cold chills or food intake
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What is a Symport and an example of one?
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Translocase which moves 2 ions in same direction across the membrane.
ie as Proton moves with a Pyruvate into the mitochondrial matrix there is no net change in charge |
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What is a Antiport and an example of one?
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a charged molecule is exchanged for a different charged molecule
ie ATP-ADP Translocase where ATP in the mitochondrial matrix is exchanged for ADP |
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What is a Uniport and an example of one?
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Only one molecule is transported
ie a Calcium channel which can allow Calcium to enter the mitochondria |
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Transport across the inner mitochondrial membrane is executed by?
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Translocase
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What binds Hexokinase in the outer mitochondrial membrane?
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Voltage Dependent Anion Channels
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Is hexokinase a cytosolic protein?
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Yes
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The binding of hexokinase to Voltage Dependent Anion Channels on the outer membrane of the mitochondrial membrane permits what to happen?
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Hexokinase now has access to newly exported ATP
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Creatine Phosphate plays what role in energy buffering in the brain, skeletal muscles and heart?
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Contains high energy phosphate bonds. A net transfer of high energy phosphate from it to ADP to form ATP. As the ATP levels return to resting levels, creatine phosphate is regenerated.
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What form of energy is stored in the cardiac muscle?
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Creatine Phosphate
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Creatine Phosphate is used to generate more and where?
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ATP in the heart
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As heart rate increases, what happens to ATP?
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It is depleted
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In aerobic conditions, within few seconds of exercise, when ATP depletes, what takes over its production?
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Creatine Phosphate
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Creatine Phosphate plays what role in energy buffering in the brain, skeletal muscles and heart?
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Contains high energy phosphate bonds. A net transfer of high energy phosphate from it to ADP to form ATP. As the ATP levels return to resting levels, creatine phosphate is regenerated.
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What form of energy is stored in the cardiac muscle?
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Creatine Phosphate
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Creatine Phosphate is used to generate more and where?
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ATP in the heart
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As heart rate increases, what happens to ATP?
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It is depleted
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In aerobic conditions, within few seconds of exercise, when ATP depletes, what takes over its production?
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Creatine Phosphate
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