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50 Cards in this Set

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Normal range: Sodium
135 - 145 mEq/L
Normal range: Potassium
3.5 - 5.2 mEq/L
Normal range: Magnesium
1.6 - 2.6 mg/dL
Normal range: Calcium
8.2 - 10.6 mg/dL
Normal range: Phosphorus
2.5 - 4.5 mg/dL
What is the role of sodium?

- responsible for stimulation of neuromuscular activity and acid-base balance


- regulates renal retention and excretion of water


- maintains osmotic pressure of extracellular fluid

Hyponatremia

- loss of sodium or water gain that dilutes extracellular fluid


- (Critical Red Flag: < 120)


- affects functioning of voluntary and involuntary muscles

Causes of hyponatremia

- nausea, vomiting, and diarrhea


- excess diuretic dosage


- liver failure


- congestive heart failure (heart doesn't pump as well as it should)


- increased hypotonic IV fluids

Symptoms of hyponatremia

- anorexia, nausea, cramps


- fatigue, lethargy, muscle weakness


- headache, confusion, seizures


- decreased BP

Treatment of hyponatremia

- intake foods high in sodium


- IV Ringer's Lactate or 0.9% NS

Hypernatremia

- above 145 mEq/L


- (Critical Red Flag: >160)

Causes of hypernatremia

- dehydration-fluid loss through nausea, vomiting, and diarrhea


- diabetes ketoacidosis


- fever

Symptoms of hypernatremia

- excessive thirst


- dry and sticky tongue/mucosa


- weakness, lethargy, agitation


- edema


- elevated BP

Treatment of hypernatremia

- increase water intake


- 5% dextrose in water (hypotonic solution)


- diuretics

What is the role of potassium?

- electrical impulses in cardiac and skeletal muscle


- most abundant intracellular cation


- helps maintain acid-base balance and has inverse relationship to metabolic pH

Hypokalemia

- below 3.5 mEq/L


- (Critical Red Flag: < 2.5)

Causes of hypokalemia



- ETOH (alcohol) abuse


- Congestive Heart Failure


- hypertension


- vomiting and diarrhea


- respiratory alkalosis


- inadequate dietary intake of K+ (rare, but often accompany other causes of K+ depletion)

Treatment of hypokalemia

- foods rich in K+


- balanced electrolyte solutions


- sports drinks


- IV K+ (administered cautiously to prevent hyperkalemia)

Hyperkalemia

- above 5.0 mEq/L


- (Critical Red Flag: >6)

Causes of hyperkalemia

- metabolic acidosis


- dehydration


- renal failure


- tissue damage - burns

Symptoms of hyperkalemia

- dysrhythmias


- ECG changes


- muscles weakness or paralysis


- bradycardia


- tingling and numbness


- nausea, vomiting, and diarrhea

Treatment of hyperkalemia

- insulin (moves K+ into the cell)


- D50 (prevents hypoglycemia caused by the infusion of insulin)


- IV Calcium Gluconate also given at the same time to counteract cardiac effects of potassium


- Sodium Bicarbonate (treats the acidosis caused when K+ moves into cell and pushes hydrogen ions into the serum)


- hemodialysis or peritoneal dialysis


- decreased dietary K+ intake

What is the role of calcium?

plays a role in:


- coagulation


- neuromuscular conduction


- intracellular regulation


- control of skeletal and cardiac muscle contractility

Hypocalcemia

- below 8.2 mg/dL


- (Critical Red Flag: < 7)

Causes of hypocalcemia

- multiple blood transfusions


- pancreatitis


- removal of parathyroid glands


- alcohol abuse


- inadequate intake of Vitamin D


- loop diuretics

Symptoms of hypocalcemia

- neuromuscular excitability or tetany (severe muscle spasms)


- dysrhythmias


- hypotension


- Chvostek's sign: elicited by tapping on the facial nerve just above the temple. Positive sign is a twitch of the nose or lip


- Trousseau sign: contraction of hand or fingers when the arterial blood flow is cut off for 5 mins

Treatment of hypocalcemia

- increased dietary intake


- administration of medications

Hypercalcemia

- above 10.6 mg/dL


- (Critical Red Flag: >12)

Causes of hypercalcemia

- prolonged immobilization


- dehydration


- cancer


- hyperparathyroidism and excess hormone secretion (increased resorption of calcium from bones)

Symptoms of hypercalcemia

- sedative effect on neuromuscular transmission


- kidney stones occur from excess calcium in urine


- altered behavior or confusion


- critically high levels cause heart block and cardiac arrest

Treatment of hypercalcemia

- eliminate calcium through kidneys through IV fluids (usually 0.9% NS)


- loop diuretic


- calcitonin

What is the role of magnesium?

required for transmission of nerve impulses and muscle relaxation

Hypomagnesemia

- below 1.6 mg/dL


- (Critical Red Flag: < 1.2)

Causes of hypomagnesemia

- malnutrition


- chronic alcoholism


- renal disease


- pancreatitis


- metabolic acidosis

Symptoms of hypomagnesemia
increased neuromuscular excitability and tetany (severe muscle spasms)
Treatment of hypomagnesemia

- treat underlying cause


- medications including magnesium supplements, such as antacids

Causes of hypermagnesemia

- rare, but often caused by renal failure


- magnesium-containing antacids (e.g., Gaviscon, Gelusil)

Symptoms of hypermagnesemia

- nausea and vomiting


- muscle weakness


- hypotension


- bradycardia


- respiratory depression

Treatment of hypermagnesemia

- removal of magnesium by dialysis


- avoidance of magnesium-containing substances

Hypermagnesemia

- above 2.6 mg/dL


- (Critical Red Flag: >6.1)

Hypophosphatemia
- less than 2.5 mg/dL
What is the role of phosphorus?

- important for energy (ATP) production


- metabolism


- red blood cell function

Causes of hypophosphatemia

- alcohol abuse


- malabsorption syndromes (decreased absorption from GI)


- increased excretion by the kidneys


- respiratory alkalosis (because of cellular use of phosphate for accelerated glycolysis (ATP) formation)

Symptoms of hypophosphatemia

- conditions related to reduced capacity for oxygen transport by red blood cells and disturbed energy metabolism


- when severe: confusion, coma, convulsions, and respiratory failure (due to muscle weakness)

Treatment of hypophosphatemia

- treat underlying condition


- oral phosphorus supplements or IV

Hyperphosphatemia
- above 4.5 mg/dL
Causes of hyperphosphatemia

- acute or chronic renal failure


- phosphate is released into extracellular fluid when cells are damaged or destroyed (e.g., chemotherapy)


- long-term laxative abuse

Symptoms of hyperphosphatemia
- symptoms primarily related to low serum calcium levels (caused by high phosphate levels) similar to symptoms of hypocalcemia
Treatment of hyperphosphatemia

- dialysis


- avoid high phosphorus diet


- IV 0.9% NS, aluminum hydroxide, or glucose and insulin to drive phosphate into cells