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31 Cards in this Set
- Front
- Back
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Most important antibody for complement activation
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IgM > IgG
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Primary antibody for defense against helminths
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IgE
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Antibody that provides mucosal immunity
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IgA
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Antibody that crosses the placenta to protect neonates
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IgG
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Major opsonizing antibody
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IgG
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Neutralizing antibodies
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IgG, IgA
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Antibody that mediates mast cell degranulation
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IgE
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Binds to dimeric IgA and facilitates transcytosis
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Poly-Ig Receptor
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NK cell-mediated killing of IgG-coated cells
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Antibody-dependent cellular cytotoxicity
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Fc receptor involved in ADCC
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Fc gamma RIII (CD16)
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Fc receptor involved mast cell degranulation
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Fc epsilon RI
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Fc receptor involved in down-regulation of B cell activity
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Fc gamma RIIB (CD32)
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Fc receptor involved in transporting IgG from blood to extracellular spaces
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FcRn
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C3 convertase of classical pathway
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C4b2a
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Complement products that are chemotactic
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C5a > C3a, C4a,
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C3 convertase of alternative pathway
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C3bBb
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Stabilizes C3bBb complex on pathogen surface
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Properdin
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Components of membrane attack complex
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C5b6789
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C5 convertase of classical pathway
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C4b2a3b
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C5 convertase of alternative pathway
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C3bBbC3b
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Component of MAC that polymerizes
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C9
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Complement product that is an opsonin
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C3b
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Deficiency of this complement regulatory protein results in Hereditary Angioneurotic Edema
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C1 inhibitor
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Host protein that displaces Bb from C3b
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Decay accelerating factor
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Proteins unique to the alternative pathway of complement
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Properdin, Factor B and D
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Type of immune protection induced by bacterial vaccines
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Antibodies
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Type of immune protection from live attenuated viral vaccines
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Antibodies and CMI
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Type of immune protection from subunit vaccines
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Antibody
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Type of immune protection from conjugate vaccines
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Antibody
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Type of immune protection from synthetic vaccines
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Antibody
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Mechanism of immune evasion by altering surface antigens recognized by immune system
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Antigenic variation
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